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Mu-Type Opioid Receptor (OPRM1) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS764255

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti-Human OPRM1antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Human OPRM1 antibody was used as detection antibodies. The… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Mu-type opioid receptor (OPRM1), ELISA Kit
Full Product Name
Human Mu-type opioid receptor ELISA Kit
Product Gene Name
OPRM1 elisa kit
Product Synonym Names
OPRM1 (Mu-type opioid receptor)/LMOR/MOP/MOR/MOR1/hMOP/M-OR-1/MOR-1/Mu opiate receptor/opioid receptor; mu 1/OPRM
Species Reactivity
Human
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
0.156-10ng/ml
Sensitivity
0.094ng/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
43,317 Da
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of OPRM1 elisa kit

Human OPRM1 ELISA Kit – Cat# MBS764255

Typical Standard Curve of OPRM1 elisa kit

Human OPRM1 ELISA Kit, Typical Standard Curve – Cat# MBS764255

Other Notes

Small volumes of OPRM1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OPRM1 purchase

MBS764255 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Mu-type opioid receptor (OPRM1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing OPRM1. The ELISA analytical biochemical technique of the MBS764255 kit is based on OPRM1 antibody-OPRM1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect OPRM1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, OPRM1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for OPRM1. It may not necessarily be applicable to this product.

NCBI GI #
145553980
NCBI GeneID
25601
NCBI Accession #
NP_001033688.2
UniProt Secondary Accession #
Q2TV20; Q2TV21; Q4VWM5; Q4VWM7; Q4VWX7; Q4VWX8; Q62846; Q64064; Q64120
UniProt Related Accession #
P33535
GenBank Nucleotide #
NM_001038599.2
NCBI Official Full Name
mu-type opioid receptor isoform 1B2
NCBI Official Synonym Full Names
opioid receptor, mu 1
NCBI Official Symbol
Oprm1
NCBI Official Synonym Symbols
MORA; Oprm; Oprrm1
UniProt Protein Name
Mu-type opioid receptor
UniProt Synonym Protein Names
Opioid receptor B
Protein Family
Mu-type opioid receptor
UniProt Gene Name
Oprm1
UniProt Synonym Gene Names
Ror-b; M-OR-1; MOR-1
UniProt Entry Name
OPRM_RAT
NCBI Protein Information
mu-type opioid receptor

NCBI Summary for OPRM1

receptor that binds morphine with high affinity [RGD, Feb 2006]

UniProt Comments for OPRM1

MOR-1: a Gi-protein-coupled receptor for beta-endorphin, morphine and other opiates. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Ligand-binding inactivates adenylyl cyclase, and activates a variety of G-beta-gamma-dependent pathways including the MAPK and the PI3K/Akt cascades. Two splice-variant isoforms have been described.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral

Cellular Component: cytoplasm; cytosol; dendrite; dendrite cytoplasm; focal adhesion; integral to membrane; integral to plasma membrane; lipid raft; membrane; perikaryon; sarcolemma

Molecular Function: beta-endorphin receptor activity; filamin binding; G-protein alpha-subunit binding; G-protein beta-subunit binding; G-protein coupled receptor activity; neuropeptide binding; opioid receptor activity; protein binding; protein C-terminus binding; protein domain specific binding; voltage-gated calcium channel activity

Biological Process: acute inflammatory response to antigenic stimulus; behavioral response to ethanol; dopamine receptor, adenylate cyclase activating pathway; eating behavior; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); immune response; locomotory behavior; negative regulation of adenylate cyclase activity; negative regulation of cAMP biosynthetic process; negative regulation of nitric oxide biosynthetic process; neuropeptide signaling pathway; opioid receptor, adenylate cyclase inhibiting pathway; positive regulation of appetite; positive regulation of neurogenesis; positive regulation of nitric oxide biosynthetic process; reduction of cytosolic calcium ion concentration; regulation of excitatory postsynaptic membrane potential; regulation of sensory perception of pain; response to cocaine; response to ethanol; response to food; response to lipopolysaccharide; response to morphine; response to radiation; sensory perception of pain; wound healing
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Research Articles on OPRM1

1. Activation of the mu opioid receptor (MOR) causes GTP to bind to and to activate Go (alphaobetagamma)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with OPRM1 elisa kit

 Reference Product  PubMed Publications
 Oprd1 elisa kit  >40 publications with OPRM1 and Oprd1
 Drd2 elisa kit  >38 publications with OPRM1 and Drd2
 Drd4 elisa kit  >20 publications with OPRM1 and Drd4
 Pomc elisa kit  >16 publications with OPRM1 and Pomc
 Arrb2 elisa kit  >14 publications with OPRM1 and Arrb2
 Pdyn elisa kit  >8 publications with OPRM1 and Pdyn
 Cnr2 elisa kit  >1 publications with OPRM1 and Cnr2

Pathways associated with OPRM1 elisa kit

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 G-protein Activation Pathway antibodies  G-protein Activation Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Morphine Addiction Pathway antibodies  Morphine Addiction Pathway Diagram
 Morphine Addiction Pathway antibodies  Morphine Addiction Pathway Diagram

Diseases associated with OPRM1 elisa kit

 Disease Name  Pubmed Publications
 Pain Antibodies  >202 publications with OPRM1 and Pain
 Substance-Related Disorders Antibodies  >191 publications with OPRM1 and Substance-Related Disorders
 Nervous System Diseases Antibodies  >145 publications with OPRM1 and Nervous System Diseases
 Alcoholism Antibodies  >98 publications with OPRM1 and Alcoholism
 Pain, Postoperative Antibodies  >52 publications with OPRM1 and Pain, Postoperative
 Heroin Dependence Antibodies  >35 publications with OPRM1 and Heroin Dependence
 Nausea Antibodies  >26 publications with OPRM1 and Nausea
 Vomiting Antibodies  >23 publications with OPRM1 and Vomiting
 Cocaine-Related Disorders Antibodies  >19 publications with OPRM1 and Cocaine-Related Disorders
 Morphine Dependence Antibodies  >17 publications with OPRM1 and Morphine Dependence

Organs/Tissues associated with OPRM1 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >13 publications with OPRM1 and Mixed
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