Protachykinin-1 (TAC1) ELISA Kit for Human

Name: Human TAC1 ELISA Kit; Protachykinin-1; MyBioSource
Brand: MyBioSource
SKU: MBS761981
Price: 405 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS761981

Principle of the Assay: This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Capture antibody was pre-coated onto 96-well plates. And the biotin conjugated antibody was used as detection antibodies. The standards, test samples and… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Protachykinin-1 (TAC1), ELISA Kit

Full Product Name

Human Protachykinin-1 ELISA Kit

Product Gene Name

TAC1 elisa kit

Product Synonym Names

TAC1/Protachykinin-1/Tac1/Neurokinin-1/neurokinin 1/neurokinin 2/neurokinin A/neuromedin L; neurokinin alpha; neuropeptide K; neuropeptide gamma)/neuropeptide gamma/neuropeptide K/NK2/NKA/NKNAneurokinin alpha/NPK/PPT/protachykinin-1/substance K/substance P/TAC2neuromedin L/tachykinin 2/tachykinin; precursor 1/tachykinin; precursor 1 (substance K; substance P; neurokinin 1; neurokinin 2

Species Reactivity

Human

Assay Type

Sandwich ELISA, Double Antibody

Samples

Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples

Detection Range

4.688-300pg/ml

Sensitivity

2.813pg/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of TAC1. No significant cross-reactivity or interference between TAC1 and analogues was observed.

Preparation and Storage

Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C

Inter-assay Precision

CV<10%

Intra-assay Precision

CV<8%

Molecular Weight

11,376 Da

OMIM

162320

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of TAC1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TAC1 purchase

MBS761981 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Protachykinin-1 (TAC1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TAC1. The ELISA analytical biochemical technique of the MBS761981 kit is based on TAC1 antibody-TAC1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TAC1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TAC1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for TAC1. It may not necessarily be applicable to this product.

NCBI GI #

7770079

NCBI GeneID

6863

NCBI Accession #

NP_054704.1

UniProt Secondary Accession #

O60600; O60601; Q00072; Q53GH4; Q549V0; Q549V1; Q549V2; Q6FHM1

UniProt Related Accession #

P20366

GenBank Nucleotide #

NM_013998.2

NCBI Official Full Name

protachykinin-1 isoform delta

NCBI Official Synonym Full Names

tachykinin precursor 1

NCBI Official Symbol

TAC1

NCBI Official Synonym Symbols

NK2; NPK; NKNA; TAC2; Hs.2563

UniProt Protein Name

Protachykinin-1

UniProt Synonym Protein Names

PPT

Protein Family

Protachykinin

UniProt Gene Name

TAC1

UniProt Synonym Gene Names

NKA; NKNA; TAC2; NKA; NPK

UniProt Entry Name

TKN1_HUMAN

NCBI Protein Information

protachykinin-1

NCBI Summary for TAC1

This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]

UniProt Comments for TAC1

TAC1: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Belongs to the tachykinin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 7q21-q22

Cellular Component: axon; cell soma; cytosol; extracellular region; extracellular space; plasma membrane

Molecular Function: protein binding; receptor binding; substance P receptor binding

Biological Process: antibacterial humoral response; antifungal humoral response; associative learning; cell-cell signaling; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; detection of abiotic stimulus; elevation of cytosolic calcium ion concentration; inflammatory response; innate immune response; insemination; long-term memory; negative regulation of heart rate; neuropeptide signaling pathway; positive regulation of action potential; positive regulation of acute inflammatory response; positive regulation of lymphocyte proliferation; positive regulation of ossification; positive regulation of saliva secretion; positive regulation of stress fiber formation; positive regulation of synaptic transmission, cholinergic; positive regulation of synaptic transmission, GABAergic; regulation of blood pressure; response to hormone stimulus; response to lipopolysaccharide; response to morphine; response to pain; response to yeast; sensory perception of pain; synaptic transmission; tachykinin signaling pathway

Research Articles on TAC1

1. The spatial structures of human, mouse, and rat hemokinin-1 protein isoforms have been presented.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TAC1 elisa kit

Reference Product	PubMed Publications
TACR1 elisa kit	>35 publications with TAC1 and TACR1
TAC3 elisa kit	>8 publications with TAC1 and TAC3
TACR2 elisa kit	>7 publications with TAC1 and TACR2
TACR3 elisa kit	>6 publications with TAC1 and TACR3
NTS elisa kit	>3 publications with TAC1 and NTS
CCK elisa kit	>1 publications with TAC1 and CCK
NPS elisa kit	>1 publications with TAC1 and NPS

Pathways associated with TAC1 elisa kit

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
SIDS Susceptibility Pathways antibodies	SIDS Susceptibility Pathways Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram
Tachykinin Receptors Bind Tachykinins Pathway antibodies	Tachykinin Receptors Bind Tachykinins Pathway Diagram

Diseases associated with TAC1 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>24 publications with TAC1 and Inflammation
Nervous System Diseases Antibodies	>23 publications with TAC1 and Nervous System Diseases
Pain Antibodies	>20 publications with TAC1 and Pain
Disease Models, Animal Antibodies	>15 publications with TAC1 and Disease Models, Animal
Hyperalgesia Antibodies	>8 publications with TAC1 and Hyperalgesia
Neurogenic Inflammation Antibodies	>5 publications with TAC1 and Neurogenic Inflammation
Schizophrenia Antibodies	>5 publications with TAC1 and Schizophrenia
Bipolar Disorder Antibodies	>5 publications with TAC1 and Bipolar Disorder
Necrosis Antibodies	>5 publications with TAC1 and Necrosis
Hypersensitivity Antibodies	>3 publications with TAC1 and Hypersensitivity

Organs/Tissues associated with TAC1 elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>39 publications with TAC1 and Brain
Nerve Antibodies	>18 publications with TAC1 and Nerve
Embryonic Tissue Antibodies	>4 publications with TAC1 and Embryonic Tissue
Eye Antibodies	>3 publications with TAC1 and Eye
Connective Tissue Antibodies	>1 publications with TAC1 and Connective Tissue
Uncharacterized Tissue Antibodies	>1 publications with TAC1 and Uncharacterized Tissue
Kidney Antibodies	>1 publications with TAC1 and Kidney