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Metallothionein 3 (MT3) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS763035

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. anti-Human MT3 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Human MT3 antibody was used as detection antibodies. The… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Metallothionein 3 (MT3), ELISA Kit
Full Product Name
Human Metallothionein 3 ELISA Kit
Product Gene Name
MT3 elisa kit
Product Synonym Names
MT3/Metallothionein 3
Species Reactivity
Human
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
0.156-10ng/ml
Sensitivity
0.094ng/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
6,927 Da
OMIM
139255
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of MT3 elisa kit

Human MT3 ELISA Kit – Cat# MBS763035

Typical Standard Curve of MT3 elisa kit

Human MT3 ELISA Kit, Typical Standard Curve – Cat# MBS763035

Other Notes

Small volumes of MT3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MT3 purchase

MBS763035 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Metallothionein 3 (MT3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MT3. The ELISA analytical biochemical technique of the MBS763035 kit is based on MT3 antibody-MT3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MT3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MT3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for MT3. It may not necessarily be applicable to this product.

NCBI GI #
15341818
NCBI GeneID
4504
NCBI Accession #
AAH13081.1
UniProt Secondary Accession #
Q2V574
UniProt Related Accession #
P25713
NCBI Official Full Name
Metallothionein 3
NCBI Official Synonym Full Names
metallothionein 3
NCBI Official Symbol
MT3
NCBI Official Synonym Symbols
GIF; GIFB; GRIF; ZnMT3
UniProt Protein Name
Metallothionein-3
UniProt Synonym Protein Names
GIFB; GIF; Growth inhibitory factor; Metallothionein-III; MT-III
Protein Family
Metallothionein
UniProt Gene Name
MT3
UniProt Synonym Gene Names
MT-3; GIF; MT-III
UniProt Entry Name
MT3_HUMAN
NCBI Protein Information
metallothionein-3

UniProt Comments for MT3

MT3: Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro. Belongs to the metallothionein superfamily. Type 1 family.

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: axon; cytoplasm; cytosol; dendritic spine; extracellular space; inclusion body; intracellular; microtubule; mitochondrial outer membrane; perinuclear region of cytoplasm; plasma membrane; postsynaptic density; ribosome; rough endoplasmic reticulum; synaptic vesicle

Molecular Function: antioxidant activity; cadmium ion binding; caspase inhibitor activity; copper ion binding; drug binding; protein binding; protein kinase activator activity; zinc ion binding

Biological Process: activation of protein kinase B; astrocyte development; brain development; cadmium ion homeostasis; cell proliferation; cellular lipid catabolic process; cellular metal ion homeostasis; cellular zinc ion homeostasis; cholesterol catabolic process; energy reserve metabolic process; histone modification; leptin-mediated signaling pathway; negative regulation of apoptosis; negative regulation of autophagy; negative regulation of axon extension; negative regulation of caspase activity; negative regulation of cell growth; negative regulation of neuron apoptosis; negative regulation of oxidoreductase activity; negative regulation of transcription, DNA-dependent; positive regulation of catalytic activity; positive regulation of protein amino acid phosphorylation; positive regulation of transcription, DNA-dependent; positive regulation of vascular endothelial growth factor receptor signaling pathway; protein import into nucleus, translocation; protein kinase B signaling cascade; protein stabilization; regulation of protein amino acid glycosylation; regulation of response to food; removal of superoxide radicals; response to hypoxia; response to metal ion; zinc ion homeostasis; zinc ion transport
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Research Articles on MT3

1. MT3 may regulate breast cancer cell invasiveness by modulating the expression of MMP3.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MT3 elisa kit

 Reference Product  PubMed Publications
 MT4 elisa kit  >56 publications with MT3 and MT4
 MT1A elisa kit  >9 publications with MT3 and MT1A
 SLC30A3 elisa kit  >2 publications with MT3 and SLC30A3
 TTR elisa kit  >1 publications with MT3 and TTR
 KRT4 elisa kit  >1 publications with MT3 and KRT4

Pathways associated with MT3 elisa kit

 Products by Pathway  Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metallothioneins Bind Metals Pathway antibodies  Metallothioneins Bind Metals Pathway Diagram
 Response To Metal Ions Pathway antibodies  Response To Metal Ions Pathway Diagram

Diseases associated with MT3 elisa kit

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >29 publications with MT3 and Nervous System Diseases
 Immune System Diseases Antibodies  >26 publications with MT3 and Immune System Diseases
 Neoplasm Metastasis Antibodies  >22 publications with MT3 and Neoplasm Metastasis
 Death Antibodies  >20 publications with MT3 and Death
 Brain Diseases Antibodies  >18 publications with MT3 and Brain Diseases
 Neoplasm Invasiveness Antibodies  >17 publications with MT3 and Neoplasm Invasiveness
 Inflammation Antibodies  >13 publications with MT3 and Inflammation
 Breast Neoplasms Antibodies  >13 publications with MT3 and Breast Neoplasms
 Cardiovascular Diseases Antibodies  >12 publications with MT3 and Cardiovascular Diseases
 Lung Neoplasms Antibodies  >9 publications with MT3 and Lung Neoplasms

Organs/Tissues associated with MT3 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >73 publications with MT3 and Brain
 Eye Antibodies  >14 publications with MT3 and Eye
 Connective Tissue Antibodies  >13 publications with MT3 and Connective Tissue
 Prostate Antibodies  >9 publications with MT3 and Prostate
 Ovary Antibodies  >8 publications with MT3 and Ovary
 Spinal Cord Antibodies  >4 publications with MT3 and Spinal Cord
 Testis Antibodies  >1 publications with MT3 and Testis
 Adrenal Gland Antibodies  >1 publications with MT3 and Adrenal Gland
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