Tryptophan-2, 3-Dioxygenase (TDO) ELISA Kit for Chicken

Name: Chicken TDO ELISA Kit; Tryptophan-2, 3-Dioxygenase; MyBioSource
Brand: MyBioSource
SKU: MBS754681
Price: 580 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS754681

MBS754681 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Tryptophan-2, 3-dioxygenase (TDO) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$580 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Tryptophan-2, 3-dioxygenase (TDO), ELISA Kit

Full Product Name

Chicken Tryptophan-2, 3-dioxygenase ELISA Kit

Product Gene Name

TDO elisa kit

Species Reactivity

Chicken

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Preparation and Storage

Store all reagents at 2-8 degree C.

Molecular Weight

47,872 Da

OMIM

191070

Sample Preparation

We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team

Product Categories/Family for TDO elisa kit

Signal Transduction

ISO Certification

Manufactured in an ISO 13485:2016 Certified Laboratory.

Other Notes

Small volumes of TDO elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TDO. It may not necessarily be applicable to this product.

NCBI GI #

5032165

NCBI GeneID

6999

NCBI Accession #

NP_005642.1

UniProt Secondary Accession #

A8K053

UniProt Related Accession #

P48775

GenBank Nucleotide #

NM_005651.3

NCBI Official Full Name

tryptophan 2,3-dioxygenase

NCBI Official Synonym Full Names

tryptophan 2,3-dioxygenase

NCBI Official Symbol

TDO2

NCBI Official Synonym Symbols

TO; TDO; TPH2; TRPO

UniProt Protein Name

Tryptophan 2,3-dioxygenase

UniProt Synonym Protein Names

Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; TO; TRPO; Tryptophan pyrrolase; Tryptophanase

Protein Family

Tryptophan 2,3-dioxygenase

UniProt Gene Name

TDO2

UniProt Synonym Gene Names

TDO; TDO; TO; TRPO

UniProt Entry Name

T23O_HUMAN

NCBI Protein Information

tryptophan 2,3-dioxygenase; tryptophanase; tryptophan oxygenase; tryptophan pyrrolase; tryptamin 2,3-dioxygenase

NCBI Summary for TDO

This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012]

UniProt Comments for TDO

TDO2: Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin. Belongs to the tryptophan 2,3-dioxygenase family.

Protein type: Oxidoreductase; EC 1.13.11.11; Amino Acid Metabolism - tryptophan

Chromosomal Location of Human Ortholog: 4q31-q32

Cellular Component: cytosol

Molecular Function: amino acid binding; metal ion binding; heme binding; oxygen binding; tryptophan 2,3-dioxygenase activity

Biological Process: tryptophan catabolic process to acetyl-CoA; tryptophan catabolic process to kynurenine; tryptophan catabolic process

Research Articles on TDO

1. Identification of 12 polymorphisms in the human TDO2 promoter region, 2 of them corresponding to previously unknown single-nucleotide polymorphisms and 3 of them located in putative glucocorticoid-responsive elements.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TDO elisa kit

Reference Product	PubMed Publications
IDO1 elisa kit	>6 publications with TDO and IDO1

Pathways associated with TDO elisa kit

Products by Pathway	Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Amino Acids And Derivatives Pathway antibodies	Metabolism Of Amino Acids And Derivatives Pathway Diagram
Monoamine Transport Pathway antibodies	Monoamine Transport Pathway Diagram
NAD Biosynthesis II (from Tryptophan) Pathway antibodies	NAD Biosynthesis II (from Tryptophan) Pathway Diagram
NAD Biosynthesis II (from Tryptophan) Pathway antibodies	NAD Biosynthesis II (from Tryptophan) Pathway Diagram
Tryptophan Catabolism Pathway antibodies	Tryptophan Catabolism Pathway Diagram
Tryptophan Metabolism Pathway antibodies	Tryptophan Metabolism Pathway Diagram
Tryptophan Metabolism Pathway antibodies	Tryptophan Metabolism Pathway Diagram
Tryptophan Metabolism Pathway antibodies	Tryptophan Metabolism Pathway Diagram

Diseases associated with TDO elisa kit

Disease Name	Pubmed Publications
Brain Diseases Antibodies	>9 publications with TDO and Brain Diseases
Nervous System Diseases Antibodies	>8 publications with TDO and Nervous System Diseases
Disease Models, Animal Antibodies	>3 publications with TDO and Disease Models, Animal
Learning Disorders Antibodies	>3 publications with TDO and Learning Disorders
Memory Disorders Antibodies	>2 publications with TDO and Memory Disorders
Inflammation Antibodies	>2 publications with TDO and Inflammation
Lung Neoplasms Antibodies	>1 publications with TDO and Lung Neoplasms
Weight Loss Antibodies	>1 publications with TDO and Weight Loss
Kidney Diseases Antibodies	>1 publications with TDO and Kidney Diseases
Liver Diseases Antibodies	>1 publications with TDO and Liver Diseases

Organs/Tissues associated with TDO elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>11 publications with TDO and Brain
Blood Antibodies	>6 publications with TDO and Blood
Liver Antibodies	>6 publications with TDO and Liver
Heart Antibodies	>2 publications with TDO and Heart
Testis Antibodies	>1 publications with TDO and Testis
Connective Tissue Antibodies	>1 publications with TDO and Connective Tissue
Lung Antibodies	>1 publications with TDO and Lung
Embryonic Tissue Antibodies	>1 publications with TDO and Embryonic Tissue