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Protein Tyrosine Phosphatase, Non-Receptor Type 14 (PTPN14) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS763738

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti-Human PTPN14 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Human PTPN14 antibody was used as detection antibodies. The… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
protein tyrosine phosphatase, non-receptor type 14 (PTPN14), ELISA Kit
Full Product Name
Human protein tyrosine phosphatase, non-receptor type 14 ELISA Kit
Product Gene Name
PTPN14 elisa kit
Species Reactivity
Human
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
78.125-5000pg/ml
Sensitivity
46.875pg/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
135,261 Da
OMIM
603155
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of PTPN14 elisa kit

Human PTPN14 ELISA Kit – Cat# MBS763738

Typical Standard Curve of PTPN14 elisa kit

Human PTPN14 ELISA Kit, Typical Standard Curve – Cat# MBS763738

Other Notes

Small volumes of PTPN14 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTPN14 purchase

MBS763738 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the protein tyrosine phosphatase, non-receptor type 14 (PTPN14) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PTPN14. The ELISA analytical biochemical technique of the MBS763738 kit is based on PTPN14 antibody-PTPN14 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PTPN14 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PTPN14. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for PTPN14. It may not necessarily be applicable to this product.

NCBI GI #
85396880
NCBI GeneID
5784
NCBI Accession #
AAI04804.1
UniProt Secondary Accession #
Q5VSI0
UniProt Related Accession #
Q15678
NCBI Official Full Name
Protein tyrosine phosphatase, non-receptor type 14
NCBI Official Synonym Full Names
protein tyrosine phosphatase, non-receptor type 14
NCBI Official Symbol
PTPN14
NCBI Official Synonym Symbols
PEZ; PTP36
UniProt Protein Name
Tyrosine-protein phosphatase non-receptor type 14
UniProt Synonym Protein Names
Protein-tyrosine phosphatase pez
Protein Family
Tyrosine-protein phosphatase non-receptor
UniProt Gene Name
PTPN14
UniProt Synonym Gene Names
PEZ; PTPD2
UniProt Entry Name
PTN14_HUMAN
NCBI Protein Information
tyrosine-protein phosphatase non-receptor type 14

NCBI Summary for PTPN14

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia. [provided by RefSeq, Sep 2010]
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UniProt Comments for PTPN14

PTPN14: a non-receptor phospho-tyrosine protein phosphatase. Reported to be mutated in a small percentage of human cancers including colorectal cancers and a smaller fraction of lung, breast, and gastric cancers. May play a role in liver metastases and tumour invasion in pancreatic cancer. Contains 1 FERM domain.

Protein type: EC 3.1.3.48; Motility/polarity/chemotaxis; Protein phosphatase, tyrosine (non-receptor)

Chromosomal Location of Human Ortholog: 1q32.2

Cellular Component: cytoplasm; cytoskeleton; nucleoplasm; nucleus

Molecular Function: protein binding; protein tyrosine phosphatase activity; receptor tyrosine kinase binding; transcription cofactor activity

Biological Process: lymphangiogenesis; negative regulation of cell proliferation; protein amino acid dephosphorylation; regulation of protein export from nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent

Disease: Choanal Atresia And Lymphedema
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Research Articles on PTPN14

1. Findings indicate a pathway involving protein-tyrosine phosphatase D2 PTPD2 (PTPN14) and the lipid second messenger phosphatidic acid that promotes ERBB2 receptor function.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PTPN14 elisa kit

 Reference Product  PubMed Publications
 YAP1 elisa kit  >4 publications with PTPN14 and YAP1
 TGFB1 elisa kit  >2 publications with PTPN14 and TGFB1
 FLT4 elisa kit  >2 publications with PTPN14 and FLT4
 CTNNB1 elisa kit  >1 publications with PTPN14 and CTNNB1
 WWC1 elisa kit  >1 publications with PTPN14 and WWC1

Diseases associated with PTPN14 elisa kit

 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >4 publications with PTPN14 and Lung Neoplasms
 Cell Transformation, Neoplastic Antibodies  >3 publications with PTPN14 and Cell Transformation, Neoplastic
 Lung Diseases Antibodies  >2 publications with PTPN14 and Lung Diseases
 Vascular Diseases Antibodies  >1 publications with PTPN14 and Vascular Diseases
 Neoplasms, Experimental Antibodies  >1 publications with PTPN14 and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >1 publications with PTPN14 and Liver Neoplasms
 Disease Models, Animal Antibodies  >1 publications with PTPN14 and Disease Models, Animal
 Hyperplasia Antibodies  >1 publications with PTPN14 and Hyperplasia
 CHOANAL ATRESIA AND LYMPHEDEMA Antibodies  >1 publications with PTPN14 and CHOANAL ATRESIA AND LYMPHEDEMA
 Neoplasm Metastasis Antibodies  >1 publications with PTPN14 and Neoplasm Metastasis

Organs/Tissues associated with PTPN14 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >5 publications with PTPN14 and Lung
 Vascular Antibodies  >4 publications with PTPN14 and Vascular
 Blood Antibodies  >2 publications with PTPN14 and Blood
 Muscle Antibodies  >1 publications with PTPN14 and Muscle
 Placenta Antibodies  >1 publications with PTPN14 and Placenta
 Heart Antibodies  >1 publications with PTPN14 and Heart
 Mammary Gland Antibodies  >1 publications with PTPN14 and Mammary Gland
 Brain Antibodies  >1 publications with PTPN14 and Brain
 Liver Antibodies  >1 publications with PTPN14 and Liver
 Kidney Antibodies  >1 publications with PTPN14 and Kidney
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