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G Protein Coupled Receptor 37 (GPR37) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS760642

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. anti-Human GPR37 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Human GPR37 antibody was used as detection antibodies. The… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
G Protein Coupled Receptor 37 (GPR37), ELISA Kit
Full Product Name
Human G Protein Coupled Receptor 37 ELISA Kit
Product Gene Name
GPR37 elisa kit
Product Synonym Names
GPR37/ETBR-LP-1/PAELR/EDNRBL/Endothelin B receptor-like protein 1/G protein-coupled receptor 37 (endothelin receptor type B-like)/hET (B)R-LP/PAELRETBR-LP-1/Parkin-associated endothelin receptor-like receptor/probable G-protein coupled receptor 37
Species Reactivity
Human
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
0.156-10ng/ml
Sensitivity
0.094ng/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
67,114 Da
OMIM
602583
3D Structure
ModBase 3D Structure for O15354
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of GPR37 elisa kit

Human GPR37 ELISA Kit – Cat# MBS760642

Typical Standard Curve of GPR37 elisa kit

Human GPR37 ELISA Kit, Typical Standard Curve – Cat# MBS760642

Other Notes

Small volumes of GPR37 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GPR37 purchase

MBS760642 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the G Protein Coupled Receptor 37 (GPR37) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GPR37. The ELISA analytical biochemical technique of the MBS760642 kit is based on GPR37 antibody-GPR37 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GPR37 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GPR37. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for GPR37. It may not necessarily be applicable to this product.

NCBI GI #
3892879
NCBI GeneID
2861
NCBI Accession #
CAA73080.1
UniProt Primary Accession #
O15354
UniProt Secondary Accession #
O00348; O14768; Q8TD39; A4D0Y6
UniProt Related Accession #
O15354
NCBI Official Full Name
G protein coupled receptor 37
NCBI Official Synonym Full Names
G protein-coupled receptor 37 (endothelin receptor type B-like)
NCBI Official Symbol
GPR37
NCBI Official Synonym Symbols
PAELR; EDNRBL; hET(B)R-LP
UniProt Protein Name
Prosaposin receptor GPR37
UniProt Synonym Protein Names
Endothelin B receptor-like protein 1; ETBR-LP-1; G-protein coupled receptor 37; Parkin-associated endothelin receptor-like receptor; PAELR
Protein Family
Prosaposin receptor
UniProt Gene Name
GPR37
UniProt Synonym Gene Names
ETBR-LP-1; PAELR
UniProt Entry Name
GPR37_HUMAN
NCBI Protein Information
prosaposin receptor GPR37

NCBI Summary for GPR37

This gene is a member of the G protein-coupled receptor family. The encoded protein contains seven transmembrane domains and is found in cell and endoplasmic reticulum membranes. G protein-coupled receptors are involved in translating outside signals into G protein mediated intracellular effects. This gene product interacts with Parkin and is involved in juvenile Parkinson disease. [provided by RefSeq, Oct 2012]
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UniProt Comments for GPR37

GPR37: Orphan receptor. May have a unique functional role in the central nervous system. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q31

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to plasma membrane; plasma membrane; receptor complex; ubiquitin ligase complex

Molecular Function: G-protein coupled receptor activity; heat shock protein binding; Hsp70 protein binding; peptide binding; peptide receptor activity, G-protein coupled; protein binding; ubiquitin protein ligase binding

Biological Process: dopamine biosynthetic process; G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; locomotion during locomotory behavior; positive regulation of dopamine metabolic process; positive regulation of MAPKKK cascade
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Research Articles on GPR37

1. GPR37 was shown to be a component of the CASPR2-MUPP1 complex in brain.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GPR37 elisa kit

 Reference Product  PubMed Publications
 PARK2 elisa kit  >23 publications with GPR37 and PARK2
 SYVN1 elisa kit  >4 publications with GPR37 and SYVN1
 SEPT5 elisa kit  >2 publications with GPR37 and SEPT5

Pathways associated with GPR37 elisa kit

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Parkin-Ubiquitin Proteasomal System Pathway antibodies  Parkin-Ubiquitin Proteasomal System Pathway Diagram
 Parkinson's Disease Pathway antibodies  Parkinson's Disease Pathway Diagram
 Parkinsons Disease Pathway antibodies  Parkinsons Disease Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram

Diseases associated with GPR37 elisa kit

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >22 publications with GPR37 and Nervous System Diseases
 Disease Models, Animal Antibodies  >3 publications with GPR37 and Disease Models, Animal
 Nerve Degeneration Antibodies  >3 publications with GPR37 and Nerve Degeneration
 Liver Diseases Antibodies  >3 publications with GPR37 and Liver Diseases
 Multiple Myeloma Antibodies  >1 publications with GPR37 and Multiple Myeloma
 Fibrosis Antibodies  >1 publications with GPR37 and Fibrosis
 Atrophy Antibodies  >1 publications with GPR37 and Atrophy

Organs/Tissues associated with GPR37 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >31 publications with GPR37 and Brain
 Testis Antibodies  >2 publications with GPR37 and Testis
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