Extracellular Sulfatase Sulf-2 (SULF2) ELISA Kit for Human

Name: Human SULF2 ELISA Kit; Extracellular Sulfatase Sulf-2; MyBioSource
Brand: MyBioSource
SKU: MBS762970
Price: 405 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS762970

Principle of the Assay: This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Capture antibody was pre-coated onto 96-well plates. And the biotin conjugated antibody was used as detection antibodies. The standards, test samples and… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Extracellular sulfatase Sulf-2 (SULF2), ELISA Kit

Full Product Name

Human Extracellular sulfatase Sulf-2 ELISA Kit

Product Gene Name

SULF2 elisa kit

Product Synonym Names

SULF2/extracellular sulfatase Sulf-2/SULF-2/sulfatase 2/hSulf-2

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, plasma, tissue homogenates and other biological fluids

Detection Range

0.313-20ng/ml

Sensitivity

0.188ng/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of SULF2. No significant crossreactivity or interference between SULF2 and analogues was observed.

Preparation and Storage

Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C

Inter-assay Precision

CV<10%

Intra-assay Precision

CV<8%

Molecular Weight

100,156 Da

OMIM

610013

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of SULF2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SULF2 purchase

MBS762970 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Extracellular sulfatase Sulf-2 (SULF2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SULF2. The ELISA analytical biochemical technique of the MBS762970 kit is based on SULF2 antibody-SULF2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SULF2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SULF2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for SULF2. It may not necessarily be applicable to this product.

NCBI GI #

29789100

NCBI GeneID

55959

NCBI Accession #

NP_061325.1

UniProt Secondary Accession #

Q5JYE1; Q6UX86; Q96SG2; Q9H1H0; Q9UJR3; Q9ULH3; E1P5U6

UniProt Related Accession #

Q8IWU5

GenBank Nucleotide #

NM_018837.3

NCBI Official Full Name

extracellular sulfatase Sulf-2 isoform a

NCBI Official Synonym Full Names

sulfatase 2

NCBI Official Symbol

SULF2

NCBI Official Synonym Symbols

HSULF-2

UniProt Protein Name

Extracellular sulfatase Sulf-2

Protein Family

Extracellular sulfatase

UniProt Gene Name

SULF2

UniProt Synonym Gene Names

KIAA1247; hSulf-2

UniProt Entry Name

SULF2_HUMAN

NCBI Protein Information

extracellular sulfatase Sulf-2

NCBI Summary for SULF2

Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008]

UniProt Comments for SULF2

SULF2: Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; EC 3.1.6.-; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 20q13.12

Cellular Component: cell surface; endoplasmic reticulum; extracellular space; Golgi stack; plasma membrane

Molecular Function: arylsulfatase activity; calcium ion binding; N-acetylglucosamine-6-sulfatase activity

Biological Process: cartilage development; chondrocyte development; embryonic skeletal development; esophagus smooth muscle contraction; glomerular basement membrane development; glomerular filtration; heparan sulfate proteoglycan metabolic process; kidney development; negative regulation of fibroblast growth factor receptor signaling pathway; positive regulation of Wnt receptor signaling pathway

Research Articles on SULF2

1. Results show that SULF1 or SULF2 overexpression contributes to colorectal cancer cell proliferation, migration, and invasion.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SULF2 elisa kit

Reference Product	PubMed Publications
HS6ST1 elisa kit	>3 publications with SULF2 and HS6ST1
HS6ST2 elisa kit	>2 publications with SULF2 and HS6ST2
HS6ST3 elisa kit	>1 publications with SULF2 and HS6ST3
ARSG elisa kit	>1 publications with SULF2 and ARSG

Diseases associated with SULF2 elisa kit

Disease Name	Pubmed Publications
Adenocarcinoma Antibodies	>21 publications with SULF2 and Adenocarcinoma
Carcinoma, Hepatocellular Antibodies	>13 publications with SULF2 and Carcinoma, Hepatocellular
Liver Neoplasms Antibodies	>10 publications with SULF2 and Liver Neoplasms
Breast Neoplasms Antibodies	>9 publications with SULF2 and Breast Neoplasms
Liver Diseases Antibodies	>9 publications with SULF2 and Liver Diseases
Lung Neoplasms Antibodies	>8 publications with SULF2 and Lung Neoplasms
Disease Models, Animal Antibodies	>6 publications with SULF2 and Disease Models, Animal
Neoplasms, Experimental Antibodies	>4 publications with SULF2 and Neoplasms, Experimental
Fibrosis Antibodies	>4 publications with SULF2 and Fibrosis
Cardiovascular Diseases Antibodies	>3 publications with SULF2 and Cardiovascular Diseases

Organs/Tissues associated with SULF2 elisa kit

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>19 publications with SULF2 and Liver
Lung Antibodies	>16 publications with SULF2 and Lung
Brain Antibodies	>16 publications with SULF2 and Brain
Embryonic Tissue Antibodies	>12 publications with SULF2 and Embryonic Tissue
Bone Antibodies	>11 publications with SULF2 and Bone
Blood Antibodies	>11 publications with SULF2 and Blood
Vascular Antibodies	>9 publications with SULF2 and Vascular
Muscle Antibodies	>7 publications with SULF2 and Muscle
Stomach Antibodies	>5 publications with SULF2 and Stomach
Kidney Antibodies	>5 publications with SULF2 and Kidney