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Glutathione S Transferase Omega 1 (GSTomega1) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS763516

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. anti-Human GSTomega1 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Human GSTomega1 antibody was used as detection antibodies.… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Glutathione S Transferase Omega 1 (GSTomega1), ELISA Kit
Full Product Name
Human Glutathione S Transferase Omega 1 ELISA Kit
Product Gene Name
GSTomega1 elisa kit
Product Synonym Gene Name
GSTw1
Product Synonym Names
GSTomega1/GSTO1/Glutathione S-transferase omega-1/GSTO-1/S- (Phenacyl)glutathione reductase/SPG-R/Monomethylarsonic acid reductase/MMA (V) reductase/Glutathione S-transferase omega 1-1/GSTO 1-1/Glutathione-dependent dehydroascorbate reductase/GSTTLP28/P28 ; Glutathione S Transferase Omega 1
Species Reactivity
Human
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
0.156-10ng/ml
Sensitivity
0.094ng/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
24,796 Da
OMIM
605482
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of GSTomega1 elisa kit

Human GSTomega1 ELISA Kit – Cat# MBS763516

Typical Standard Curve of GSTomega1 elisa kit

Human GSTomega1 ELISA Kit, Typical Standard Curve – Cat# MBS763516

Other Notes

Small volumes of GSTomega1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSTomega1 purchase

MBS763516 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Glutathione S Transferase Omega 1 (GSTomega1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GSTomega1. The ELISA analytical biochemical technique of the MBS763516 kit is based on GSTomega1 antibody-GSTomega1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GSTomega1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GSTomega1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for GSTomega1. It may not necessarily be applicable to this product.

NCBI GI #
12652753
NCBI GeneID
9446
NCBI Accession #
AAH00127.1
UniProt Secondary Accession #
Q5TA03; Q7Z3T2; D3DRA3; F5H7H0
UniProt Related Accession #
P78417
NCBI Official Full Name
Glutathione S-transferase omega 1
NCBI Official Synonym Full Names
glutathione S-transferase omega 1
NCBI Official Symbol
GSTO1
NCBI Official Synonym Symbols
P28; SPG-R; GSTO 1-1; GSTTLp28; HEL-S-21
UniProt Protein Name
Glutathione S-transferase omega-1
UniProt Synonym Protein Names
Glutathione S-transferase omega 1-1; GSTO 1-1; Glutathione-dependent dehydroascorbate reductase (EC:1.8.5.1
Protein Family
Glutathione S-transferase
UniProt Gene Name
GSTO1
UniProt Synonym Gene Names
GSTTLP28; MMA(V) reductase; SPG-R
UniProt Entry Name
GSTO1_HUMAN
NCBI Protein Information
glutathione S-transferase omega-1

NCBI Summary for GSTomega1

The protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
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UniProt Comments for GSTomega1

GSTO1: Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family.

Protein type: EC 1.20.4.2; Xenobiotic Metabolism - drug metabolism - cytochrome P450; EC 2.5.1.18; Xenobiotic Metabolism - metabolism by cytochrome P450; Other Amino Acids Metabolism - glutathione; Transferase; EC 1.8.5.1

Chromosomal Location of Human Ortholog: 10q25.1

Cellular Component: axon; basement membrane; cytoplasm; cytosol; myelin sheath; nuclear membrane

Molecular Function: glutathione dehydrogenase (ascorbate) activity; glutathione transferase activity; methylarsonate reductase activity; oxidoreductase activity; protein binding

Biological Process: glutathione metabolic process; L-ascorbic acid biosynthetic process; L-ascorbic acid metabolic process; methylation; positive regulation of skeletal muscle contraction via regulation of the release of sequestered calcium ion; xenobiotic catabolic process; xenobiotic metabolic process
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Research Articles on GSTomega1

1. The present study provided epidemiological evidence for a significantly increased risk of UCB in ever smokers with the Ala/Ala genotype of the GSTO1 gene and the Arg/Arg genotype of the SULT1A1 gene.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GSTomega1 elisa kit

 Reference Product  PubMed Publications
 GSTP1 elisa kit  >31 publications with GSTomega1 and GSTP1
 GSTM1 elisa kit  >23 publications with GSTomega1 and GSTM1
 GSTT1 elisa kit  >20 publications with GSTomega1 and GSTT1
 GSTA1 elisa kit  >15 publications with GSTomega1 and GSTA1
 GSTM3 elisa kit  >11 publications with GSTomega1 and GSTM3
 GSTM2 elisa kit  >11 publications with GSTomega1 and GSTM2
 GSTA4 elisa kit  >7 publications with GSTomega1 and GSTA4
 GPX2 elisa kit  >2 publications with GSTomega1 and GPX2
 GSR elisa kit  >2 publications with GSTomega1 and GSR
 GSTT2B elisa kit  >1 publications with GSTomega1 and GSTT2B

Pathways associated with GSTomega1 elisa kit

 Products by Pathway  Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Glutathione Conjugation Pathway antibodies  Glutathione Conjugation Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Vitamins And Cofactors Pathway antibodies  Metabolism Of Vitamins And Cofactors Pathway Diagram

Diseases associated with GSTomega1 elisa kit

 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >25 publications with GSTomega1 and Brain Diseases
 Neurodegenerative Diseases Antibodies  >20 publications with GSTomega1 and Neurodegenerative Diseases
 Inflammation Antibodies  >11 publications with GSTomega1 and Inflammation
 Cardiovascular Diseases Antibodies  >10 publications with GSTomega1 and Cardiovascular Diseases
 Skin Diseases Antibodies  >10 publications with GSTomega1 and Skin Diseases
 Poisoning Antibodies  >8 publications with GSTomega1 and Poisoning
 Neurotoxicity Syndromes Antibodies  >7 publications with GSTomega1 and Neurotoxicity Syndromes
 Lung Diseases Antibodies  >7 publications with GSTomega1 and Lung Diseases
 Leukemia Antibodies  >6 publications with GSTomega1 and Leukemia
 Liver Diseases Antibodies  >6 publications with GSTomega1 and Liver Diseases

Organs/Tissues associated with GSTomega1 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >26 publications with GSTomega1 and Liver
 Blood Antibodies  >23 publications with GSTomega1 and Blood
 Brain Antibodies  >13 publications with GSTomega1 and Brain
 Bladder Antibodies  >8 publications with GSTomega1 and Bladder
 Lung Antibodies  >7 publications with GSTomega1 and Lung
 Vascular Antibodies  >6 publications with GSTomega1 and Vascular
 Heart Antibodies  >6 publications with GSTomega1 and Heart
 Muscle Antibodies  >5 publications with GSTomega1 and Muscle
 Kidney Antibodies  >5 publications with GSTomega1 and Kidney
 Prostate Antibodies  >5 publications with GSTomega1 and Prostate
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