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Pituitary Adenylate Cyclase-Activating Polypeptide Type 1 Receptor (ADCYAP1R1) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS762897

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti-Human ADCYAP1R1 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Human ADCYAP1R1 antibody was used as detection antibodies.… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Pituitary adenylate cyclase-activating polypeptide type I receptor (ADCYAP1R1), ELISA Kit
Full Product Name
Human Pituitary adenylate cyclase-activating polypeptide type I receptor ELISA Kit
Product Gene Name
ADCYAP1R1 elisa kit
Product Synonym Names
ADCYAP1R1/Pituitary adenylate cyclase-activating polypeptide type I receptor/PACAP type I receptor/PACAP-R-1/PACAP-R1/PAC1/PAC1R/PACAPR/PACAPRI
Species Reactivity
Human
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
0.156-10ng/ml
Sensitivity
0.094ng/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
53,233 Da
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of ADCYAP1R1 elisa kit

Human ADCYAP1R1 ELISA Kit – Cat# MBS762897

Typical Standard Curve of ADCYAP1R1 elisa kit

Human ADCYAP1R1 ELISA Kit, Typical Standard Curve – Cat# MBS762897

Other Notes

Small volumes of ADCYAP1R1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ADCYAP1R1 purchase

MBS762897 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Pituitary adenylate cyclase-activating polypeptide type I receptor (ADCYAP1R1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ADCYAP1R1. The ELISA analytical biochemical technique of the MBS762897 kit is based on ADCYAP1R1 antibody-ADCYAP1R1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ADCYAP1R1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ADCYAP1R1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for ADCYAP1R1. It may not necessarily be applicable to this product.

NCBI GI #
396080323
NCBI GeneID
24167
NCBI Accession #
NP_001257508.1
UniProt Secondary Accession #
Q63414
UniProt Related Accession #
P32215
GenBank Nucleotide #
NM_001270579.1
NCBI Official Full Name
pituitary adenylate cyclase-activating polypeptide type I receptor isoform a
NCBI Official Synonym Full Names
adenylate cyclase activating polypeptide 1 receptor type 1
NCBI Official Symbol
Adcyap1r1
NCBI Official Synonym Symbols
PAC1-R; PACAPR1; PACAP-R1; PACAPR1A; PACAP-R1A
UniProt Protein Name
Pituitary adenylate cyclase-activating polypeptide type I receptor
Protein Family
Pituitary adenylate cyclase-activating polypeptide type I receptor
UniProt Gene Name
Adcyap1r1
UniProt Synonym Gene Names
PACAP type I receptor; PACAP-R-1; PACAP-R1
UniProt Entry Name
PACR_RAT
NCBI Protein Information
pituitary adenylate cyclase-activating polypeptide type I receptor

NCBI Summary for ADCYAP1R1

regulates neural precursor proliferation; mediates inhibitory signaling for Shh-induced cerebellar granule precursor cell proliferation [RGD, Feb 2006]

UniProt Comments for ADCYAP1R1

ADCYAP1R1: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. Belongs to the G-protein coupled receptor 2 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 2

Cellular Component: caveola; cell surface; cytoplasm; endosome; Golgi membrane; integral to membrane; neuron projection; receptor complex; rough endoplasmic reticulum; tight junction

Molecular Function: adenylate cyclase binding; ADP-ribosylation factor binding; neuropeptide binding; vasoactive intestinal polypeptide receptor activity

Biological Process: cAMP-mediated signaling; cell differentiation; cell surface receptor linked signal transduction; development of primary female sexual characteristics; G-protein coupled receptor protein signaling pathway; multicellular organismal response to stress; phospholipase C activation; positive regulation of cAMP biosynthetic process; response to drug; response to estradiol stimulus; response to ethanol; spermatogenesis
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Research Articles on ADCYAP1R1

1. Compared to the rats in the control group, the rats in the HF group had the expression levels of 12 genes with significant changes, Agrp, Ghrl, and Nr3c1, Apoa4, Cntf, Ghr, IL-1beta, Ins1, Lepr,Sort, Adcyap1r1 and Adrb1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ADCYAP1R1 elisa kit

 Reference Product  PubMed Publications
 Adcyap1 elisa kit  >104 publications with ADCYAP1R1 and Adcyap1
 Plagl1 elisa kit  >2 publications with ADCYAP1R1 and Plagl1

Pathways associated with ADCYAP1R1 elisa kit

 Products by Pathway  Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class B Secretin-like Pathway antibodies  GPCRs, Class B Secretin-like Pathway Diagram
 Glucagon-type Ligand Receptors Pathway antibodies  Glucagon-type Ligand Receptors Pathway Diagram
 Insulin Secretion Pathway antibodies  Insulin Secretion Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with ADCYAP1R1 elisa kit

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >6 publications with ADCYAP1R1 and Breast Neoplasms
 Lung Neoplasms Antibodies  >6 publications with ADCYAP1R1 and Lung Neoplasms
 Inflammation Antibodies  >5 publications with ADCYAP1R1 and Inflammation
 Immune System Diseases Antibodies  >3 publications with ADCYAP1R1 and Immune System Diseases
 Kidney Diseases Antibodies  >3 publications with ADCYAP1R1 and Kidney Diseases
 Asthma Antibodies  >3 publications with ADCYAP1R1 and Asthma
 Liver Neoplasms Antibodies  >2 publications with ADCYAP1R1 and Liver Neoplasms
 Hyperplasia Antibodies  >2 publications with ADCYAP1R1 and Hyperplasia
 Hypertrophy Antibodies  >2 publications with ADCYAP1R1 and Hypertrophy
 Liver Neoplasms, Experimental Antibodies  >2 publications with ADCYAP1R1 and Liver Neoplasms, Experimental
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