General Transcription Factor IIH, Polypeptide 1 (GTF2H1) ELISA Kit for Mouse

GTF2H1: Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.

Protein type: Transcription initiation complex

Chromosomal Location of Human Ortholog: 11p15.1-p14

Cellular Component: holo TFIIH complex; nucleoplasm

Molecular Function: chromatin binding; DNA-dependent ATPase activity; protein binding; protein kinase activity; RNA polymerase subunit kinase activity

Biological Process: DNA repair; gene expression; mRNA capping; negative regulation of gene expression, epigenetic; nucleotide-excision repair; nucleotide-excision repair, DNA incision; positive regulation of transcription from RNA polymerase II promoter; positive regulation of viral transcription; protein amino acid phosphorylation; regulation of cyclin-dependent protein kinase activity; regulation of gene expression, epigenetic; RNA elongation from RNA polymerase I promoter; RNA elongation from RNA polymerase II promoter; termination of RNA polymerase I transcription; transcription from RNA polymerase I promoter; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase I promoter; transcription initiation from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair; viral reproduction