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Protein Transport Protein Sec23b (SEC23B) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS762355

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. anti-Human Sec23b antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Human Sec23b antibody was used as detection antibodies. The… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
protein transport protein Sec23B, ELISA Kit
Full Product Name
Human protein transport protein Sec23B ELISA Kit
Product Gene Name
Sec23b elisa kit
Product Synonym Names
Sec23b/SEC23-related protein B/SEC23B
Species Reactivity
Human
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
0.156-10ng/ml
Sensitivity
0.094ng/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
86,479 Da
OMIM
224100
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of Sec23b elisa kit

Human SEC23B ELISA Kit – Cat# MBS762355

Typical Standard Curve of Sec23b elisa kit

Human SEC23B ELISA Kit, Typical Standard Curve – Cat# MBS762355

Other Notes

Small volumes of Sec23b elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Sec23b purchase

MBS762355 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the protein transport protein Sec23B, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Sec23b. The ELISA analytical biochemical technique of the MBS762355 kit is based on Sec23b antibody-Sec23b antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Sec23b antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Sec23b. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for Sec23b. It may not necessarily be applicable to this product.

NCBI GI #
289629267
NCBI GeneID
10483
NCBI Accession #
NP_001166217.1
UniProt Secondary Accession #
Q503A9; Q5W183; Q9BS15; Q9BSI2; Q9H1D7; D3DW33
UniProt Related Accession #
Q15437
GenBank Nucleotide #
NM_001172746.1
NCBI Official Full Name
protein transport protein Sec23B isoform 2
NCBI Official Synonym Full Names
Sec23 homolog B, COPII coat complex component
NCBI Official Symbol
SEC23B
NCBI Official Synonym Symbols
CDAII; CDAN2; CDA-II; HEMPAS
UniProt Protein Name
Protein transport protein Sec23B
UniProt Synonym Protein Names
SEC23-related protein B
Protein Family
Protein transport protein
UniProt Gene Name
SEC23B
UniProt Entry Name
SC23B_HUMAN
NCBI Protein Information
protein transport protein Sec23B

NCBI Summary for Sec23b

The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010]
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UniProt Comments for Sec23b

SEC23B: Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex. COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1. Belongs to the SEC23/SEC24 family. SEC23 subfamily.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 20p11.23

Cellular Component: COPII vesicle coat; endomembrane system; endoplasmic reticulum membrane; ER-Golgi intermediate compartment membrane; Golgi membrane; intracellular membrane-bound organelle; membrane; perinuclear region of cytoplasm

Molecular Function: protein binding; zinc ion binding

Biological Process: ER to Golgi vesicle-mediated transport; intracellular protein transport; vesicle-mediated transport

Disease: Anemia, Congenital Dyserythropoietic, Type Ii
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Research Articles on Sec23b

1. Congenital dyserythropoietic anemia, type II with SEC23B exon 12 c.1385 A --> G mutation, and pseudo-Gaucher cells in two siblings has been described.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Sec23b elisa kit

 Reference Product  PubMed Publications
 SEC13 elisa kit  >4 publications with Sec23b and SEC13
 SEC24C elisa kit  >2 publications with Sec23b and SEC24C
 SEC24D elisa kit  >2 publications with Sec23b and SEC24D
 SEC24B elisa kit  >1 publications with Sec23b and SEC24B
 SAR1B elisa kit  >1 publications with Sec23b and SAR1B
 SEC31A elisa kit  >1 publications with Sec23b and SEC31A

Pathways associated with Sec23b elisa kit

 Products by Pathway  Pathway Diagram
 COPII Complex Pathway antibodies  COPII Complex Pathway Diagram
 COPII Complex Pathway antibodies  COPII Complex Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 SREBP Signalling Pathway antibodies  SREBP Signalling Pathway Diagram

Diseases associated with Sec23b elisa kit

 Disease Name  Pubmed Publications
 Anemia, Dyserythropoietic, Congenital Antibodies  >35 publications with Sec23b and Anemia, Dyserythropoietic, Congenital
 Hyperplasia Antibodies  >4 publications with Sec23b and Hyperplasia
 Liver Diseases Antibodies  >2 publications with Sec23b and Liver Diseases
 Immune System Diseases Antibodies  >2 publications with Sec23b and Immune System Diseases
 Edema Antibodies  >1 publications with Sec23b and Edema
 Disease Models, Animal Antibodies  >1 publications with Sec23b and Disease Models, Animal
 Liver Cirrhosis Antibodies  >1 publications with Sec23b and Liver Cirrhosis
 Carcinoma, Hepatocellular Antibodies  >1 publications with Sec23b and Carcinoma, Hepatocellular
 Fibrosis Antibodies  >1 publications with Sec23b and Fibrosis
 Liver Neoplasms Antibodies  >1 publications with Sec23b and Liver Neoplasms

Organs/Tissues associated with Sec23b elisa kit

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >21 publications with Sec23b and Blood
 Bone Antibodies  >16 publications with Sec23b and Bone
 Bone Marrow Antibodies  >13 publications with Sec23b and Bone Marrow
 Embryonic Tissue Antibodies  >4 publications with Sec23b and Embryonic Tissue
 Liver Antibodies  >3 publications with Sec23b and Liver
 Pancreas Antibodies  >3 publications with Sec23b and Pancreas
 Connective Tissue Antibodies  >2 publications with Sec23b and Connective Tissue
 Thyroid Antibodies  >1 publications with Sec23b and Thyroid
 Placenta Antibodies  >1 publications with Sec23b and Placenta
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