Neuropeptide Y Receptor Y2 (NPYR2) ELISA Kit for Human

Name: Human NPYR2 ELISA Kit; Neuropeptide Y Receptor Y2; MyBioSource
Brand: MyBioSource
SKU: MBS762919
Price: 405 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS762919

Principle of the Assay: This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Capture antibody was pre-coated onto 96-well plates. And the biotin conjugated antibody was used as detection antibodies. The standards, test samples and… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Neuropeptide Y Receptor Y2 (NPYR2), ELISA Kit

Full Product Name

Human Neuropeptide Y Receptor Y2 ELISA Kit

Product Gene Name

NPYR2 elisa kit

Product Synonym Names

NPYR2

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, plasma, tissue homogenates and other biological fluids

Detection Range

0.313-20ng/ml

Sensitivity

0.188ng/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of NPYR2. No significant cross-reactivity or interference between NPYR2 and analogues was observed.

Preparation and Storage

Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C

Inter-assay Precision

CV<10%

Intra-assay Precision

CV<8%

Molecular Weight

42,731 Da

OMIM

162642

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of NPYR2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NPYR2 purchase

MBS762919 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Neuropeptide Y Receptor Y2 (NPYR2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NPYR2. The ELISA analytical biochemical technique of the MBS762919 kit is based on NPYR2 antibody-NPYR2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NPYR2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NPYR2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for NPYR2. It may not necessarily be applicable to this product.

NCBI GI #

29824918

NCBI GeneID

4887

NCBI Accession #

AAO92062.1

UniProt Secondary Accession #

Q13281; Q13457; Q4W5G7; Q6AZZ6; Q9UE67

UniProt Related Accession #

P49146

NCBI Official Full Name

neuropeptide Y receptor Y2

NCBI Official Synonym Full Names

neuropeptide Y receptor Y2

NCBI Official Symbol

NPY2R

NCBI Official Synonym Symbols

NPY2-R

UniProt Protein Name

Neuropeptide Y receptor type 2

UniProt Synonym Protein Names

NPY-Y2 receptor; Y2 receptor

UniProt Gene Name

NPY2R

UniProt Synonym Gene Names

NPY2-R; Y2 receptor

UniProt Entry Name

NPY2R_HUMAN

NCBI Protein Information

neuropeptide Y receptor type 2

UniProt Comments for NPYR2

NPY2R: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu- 31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1

Chromosomal Location of Human Ortholog: 4q31

Cellular Component: cytosol; integral to plasma membrane; nonmotile primary cilium; plasma membrane

Molecular Function: calcium channel regulator activity; neuropeptide Y receptor activity; peptide YY receptor activity; protein binding; receptor activity

Biological Process: behavioral fear response; cell surface receptor linked signal transduction; elevation of cytosolic calcium ion concentration; feeding behavior; G-protein signaling, adenylate cyclase inhibiting pathway; locomotory behavior; negative regulation of cAMP biosynthetic process; negative regulation of neurological process; negative regulation of secretion; negative regulation of synaptic transmission, glutamatergic; neuropeptide signaling pathway; nitric oxide mediated signal transduction; positive regulation of circadian sleep/wake cycle, non-REM sleep; positive regulation of dopamine secretion; positive regulation of peptide secretion; positive regulation of smooth muscle contraction; regulation of sensory perception of pain; secretion

Research Articles on NPYR2

1. Data show that the Y2-receptor high expression G allele is associated with a less efficient mode of action cascading where different task goals are activated in parallel.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NPYR2 elisa kit

Reference Product	PubMed Publications
NPY elisa kit	>20 publications with NPYR2 and NPY
NPY1R elisa kit	>15 publications with NPYR2 and NPY1R
NPY5R elisa kit	>13 publications with NPYR2 and NPY5R
PYY elisa kit	>6 publications with NPYR2 and PYY
PPY elisa kit	>2 publications with NPYR2 and PPY
NMU elisa kit	>1 publications with NPYR2 and NMU
POMC elisa kit	>1 publications with NPYR2 and POMC

Pathways associated with NPYR2 elisa kit

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Peptide GPCRs Pathway antibodies	Peptide GPCRs Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram

Diseases associated with NPYR2 elisa kit

Disease Name	Pubmed Publications
Brain Diseases Antibodies	>3 publications with NPYR2 and Brain Diseases
Abnormalities, Multiple Antibodies	>2 publications with NPYR2 and Abnormalities, Multiple
Alcoholism Antibodies	>2 publications with NPYR2 and Alcoholism
Hypertension Antibodies	>2 publications with NPYR2 and Hypertension
Edema Antibodies	>1 publications with NPYR2 and Edema
Cognition Disorders Antibodies	>1 publications with NPYR2 and Cognition Disorders
Hypertrophy Antibodies	>1 publications with NPYR2 and Hypertrophy
Cardiomegaly Antibodies	>1 publications with NPYR2 and Cardiomegaly
Neurobehavioral Manifestations Antibodies	>1 publications with NPYR2 and Neurobehavioral Manifestations
Epilepsy Antibodies	>1 publications with NPYR2 and Epilepsy

Organs/Tissues associated with NPYR2 elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>13 publications with NPYR2 and Brain
Nerve Antibodies	>3 publications with NPYR2 and Nerve