Forkhead Box Protein P1 (FOXP1) ELISA Kit for Sheep

Name: Sheep FOXP1 ELISA Kit; Forkhead Box Protein P1; MyBioSource
Brand: MyBioSource
SKU: MBS750458
Price: 580 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS750458

Principle of the assay: FOXP1 ELISA kit applies the competitive enzyme immunoassay technique utilizing a monoclonal anti-FOXP1 antibody and an FOXP1-HRP conjugate. The assay sample and buffer are incubated together with FOXP1-HRP conjugate in pre-coated plate… More details

$580 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Forkhead Box Protein P1 (FOXP1), ELISA Kit

Full Product Name

Sheep Forkhead Box Protein P1 ELISA Kit

Product Gene Name

FOXP1 elisa kit

Species Reactivity

Sheep

Assay Type

Competitive

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

1.0-25ng/mL

Sensitivity

0.1ng/mL

Preparation and Storage

Store all reagents at 2-8 degree C.

Molecular Weight

75,246 Da

OMIM

gene 613670

Sample Preparation

We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team

Product Categories/Family for FOXP1 elisa kit

Signal Transduction

ISO Certification

Manufactured in an ISO 13485:2016 Certified Laboratory.

Other Notes

Small volumes of FOXP1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FOXP1 purchase

MBS750458 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Forkhead Box Protein P1 (FOXP1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FOXP1. The ELISA analytical biochemical technique of the MBS750458 kit is based on FOXP1 antibody-FOXP1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FOXP1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FOXP1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for FOXP1. It may not necessarily be applicable to this product.

NCBI GI #

348605235

NCBI GeneID

27086

NCBI Accession #

NP_001231745.1

UniProt Secondary Accession #

Q8NAN6; Q9BSG9; Q9H332; Q9H333; Q9P0R1; A3QVP8; B3KV70; G5E9V8

UniProt Related Accession #

Q9H334

GenBank Nucleotide #

NM_001244816.1

NCBI Official Full Name

forkhead box protein P1 isoform 1

NCBI Official Synonym Full Names

forkhead box P1

NCBI Official Symbol

FOXP1

NCBI Official Synonym Symbols

QRF1; 12CC4; hFKH1B; HSPC215

UniProt Protein Name

Forkhead box protein P1

Protein Family

Forkhead box protein

UniProt Gene Name

FOXP1

UniProt Synonym Gene Names

HSPC215

UniProt Entry Name

FOXP1_HUMAN

NCBI Protein Information

forkhead box protein P1; glutamine-rich factor 1; fork head-related protein like B

NCBI Summary for FOXP1

This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

UniProt Comments for FOXP1

FOXP1: Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B-cell development. Forms homodimers and heterodimers with FOXP2 and FOXP4. Dimerization is required for DNA-binding. Interacts with CTBP1. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: C2H2-type zinc finger protein; Transcription factor; Cell cycle regulation; DNA-binding

Chromosomal Location of Human Ortholog: 3p14.1

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; androgen receptor binding; sequence-specific DNA binding; metal ion binding

Biological Process: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; macrophage activation; regulation of monocyte differentiation; monocyte activation; positive regulation of smooth muscle cell proliferation; regulation of inflammatory response; regulation of interleukin-1 beta secretion; regulation of tumor necrosis factor production; response to lipopolysaccharide; osteoclast differentiation; negative regulation of transcription, DNA-dependent; negative regulation of B cell apoptosis; endothelial cell activation

Disease: Mental Retardation With Language Impairment And With Or Without Autistic Features

Research Articles on FOXP1

1. Non-immunoglobulin heavy chain rearrangements of FOXP1 are usually acquired during clinical course of various lymphoma subtypes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FOXP1 elisa kit

Reference Product	PubMed Publications
FOXP2 elisa kit	>49 publications with FOXP1 and FOXP2
BCL6 elisa kit	>31 publications with FOXP1 and BCL6
MALT1 elisa kit	>15 publications with FOXP1 and MALT1
FOXP4 elisa kit	>14 publications with FOXP1 and FOXP4
NCOR2 elisa kit	>2 publications with FOXP1 and NCOR2

Pathways associated with FOXP1 elisa kit

Products by Pathway	Pathway Diagram
MicroRNAs In Cancer Pathway antibodies	MicroRNAs In Cancer Pathway Diagram
MicroRNAs In Cancer Pathway antibodies	MicroRNAs In Cancer Pathway Diagram

Diseases associated with FOXP1 elisa kit

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>24 publications with FOXP1 and Nervous System Diseases
Breast Neoplasms Antibodies	>10 publications with FOXP1 and Breast Neoplasms
Lung Neoplasms Antibodies	>10 publications with FOXP1 and Lung Neoplasms
Child Development Disorders, Pervasive Antibodies	>9 publications with FOXP1 and Child Development Disorders, Pervasive
Cell Transformation, Neoplastic Antibodies	>8 publications with FOXP1 and Cell Transformation, Neoplastic
Inflammation Antibodies	>6 publications with FOXP1 and Inflammation
Carcinoma, Hepatocellular Antibodies	>6 publications with FOXP1 and Carcinoma, Hepatocellular
Learning Disorders Antibodies	>5 publications with FOXP1 and Learning Disorders
Liver Diseases Antibodies	>4 publications with FOXP1 and Liver Diseases
Disease Models, Animal Antibodies	>4 publications with FOXP1 and Disease Models, Animal

Organs/Tissues associated with FOXP1 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>67 publications with FOXP1 and Blood
Brain Antibodies	>46 publications with FOXP1 and Brain
Lung Antibodies	>26 publications with FOXP1 and Lung
Muscle Antibodies	>24 publications with FOXP1 and Muscle
Lymph Node Antibodies	>23 publications with FOXP1 and Lymph Node
Heart Antibodies	>16 publications with FOXP1 and Heart
Embryonic Tissue Antibodies	>15 publications with FOXP1 and Embryonic Tissue
Bone Antibodies	>13 publications with FOXP1 and Bone
Stomach Antibodies	>13 publications with FOXP1 and Stomach
Skin Antibodies	>12 publications with FOXP1 and Skin