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Paired Immunoglobulin-Like Type 2 Receptor Beta (PILRB) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS762765

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti-Human PILRBantibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Human PILRB antibody was used as detection antibodies. The… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Paired immunoglobulin-like type 2 receptor beta (PILRB), ELISA Kit
Full Product Name
Human Paired immunoglobulin-like type 2 receptor beta ELISA Kit
Product Gene Name
PILRB elisa kit
Product Synonym Names
PILRB/FDFACT/FDFACT1/FDFACT2/activating receptor PILRbeta/Activating receptor PILR-beta/Cell surface receptor FDFACT/cell surface receptor FDFACT1/cell surface receptor FDFACT2/paired immunoglobin-like receptor beta/paired immunoglobin-like type 2 receptor beta/paired immunoglobulin-like receptor beta/paired immunoglobulin-like type 2 receptor beta
Species Reactivity
Human
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
0.156-10ng/ml
Sensitivity
0.094ng/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
29,630 Da
OMIM
605342
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of PILRB elisa kit

Human PILRB ELISA Kit – Cat# MBS762765

Typical Standard Curve of PILRB elisa kit

Human PILRB ELISA Kit, Typical Standard Curve – Cat# MBS762765

Other Notes

Small volumes of PILRB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PILRB purchase

MBS762765 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Paired immunoglobulin-like type 2 receptor beta (PILRB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PILRB. The ELISA analytical biochemical technique of the MBS762765 kit is based on PILRB antibody-PILRB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PILRB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PILRB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for PILRB. It may not necessarily be applicable to this product.

NCBI GI #
30179911
NCBI GeneID
29990
NCBI Accession #
NP_839956.1
UniProt Secondary Accession #
Q69YF9; Q9HBS0
UniProt Related Accession #
Q9UKJ0
GenBank Nucleotide #
NM_178238.3
NCBI Official Full Name
paired immunoglobulin-like type 2 receptor beta
NCBI Official Synonym Full Names
paired immunoglobin-like type 2 receptor beta
NCBI Official Symbol
PILRB
NCBI Official Synonym Symbols
FDFACT1; FDFACT2
UniProt Protein Name
Paired immunoglobulin-like type 2 receptor beta
UniProt Synonym Protein Names
Activating receptor PILR-beta; Cell surface receptor FDFACT
Protein Family
Paired immunoglobulin-like type 2 receptor
UniProt Gene Name
PILRB
UniProt Synonym Gene Names
FDFACT
UniProt Entry Name
PILRB_HUMAN
NCBI Protein Information
paired immunoglobulin-like type 2 receptor beta

NCBI Summary for PILRB

The paired immunoglobin-like type 2 receptors consist of highly related activating and inhibitory receptors that are involved in the regulation of many aspects of the immune system. The paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This gene encodes the activating member of the receptor pair and contains a truncated cytoplasmic tail relative to its inhibitory counterpart (PILRA), that has a long cytoplasmic tail with immunoreceptor tyrosine-based inhibitory (ITIM) motifs. This gene is thought to have arisen from a duplication of the inhibitory PILRA gene and evolved to acquire its activating function. [provided by RefSeq, Jun 2013]
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UniProt Comments for PILRB

PILRB: Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: integral to plasma membrane

Molecular Function: MHC class I protein binding; protein binding

Biological Process: transmembrane receptor protein tyrosine kinase activation (dimerization); transmembrane receptor protein tyrosine kinase signaling pathway
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Research Articles on PILRB

1. PILRbeta differs from PILRalpha in one of the three residues (Y2, R95 and W108) on the surface of PILRalpha (L108), explaining its inability to engage gB.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PILRB elisa kit

 Reference Product  PubMed Publications
 PTPN6 elisa kit  >1 publications with PILRB and PTPN6
 PTPN11 elisa kit  >1 publications with PILRB and PTPN11

Pathways associated with PILRB elisa kit

 Products by Pathway  Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 IL-3 Signaling Pathway antibodies  IL-3 Signaling Pathway Diagram

Diseases associated with PILRB elisa kit

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >2 publications with PILRB and Necrosis
 Inflammation Antibodies  >2 publications with PILRB and Inflammation
 Lymphoma Antibodies  >1 publications with PILRB and Lymphoma
 Nervous System Diseases Antibodies  >1 publications with PILRB and Nervous System Diseases
 Immune System Diseases Antibodies  >1 publications with PILRB and Immune System Diseases

Organs/Tissues associated with PILRB elisa kit

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with PILRB and Blood
 Bone Marrow Antibodies  >1 publications with PILRB and Bone Marrow
 Lung Antibodies  >1 publications with PILRB and Lung
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