CXC Chemokine Ligand 10 (CXCL10) ELISA Kit for Human

Name: Human CXCL10 ELISA Kit; CXC Chemokine Ligand 10; MyBioSource
Brand: MyBioSource
SKU: MBS748275
Price: 580 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS748275

MBS748275 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CXC chemokine ligand 10 (CXCL10) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$580 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

CXC chemokine ligand 10 (CXCL10), ELISA Kit

Full Product Name

Human CXC chemokine ligand 10 ELISA Kit

Product Gene Name

CXCL10 elisa kit

Species Reactivity

Human

Assay Type

Competitive

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

0.5-10ng/mL

Sensitivity

0.1ng/mL

Preparation and Storage

Store all reagents at 2-8 degree C.

Molecular Weight

10,881 Da

OMIM

147310

Sample Preparation

We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team

Product Categories/Family for CXCL10 elisa kit

Immunology

ISO Certification

Manufactured in an ISO 13485:2016 Certified Laboratory.

Other Notes

Small volumes of CXCL10 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CXCL10. It may not necessarily be applicable to this product.

NCBI GI #

149999382

NCBI GeneID

3627

NCBI Accession #

NP_001556.2

UniProt Secondary Accession #

Q96QJ5

UniProt Related Accession #

P02778

GenBank Nucleotide #

NM_001565.3

NCBI Official Full Name

C-X-C motif chemokine 10

NCBI Official Synonym Full Names

chemokine (C-X-C motif) ligand 10

NCBI Official Symbol

CXCL10

NCBI Official Synonym Symbols

C7; IFI10; INP10; IP-10; crg-2; mob-1; SCYB10; gIP-10

UniProt Protein Name

C-X-C motif chemokine 10

UniProt Synonym Protein Names

10 kDa interferon gamma-induced protein; Gamma-IP10; IP-10; Small-inducible cytokine B10Cleaved into the following chain:CXCL10(1-73)

Protein Family

C-X-C motif chemokine

UniProt Gene Name

CXCL10

UniProt Synonym Gene Names

INP10; SCYB10; Gamma-IP10; IP-10

UniProt Entry Name

CXL10_HUMAN

NCBI Protein Information

C-X-C motif chemokine 10; gamma IP10; gamma-IP10; small-inducible cytokine B10; interferon-inducible cytokine IP-10; 10 kDa interferon gamma-induced protein; protein 10 from interferon (gamma)-induced cell line; small inducible cytokine subfamily B (Cys-X-Cys), member 10

NCBI Summary for CXCL10

This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq, Sep 2014]

UniProt Comments for CXCL10

CXCL10: Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Secreted, signal peptide; Chemokine; Motility/polarity/chemotaxis; Secreted

Chromosomal Location of Human Ortholog: 4q21

Cellular Component: extracellular space; extracellular region; external side of plasma membrane

Molecular Function: heparin binding; protein binding; CXCR3 chemokine receptor binding; chemokine activity; cAMP-dependent protein kinase regulator activity; receptor binding

Biological Process: muscle development; blood circulation; protein secretion; positive regulation of leukocyte chemotaxis; positive regulation of cAMP metabolic process; chemotaxis; signal transduction; regulation of cell proliferation; G-protein coupled receptor protein signaling pathway; negative regulation of angiogenesis; cell surface receptor linked signal transduction; response to vitamin D; cell-cell signaling; positive regulation of cell proliferation; response to gamma radiation; immune response; positive regulation of transcription from RNA polymerase II promoter; response to cold; positive regulation of release of sequestered calcium ion into cytosol; negative regulation of myoblast differentiation; inflammatory response; regulation of protein kinase activity; defense response to virus

Research Articles on CXCL10

1. Increased CXCL9 serum levels in hepatitis C-related mixed cryoglobulinemia, with autoimmune thyroiditis, associated with high levels of CXCL10.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CXCL10 elisa kit

Reference Product	PubMed Publications
CXCL9 elisa kit	>876 publications with CXCL10 and CXCL9
CXCR3 elisa kit	>795 publications with CXCL10 and CXCR3
CCL5 elisa kit	>618 publications with CXCL10 and CCL5
CXCL11 elisa kit	>444 publications with CXCL10 and CXCL11
CCR5 elisa kit	>167 publications with CXCL10 and CCR5
CCL20 elisa kit	>103 publications with CXCL10 and CCL20
CCL11 elisa kit	>97 publications with CXCL10 and CCL11
CXCR2 elisa kit	>48 publications with CXCL10 and CXCR2
CCR3 elisa kit	>47 publications with CXCL10 and CCR3
CCR1 elisa kit	>46 publications with CXCL10 and CCR1

Pathways associated with CXCL10 elisa kit

Products by Pathway	Pathway Diagram
CXCR3-mediated Signaling Events Pathway antibodies	CXCR3-mediated Signaling Events Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytosolic DNA-sensing Pathway antibodies	Cytosolic DNA-sensing Pathway Diagram
Cytosolic DNA-sensing Pathway antibodies	Cytosolic DNA-sensing Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram

Diseases associated with CXCL10 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>1092 publications with CXCL10 and Inflammation
Necrosis Antibodies	>641 publications with CXCL10 and Necrosis
Lung Diseases Antibodies	>313 publications with CXCL10 and Lung Diseases
Liver Diseases Antibodies	>210 publications with CXCL10 and Liver Diseases
Cardiovascular Diseases Antibodies	>159 publications with CXCL10 and Cardiovascular Diseases
Fibrosis Antibodies	>121 publications with CXCL10 and Fibrosis
Neoplasms, Experimental Antibodies	>110 publications with CXCL10 and Neoplasms, Experimental
Kidney Diseases Antibodies	>81 publications with CXCL10 and Kidney Diseases
Lung Injury Antibodies	>60 publications with CXCL10 and Lung Injury
Pneumonia Antibodies	>58 publications with CXCL10 and Pneumonia

Organs/Tissues associated with CXCL10 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>1925 publications with CXCL10 and Blood
Lung Antibodies	>430 publications with CXCL10 and Lung
Liver Antibodies	>255 publications with CXCL10 and Liver
Kidney Antibodies	>168 publications with CXCL10 and Kidney
Lymph Node Antibodies	>154 publications with CXCL10 and Lymph Node
Muscle Antibodies	>115 publications with CXCL10 and Muscle
Intestine Antibodies	>87 publications with CXCL10 and Intestine
Nerve Antibodies	>58 publications with CXCL10 and Nerve
Uterus Antibodies	>31 publications with CXCL10 and Uterus
Placenta Antibodies	>25 publications with CXCL10 and Placenta