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Delta-Like Protein 1 (DLL1) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS760749

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti-Human DLL1antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Human DLL1 antibody was used as detection antibodies. The… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Delta-like protein 1 (DLL1), ELISA Kit
Full Product Name
Human Delta-like protein 1 ELISA Kit
Product Gene Name
DLL1 elisa kit
Product Synonym Names
DLL1 (Delta-like protein 1)
Species Reactivity
Human
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
31.25-2000pg/ml
Sensitivity
18.75pg/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
27,355 Da
OMIM
606582
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of DLL1 elisa kit

Human DLL1 ELISA Kit – Cat# MBS760749

Typical Standard Curve of DLL1 elisa kit

Human DLL1 ELISA Kit, Typical Standard Curve – Cat# MBS760749

Other Notes

Small volumes of DLL1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DLL1 purchase

MBS760749 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Delta-like protein 1 (DLL1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing DLL1. The ELISA analytical biochemical technique of the MBS760749 kit is based on DLL1 antibody-DLL1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DLL1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DLL1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for DLL1. It may not necessarily be applicable to this product.

NCBI GI #
110735443
NCBI GeneID
28514
NCBI Accession #
NP_005609.3
UniProt Secondary Accession #
Q9NU41; Q9UJV2; B2RAK7; B5M0B3
UniProt Related Accession #
O00548
GenBank Nucleotide #
NM_005618.3
NCBI Official Full Name
delta-like protein 1
NCBI Official Synonym Full Names
delta-like 1 (Drosophila)
NCBI Official Symbol
DLL1
NCBI Official Synonym Symbols
DL1; Delta; DELTA1
UniProt Protein Name
Delta-like protein 1
UniProt Synonym Protein Names
Drosophila Delta homolog 1; Delta1; H-Delta-1
Protein Family
Delta-like protein
UniProt Gene Name
DLL1
UniProt Synonym Gene Names
Delta1; H-Delta-1
UniProt Entry Name
DLL1_HUMAN
NCBI Protein Information
delta-like protein 1

NCBI Summary for DLL1

DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. [provided by RefSeq, Jul 2008]

UniProt Comments for DLL1

DLL1: Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. Interacts with Notch receptors. Expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney.

Protein type: Cell development/differentiation; Motility/polarity/chemotaxis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6q27

Cellular Component: adherens junction; apical plasma membrane; cytoplasmic vesicle; extracellular region; integral to plasma membrane; lipid raft; plasma membrane

Molecular Function: calcium ion binding; Notch binding; protein binding; Tat protein binding

Biological Process: astrocyte development; cell differentiation; cell fate determination; cerebellar molecular layer formation; cerebellar Purkinje cell layer structural organization; compartment specification; determination of left/right symmetry; heart looping; hemopoiesis; inner ear development; lateral inhibition; marginal zone B cell differentiation; negative regulation of auditory receptor cell differentiation; negative regulation of cell differentiation; negative regulation of cell proliferation; negative regulation of epidermal cell differentiation; negative regulation of epithelial cell differentiation; negative regulation of interleukin-10 production; negative regulation of myeloid cell differentiation; negative regulation of myoblast differentiation; negative regulation of neuron differentiation; neuron fate specification; Notch receptor processing; Notch signaling pathway; organ growth; positive regulation of cell proliferation; positive regulation of endocytosis; positive regulation of Notch signaling pathway; positive regulation of skeletal muscle growth; positive regulation of transcription from RNA polymerase II promoter; proximal/distal pattern formation; regulation of blood pressure; regulation of cell adhesion; regulation of cell division; regulation of growth; regulation of neurogenesis; regulation of skeletal muscle growth; regulation of somitogenesis; retina development in camera-type eye; retina morphogenesis in camera-type eye; skeletal muscle growth; somite specification; somitogenesis; spinal cord development
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Research Articles on DLL1

1. Although Delta1 activates signal transducer and activator of transcription 3 signaling similarly to the gp130-activating cytokine interleukin-6 (IL-6), it has opposite effects on myeloid cell production.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with DLL1 elisa kit

 Reference Product  PubMed Publications
 NOTCH1 elisa kit  >127 publications with DLL1 and NOTCH1
 NOTCH3 elisa kit  >22 publications with DLL1 and NOTCH3
 NOTCH4 elisa kit  >18 publications with DLL1 and NOTCH4
 MIB1 elisa kit  >5 publications with DLL1 and MIB1
 PSEN1 elisa kit  >3 publications with DLL1 and PSEN1
 ADAM12 elisa kit  >3 publications with DLL1 and ADAM12
 ADAM10 elisa kit  >3 publications with DLL1 and ADAM10

Pathways associated with DLL1 elisa kit

 Products by Pathway  Pathway Diagram
 Activated NOTCH1 Transmits Signal To The Nucleus Pathway antibodies  Activated NOTCH1 Transmits Signal To The Nucleus Pathway Diagram
 Constitutive Signaling By NOTCH1 HD Domain Mutants Pathway antibodies  Constitutive Signaling By NOTCH1 HD Domain Mutants Pathway Diagram
 Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway antibodies  Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway Diagram
 Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway antibodies  Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway Diagram
 Constitutive Signaling By NOTCH1 T(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Pathway antibodies  Constitutive Signaling By NOTCH1 T(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Pathway Diagram
 Delta-Notch Signaling Pathway antibodies  Delta-Notch Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Diseases Of Signal Transduction Pathway antibodies  Diseases Of Signal Transduction Pathway Diagram
 NOTCH2 Activation And Transmission Of Signal To The Nucleus Pathway antibodies  NOTCH2 Activation And Transmission Of Signal To The Nucleus Pathway Diagram
 Neural Crest Differentiation Pathway antibodies  Neural Crest Differentiation Pathway Diagram

Diseases associated with DLL1 elisa kit

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >13 publications with DLL1 and Carcinoma
 Congenital Abnormalities Antibodies  >12 publications with DLL1 and Congenital Abnormalities
 Disease Models, Animal Antibodies  >12 publications with DLL1 and Disease Models, Animal
 Inflammation Antibodies  >11 publications with DLL1 and Inflammation
 Immune System Diseases Antibodies  >11 publications with DLL1 and Immune System Diseases
 Lung Diseases Antibodies  >7 publications with DLL1 and Lung Diseases
 Abnormalities, Multiple Antibodies  >6 publications with DLL1 and Abnormalities, Multiple
 Neoplasms, Experimental Antibodies  >6 publications with DLL1 and Neoplasms, Experimental
 Necrosis Antibodies  >5 publications with DLL1 and Necrosis
 Neoplasm Metastasis Antibodies  >5 publications with DLL1 and Neoplasm Metastasis

Organs/Tissues associated with DLL1 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >43 publications with DLL1 and Embryonic Tissue
 Brain Antibodies  >41 publications with DLL1 and Brain
 Lung Antibodies  >17 publications with DLL1 and Lung
 Intestine Antibodies  >14 publications with DLL1 and Intestine
 Kidney Antibodies  >9 publications with DLL1 and Kidney
 Eye Antibodies  >7 publications with DLL1 and Eye
 Skin Antibodies  >6 publications with DLL1 and Skin
 Ear Antibodies  >5 publications with DLL1 and Ear
 Lymph Node Antibodies  >5 publications with DLL1 and Lymph Node
 Placenta Antibodies  >4 publications with DLL1 and Placenta
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