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Ciliary Neurotrophic Factor (CNTF) ELISA Kit for Chicken

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS761064

MBS761064 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Ciliary Neurotrophic Factor (CNTF) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Ciliary Neurotrophic Factor (CNTF), ELISA Kit
Full Product Name
Chicken Ciliary Neurotrophic Factor ELISA Kit
Product Gene Name
CNTF elisa kit
Species Reactivity
Chicken
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
62.5-4000pg/ml
Sensitivity
37.5pg/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
22,931 Da
OMIM
118945
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Standard Curve of CNTF elisa kit

Chicken CNTF ELISA Kit – Cat# MBS761064

Other Notes

Small volumes of CNTF elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CNTF. It may not necessarily be applicable to this product.

NCBI GI #
4758020
NCBI GeneID
1270
NCBI Accession #
NP_000605.1
UniProt Secondary Accession #
B2RAB2
UniProt Related Accession #
P26441
GenBank Nucleotide #
NM_000614.3
NCBI Official Full Name
ciliary neurotrophic factor
NCBI Official Synonym Full Names
ciliary neurotrophic factor
NCBI Official Symbol
CNTF
NCBI Official Synonym Symbols
HCNTF
UniProt Protein Name
Ciliary neurotrophic factor
Protein Family
Ciliary neurotrophic factor
UniProt Gene Name
CNTF
UniProt Synonym Gene Names
CNTF
UniProt Entry Name
CNTF_HUMAN
NCBI Protein Information
ciliary neurotrophic factor

NCBI Summary for CNTF

The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010]
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UniProt Comments for CNTF

CNTF: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. Belongs to the CNTF family.

Chromosomal Location of Human Ortholog: 11q12.2

Cellular Component: cytoplasm; extracellular region; extracellular space

Molecular Function: ciliary neurotrophic factor receptor binding; growth factor activity; interleukin-6 receptor binding; protein binding

Biological Process: growth; muscle morphogenesis; negative regulation of neuron apoptosis; negative regulation of photoreceptor cell differentiation; neuron development; positive regulation of cell proliferation; positive regulation of tyrosine phosphorylation of Stat3 protein; regulation of retinal cell programmed cell death; signal transduction
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Research Articles on CNTF

1. Human CNTF expression through lentiviral gene transfer in the rat striatum significantly decreased the levels of neuronal metabolites (N-acetyl-aspartate, N-acetyl-aspartyl-glutamate, and glutamate).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CNTF elisa kit

 Reference Product  PubMed Publications
 STAT3 elisa kit  >218 publications with CNTF and STAT3
 OSM elisa kit  >185 publications with CNTF and OSM
 LIFR elisa kit  >129 publications with CNTF and LIFR
 CNTFR elisa kit  >117 publications with CNTF and CNTFR
 IL6ST elisa kit  >112 publications with CNTF and IL6ST
 IL11 elisa kit  >73 publications with CNTF and IL11
 IL6 elisa kit  >16 publications with CNTF and IL6
 APOE elisa kit  >4 publications with CNTF and APOE
 IL6R elisa kit  >1 publications with CNTF and IL6R

Pathways associated with CNTF elisa kit

 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Delta-Notch Signaling Pathway antibodies  Delta-Notch Signaling Pathway Diagram
 IL-6-type Cytokine Receptor Ligand Interactions Pathway antibodies  IL-6-type Cytokine Receptor Ligand Interactions Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Interleukin-6 Family Signaling Pathway antibodies  Interleukin-6 Family Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Signaling By Interleukins Pathway antibodies  Signaling By Interleukins Pathway Diagram

Diseases associated with CNTF elisa kit

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >634 publications with CNTF and Nervous System Diseases
 Brain Diseases Antibodies  >316 publications with CNTF and Brain Diseases
 Disease Models, Animal Antibodies  >261 publications with CNTF and Disease Models, Animal
 Nerve Degeneration Antibodies  >198 publications with CNTF and Nerve Degeneration
 Inflammation Antibodies  >115 publications with CNTF and Inflammation
 Necrosis Antibodies  >92 publications with CNTF and Necrosis
 Weight Loss Antibodies  >76 publications with CNTF and Weight Loss
 Atrophy Antibodies  >70 publications with CNTF and Atrophy
 Movement Disorders Antibodies  >59 publications with CNTF and Movement Disorders
 Cognition Disorders Antibodies  >43 publications with CNTF and Cognition Disorders

Organs/Tissues associated with CNTF elisa kit

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1849 publications with CNTF and Nerve
 Brain Antibodies  >1332 publications with CNTF and Brain
 Eye Antibodies  >408 publications with CNTF and Eye
 Muscle Antibodies  >340 publications with CNTF and Muscle
 Embryonic Tissue Antibodies  >335 publications with CNTF and Embryonic Tissue
 Ganglia Antibodies  >332 publications with CNTF and Ganglia
 Spinal Cord Antibodies  >289 publications with CNTF and Spinal Cord
 Blood Antibodies  >218 publications with CNTF and Blood
 Bone Antibodies  >118 publications with CNTF and Bone
 Vascular Antibodies  >84 publications with CNTF and Vascular
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