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Insulin-Like Growth Factor-Binding Protein 5 (IGFBP-5) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS763578

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti-Human IGFBP-5 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Human IGFBP-5 antibody was used as detection antibodies. The… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Insulin-like growth factor-binding protein 5 (IGFBP-5), ELISA Kit
Full Product Name
Human Insulin-like growth factor-binding protein 5 ELISA Kit
Product Gene Name
IGFBP-5 elisa kit
Product Synonym Names
IGFBP-5/IBP5/IBP-5/IGF-binding protein 5/insulin-like growth factor binding protein 5/IGFBP5
Species Reactivity
Human
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
62.5-4000pg/ml
Sensitivity
37.5pg/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
30,570 Da
OMIM
146734
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of IGFBP-5 elisa kit

Human IGFBP-5 ELISA Kit – Cat# MBS763578

Typical Standard Curve of IGFBP-5 elisa kit

Human IGFBP-5 ELISA Kit, Typical Standard Curve – Cat# MBS763578

Other Notes

Small volumes of IGFBP-5 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IGFBP-5 purchase

MBS763578 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Insulin-like growth factor-binding protein 5 (IGFBP-5) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IGFBP-5. The ELISA analytical biochemical technique of the MBS763578 kit is based on IGFBP-5 antibody-IGFBP-5 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IGFBP-5 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IGFBP-5. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for IGFBP-5. It may not necessarily be applicable to this product.

NCBI GI #
10834982
NCBI GeneID
3488
NCBI Accession #
NP_000590.1
UniProt Secondary Accession #
Q5U0A3
UniProt Related Accession #
P24593
GenBank Nucleotide #
NM_000599.3
NCBI Official Full Name
insulin-like growth factor-binding protein 5
NCBI Official Synonym Full Names
insulin like growth factor binding protein 5
NCBI Official Symbol
IGFBP5
NCBI Official Synonym Symbols
IBP5
UniProt Protein Name
Insulin-like growth factor-binding protein 5
Protein Family
Insulin-like growth factor-binding protein
UniProt Gene Name
IGFBP5
UniProt Synonym Gene Names
IBP5; IBP-5; IGF-binding protein 5; IGFBP-5
UniProt Entry Name
IBP5_HUMAN
NCBI Protein Information
insulin-like growth factor-binding protein 5

UniProt Comments for IGFBP-5

IGFBP5: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

Protein type: Cell cycle regulation; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: extracellular region; insulin-like growth factor binding protein complex

Molecular Function: fibronectin binding; insulin-like growth factor I binding; insulin-like growth factor II binding; protein binding

Biological Process: cellular protein metabolic process; negative regulation of cell migration; negative regulation of insulin-like growth factor receptor signaling pathway; negative regulation of smooth muscle cell migration; negative regulation of smooth muscle cell proliferation; negative regulation of translation
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Research Articles on IGFBP-5

1. Data indicate co-localization of insulin-like growth factor binding proteins IGFBP-4, IGFBP-5 in the syncytiotrophoblast layer of first trimester placental villi as early as 5 weeks of gestational age.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IGFBP-5 elisa kit

 Reference Product  PubMed Publications
 IGF1 elisa kit  >34 publications with IGFBP-5 and IGF1
 IGF2 elisa kit  >22 publications with IGFBP-5 and IGF2
 PTH elisa kit  >20 publications with IGFBP-5 and PTH
 PAPPA2 elisa kit  >10 publications with IGFBP-5 and PAPPA2
 THBS1 elisa kit  >4 publications with IGFBP-5 and THBS1
 FHL2 elisa kit  >4 publications with IGFBP-5 and FHL2
 SERPINE1 elisa kit  >1 publications with IGFBP-5 and SERPINE1

Pathways associated with IGFBP-5 elisa kit

 Products by Pathway  Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway antibodies  Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway Diagram
 Senescence And Autophagy Pathway antibodies  Senescence And Autophagy Pathway Diagram

Diseases associated with IGFBP-5 elisa kit

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >53 publications with IGFBP-5 and Carcinoma
 Breast Neoplasms Antibodies  >53 publications with IGFBP-5 and Breast Neoplasms
 Nervous System Diseases Antibodies  >39 publications with IGFBP-5 and Nervous System Diseases
 Inflammation Antibodies  >24 publications with IGFBP-5 and Inflammation
 Brain Diseases Antibodies  >23 publications with IGFBP-5 and Brain Diseases
 Necrosis Antibodies  >23 publications with IGFBP-5 and Necrosis
 Cardiovascular Diseases Antibodies  >23 publications with IGFBP-5 and Cardiovascular Diseases
 Hypertrophy Antibodies  >22 publications with IGFBP-5 and Hypertrophy
 Fibrosis Antibodies  >19 publications with IGFBP-5 and Fibrosis
 Neoplasms, Experimental Antibodies  >18 publications with IGFBP-5 and Neoplasms, Experimental

Organs/Tissues associated with IGFBP-5 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >154 publications with IGFBP-5 and Muscle
 Bone Antibodies  >133 publications with IGFBP-5 and Bone
 Ovary Antibodies  >70 publications with IGFBP-5 and Ovary
 Vascular Antibodies  >56 publications with IGFBP-5 and Vascular
 Liver Antibodies  >55 publications with IGFBP-5 and Liver
 Connective Tissue Antibodies  >55 publications with IGFBP-5 and Connective Tissue
 Brain Antibodies  >55 publications with IGFBP-5 and Brain
 Mammary Gland Antibodies  >47 publications with IGFBP-5 and Mammary Gland
 Kidney Antibodies  >43 publications with IGFBP-5 and Kidney
 Embryonic Tissue Antibodies  >41 publications with IGFBP-5 and Embryonic Tissue
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