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ATP-Binding Cassette Sub-Family G Member 3 (AbCG3) ELISA Kit for Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS764266

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti-Mouse AbCG3 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Mouse AbCG3 antibody was used as detection antibodies. The… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ATP-binding cassette sub-family G member 3 (AbCG3), ELISA Kit
Full Product Name
Mouse ATP-binding cassette sub-family G member 3 ELISA Kit
Product Gene Name
AbCG3 elisa kit
Product Synonym Names
AbCG3
Species Reactivity
Mouse
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
0.313-20ng/ml
Sensitivity
0.188ng/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
86,628 Da
OMIM
603076
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of AbCG3 elisa kit

Mouse AbCG3 ELISA Kit – Cat# MBS764266

Typical Standard Curve of AbCG3 elisa kit

Mouse AbCG3 ELISA Kit, Typical Standard Curve – Cat# MBS764266

Other Notes

Small volumes of AbCG3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AbCG3 purchase

MBS764266 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ATP-binding cassette sub-family G member 3 (AbCG3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing AbCG3. The ELISA analytical biochemical technique of the MBS764266 kit is based on AbCG3 antibody-AbCG3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AbCG3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AbCG3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for AbCG3. It may not necessarily be applicable to this product.

NCBI GI #
46592956
NCBI GeneID
9619
NCBI Accession #
NP_997057.1
UniProt Secondary Accession #
Q86SU8; Q96L76; Q9BXK6; Q9BXK7; Q9BXK8; Q9BXK9; Q9BXL0; Q9BXL1; Q9BXL2; Q9BXL3; Q9BXL4
UniProt Related Accession #
P45844
GenBank Nucleotide #
NM_207174.1
NCBI Official Full Name
ATP-binding cassette sub-family G member 1 isoform 3
NCBI Official Synonym Full Names
ATP binding cassette subfamily G member 1
NCBI Official Symbol
ABCG1
NCBI Official Synonym Symbols
ABC8; WHITE1
UniProt Protein Name
ATP-binding cassette sub-family G member 1
UniProt Synonym Protein Names
ATP-binding cassette transporter 8; White protein homolog
Protein Family
ABC transporter G family
UniProt Gene Name
ABCG1
UniProt Synonym Gene Names
ABC8; WHT1
UniProt Entry Name
ABCG1_HUMAN
NCBI Protein Information
ATP-binding cassette sub-family G member 1

NCBI Summary for AbCG3

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq, Jul 2008]
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UniProt Comments for AbCG3

ABCG1: Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ABC family

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: endosome; external side of plasma membrane; Golgi apparatus; integral to membrane; integral to plasma membrane; intracellular membrane-bound organelle; mitochondrion; nucleoplasm; plasma membrane; recycling endosome

Molecular Function: ADP binding; ATP binding; cholesterol binding; cholesterol transporter activity; phospholipid binding; phospholipid transporter activity; protein heterodimerization activity; protein homodimerization activity; sterol-transporting ATPase activity; toxin transporter activity

Biological Process: amyloid precursor protein catabolic process; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; intracellular cholesterol transport; lipoprotein metabolic process; phospholipid efflux; phospholipid homeostasis; positive regulation of cholesterol biosynthetic process; regulation of transcription, DNA-dependent; response to lipid; response to organic substance; reverse cholesterol transport; transmembrane transport
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Research Articles on AbCG3

1. Expression analysis revealed an association between ABCG1 methylation and lipid levels that might be partly mediated by ABCG1 expression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with AbCG3 elisa kit

 Reference Product  PubMed Publications
 SCARB1 elisa kit  >84 publications with AbCG3 and SCARB1
 ABCG4 elisa kit  >42 publications with AbCG3 and ABCG4
 APOA1 elisa kit  >38 publications with AbCG3 and APOA1
 NPC1 elisa kit  >13 publications with AbCG3 and NPC1
 NR1H3 elisa kit  >7 publications with AbCG3 and NR1H3
 NR1H2 elisa kit  >4 publications with AbCG3 and NR1H2
 RARS elisa kit  >2 publications with AbCG3 and RARS
 COL4A3BP elisa kit  >1 publications with AbCG3 and COL4A3BP

Pathways associated with AbCG3 elisa kit

 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters In Lipid Homeostasis Pathway antibodies  ABC Transporters In Lipid Homeostasis Pathway Diagram
 ABC-family Proteins Mediated Transport Pathway antibodies  ABC-family Proteins Mediated Transport Pathway Diagram
 HDL-mediated Lipid Transport Pathway antibodies  HDL-mediated Lipid Transport Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Lipoprotein Metabolism Pathway antibodies  Lipoprotein Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Nuclear Receptors In Lipid Metabolism And Toxicity Pathway antibodies  Nuclear Receptors In Lipid Metabolism And Toxicity Pathway Diagram

Diseases associated with AbCG3 elisa kit

 Disease Name  Pubmed Publications
 Atherosclerosis Antibodies  >340 publications with AbCG3 and Atherosclerosis
 Cardiovascular Diseases Antibodies  >234 publications with AbCG3 and Cardiovascular Diseases
 Inflammation Antibodies  >114 publications with AbCG3 and Inflammation
 Dyslipidemias Antibodies  >62 publications with AbCG3 and Dyslipidemias
 Liver Diseases Antibodies  >58 publications with AbCG3 and Liver Diseases
 Fatty Liver Antibodies  >48 publications with AbCG3 and Fatty Liver
 Hyperlipidemias Antibodies  >40 publications with AbCG3 and Hyperlipidemias
 Nervous System Diseases Antibodies  >39 publications with AbCG3 and Nervous System Diseases
 Heart Diseases Antibodies  >36 publications with AbCG3 and Heart Diseases
 Hypercholesterolemia Antibodies  >34 publications with AbCG3 and Hypercholesterolemia

Organs/Tissues associated with AbCG3 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >346 publications with AbCG3 and Liver
 Blood Antibodies  >242 publications with AbCG3 and Blood
 Brain Antibodies  >62 publications with AbCG3 and Brain
 Lung Antibodies  >45 publications with AbCG3 and Lung
 Muscle Antibodies  >38 publications with AbCG3 and Muscle
 Kidney Antibodies  >27 publications with AbCG3 and Kidney
 Intestine Antibodies  >23 publications with AbCG3 and Intestine
 Connective Tissue Antibodies  >13 publications with AbCG3 and Connective Tissue
 Pancreas Antibodies  >12 publications with AbCG3 and Pancreas
 Spleen Antibodies  >12 publications with AbCG3 and Spleen
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