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Early Growth Response Protein 1 (EGR1) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS761554

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti-EGR1 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-EGR1 antibody was used as detection antibodies. The standards, test… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Early growth response protein 1 (EGR1), ELISA Kit
Full Product Name
Human Early growth response protein 1 ELISA Kit
Product Gene Name
EGR1 elisa kit
Product Synonym Names
EGR1/KROX24/NGFIA/ZNF225/AT225/Transcription factor ETR103/early growth response 1/early growth response protein 1/EGR-1/G0S30/KROX-24/Nerve growth factor-induced protein A/NGFI-A/Transcription factor Zif268/TIS8/ZIF-268/Zinc finger protein Krox-24/Zinc finger protein 225
Species Reactivity
Human
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
0.156-10ng/ml
Sensitivity
0.094ng/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
57,507 Da
OMIM
128990
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of EGR1 elisa kit

Human EGR1 ELISA Kit – Cat# MBS761554

Typical Standard Curve of EGR1 elisa kit

Human EGR1 ELISA Kit, Typical Standard Curve – Cat# MBS761554

Other Notes

Small volumes of EGR1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EGR1 purchase

MBS761554 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Early growth response protein 1 (EGR1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing EGR1. The ELISA analytical biochemical technique of the MBS761554 kit is based on EGR1 antibody-EGR1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect EGR1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, EGR1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for EGR1. It may not necessarily be applicable to this product.

NCBI GI #
4503493
NCBI GeneID
1958
NCBI Accession #
NP_001955.1
UniProt Related Accession #
P18146
GenBank Nucleotide #
NM_001964.2
NCBI Official Full Name
early growth response protein 1
NCBI Official Synonym Full Names
early growth response 1
NCBI Official Symbol
EGR1
NCBI Official Synonym Symbols
TIS8; AT225; G0S30; NGFI-A; ZNF225; KROX-24; ZIF-268
UniProt Protein Name
Early growth response protein 1
UniProt Synonym Protein Names
AT225; Nerve growth factor-induced protein A; NGFI-A; Transcription factor ETR103; Transcription factor Zif268; Zinc finger protein 225; Zinc finger protein Krox-24
Protein Family
Early growth response protein
UniProt Gene Name
EGR1
UniProt Synonym Gene Names
KROX24; ZNF225; EGR-1; NGFI-A
UniProt Entry Name
EGR1_HUMAN
NCBI Protein Information
early growth response protein 1

NCBI Summary for EGR1

The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014]
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UniProt Comments for EGR1

EGR1: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation. By growth factors. Belongs to the EGR C2H2-type zinc-finger protein family.

Protein type: C2H2-type zinc finger protein; Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 5q31.1

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: DNA binding; histone acetyltransferase binding; metal ion binding; protein binding; sequence-specific DNA binding; transcription factor activity

Biological Process: BMP signaling pathway; cytokine and chemokine mediated signaling pathway; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of apoptosis; regulation of protein sumoylation; response to glucose stimulus; response to insulin stimulus; T cell differentiation; transcription from RNA polymerase II promoter
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Research Articles on EGR1

1. These kinetic data with calf thymus DNA as a competitor suggested that there are millions of high-affinity quasi-specific sites for Egr-1 among the 3 billion bp of genomic DNA.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with EGR1 elisa kit

 Reference Product  PubMed Publications
 FOS elisa kit  >640 publications with EGR1 and FOS
 JUN elisa kit  >543 publications with EGR1 and JUN
 NAB2 elisa kit  >51 publications with EGR1 and NAB2
 PTEN elisa kit  >41 publications with EGR1 and PTEN
 TP53 elisa kit  >30 publications with EGR1 and TP53
 RELA elisa kit  >16 publications with EGR1 and RELA
 EP300 elisa kit  >5 publications with EGR1 and EP300
 SNAI1 elisa kit  >2 publications with EGR1 and SNAI1
 SUMO1 elisa kit  >2 publications with EGR1 and SUMO1
 NFATC2 elisa kit  >2 publications with EGR1 and NFATC2

Pathways associated with EGR1 elisa kit

 Products by Pathway  Pathway Diagram
 AGE-RAGE Signaling Pathway In Diabetic Complications antibodies  AGE-RAGE Signaling Pathway In Diabetic Complications Diagram
 AGE-RAGE Signaling Pathway In Diabetic Complications antibodies  AGE-RAGE Signaling Pathway In Diabetic Complications Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies  Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Downstream Signaling In Naive CD8+ T Cells Pathway antibodies  Downstream Signaling In Naive CD8+ T Cells Pathway Diagram
 ErbB1 Downstream Signaling Pathway antibodies  ErbB1 Downstream Signaling Pathway Diagram
 Glucocorticoid Receptor Regulatory Network Pathway antibodies  Glucocorticoid Receptor Regulatory Network Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram

Diseases associated with EGR1 elisa kit

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >199 publications with EGR1 and Nervous System Diseases
 Inflammation Antibodies  >178 publications with EGR1 and Inflammation
 Disease Models, Animal Antibodies  >163 publications with EGR1 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >155 publications with EGR1 and Cardiovascular Diseases
 Necrosis Antibodies  >137 publications with EGR1 and Necrosis
 Brain Diseases Antibodies  >129 publications with EGR1 and Brain Diseases
 Ischemia Antibodies  >76 publications with EGR1 and Ischemia
 Prostatic Neoplasms Antibodies  >65 publications with EGR1 and Prostatic Neoplasms
 Breast Neoplasms Antibodies  >63 publications with EGR1 and Breast Neoplasms
 Liver Diseases Antibodies  >59 publications with EGR1 and Liver Diseases

Organs/Tissues associated with EGR1 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >842 publications with EGR1 and Brain
 Blood Antibodies  >435 publications with EGR1 and Blood
 Nerve Antibodies  >288 publications with EGR1 and Nerve
 Vascular Antibodies  >265 publications with EGR1 and Vascular
 Muscle Antibodies  >218 publications with EGR1 and Muscle
 Lung Antibodies  >155 publications with EGR1 and Lung
 Liver Antibodies  >138 publications with EGR1 and Liver
 Kidney Antibodies  >137 publications with EGR1 and Kidney
 Bone Antibodies  >124 publications with EGR1 and Bone
 Prostate Antibodies  >81 publications with EGR1 and Prostate
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