Protein S100-A7 (S100A7) ELISA Kit for Human

Name: Human S100A7 ELISA Kit; Protein S100-A7; MyBioSource
Brand: MyBioSource
SKU: MBS764372
Price: 405 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS764372

Principle of the Assay: This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti-S100A7 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-S100A7 antibody was used as detection antibodies. The standards, test… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Protein S100-A7 (S100A7), ELISA Kit

Full Product Name

Human Protein S100-A7 ELISA Kit

Product Gene Name

S100A7 elisa kit

Product Synonym Names

S100A7/S100 Calcium Binding Protein A7/Protein S100-A7/Psoriasin/PSOR1/S100A7C/HID 5/HID5/HID-5/psoriasin 1

Species Reactivity

Human

Assay Type

Sandwich ELISA, Double Antibody

Samples

Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples

Detection Range

0.156-10ng/ml

Sensitivity

0.094ng/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of S100A7. No significant cross-reactivity or interference between S100A7 and analogues was observed.

Preparation and Storage

Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C

Inter-assay Precision

Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level S100A7 were tested on 3 different plates, 8 replicates in each plate. CV (%) = SD/meanX100. Inter-Assay: CV<10%

Intra-assay Precision

Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level S100A7 were tested 20 times on one plate, respectively. Intra-Assay: CV<8%

Molecular Weight

11,471 Da

OMIM

600353

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of S100A7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for S100A7 purchase

MBS764372 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Protein S100-A7 (S100A7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing S100A7. The ELISA analytical biochemical technique of the MBS764372 kit is based on S100A7 antibody-S100A7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect S100A7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, S100A7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for S100A7. It may not necessarily be applicable to this product.

NCBI GI #

115298657

NCBI GeneID

6278

NCBI Accession #

NP_002954.2

UniProt Secondary Accession #

Q5SY67; Q6FGE3; Q9H1E2

UniProt Related Accession #

P31151

GenBank Nucleotide #

NM_002963.3

NCBI Official Full Name

protein S100-A7

NCBI Official Synonym Full Names

S100 calcium binding protein A7

NCBI Official Symbol

S100A7

NCBI Official Synonym Symbols

PSOR1; S100A7c

UniProt Protein Name

Protein S100-A7

UniProt Synonym Protein Names

Psoriasin; S100 calcium-binding protein A7

Protein Family

Protein

UniProt Gene Name

S100A7

UniProt Synonym Gene Names

PSOR1; S100A7C

UniProt Entry Name

S10A7_HUMAN

NCBI Protein Information

protein S100-A7

NCBI Summary for S100A7

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities. [provided by RefSeq, Nov 2014]

UniProt Comments for S100A7

S100A7: is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known. [provided by RefSeq, Jul 2008]

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: cytoplasm; cytosol; endoplasmic reticulum; extracellular region; focal adhesion; nucleus

Molecular Function: calcium ion binding; protein binding; RAGE receptor binding; zinc ion binding

Biological Process: angiogenesis; defense response to Gram-negative bacterium; epidermis development; innate immune response; keratinocyte differentiation; response to lipopolysaccharide; response to reactive oxygen species; sequestering of metal ion

Research Articles on S100A7

1. The distinct modulations of the NF-kappaB - miR-29b - p53 pathway make S100A7 an oncogene.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with S100A7 elisa kit

Reference Product	PubMed Publications
RNASE7 elisa kit	>23 publications with S100A7 and RNASE7
S100A12 elisa kit	>14 publications with S100A7 and S100A12
COPS5 elisa kit	>6 publications with S100A7 and COPS5
FABP5 elisa kit	>5 publications with S100A7 and FABP5
MYC elisa kit	>2 publications with S100A7 and MYC
BRCA1 elisa kit	>1 publications with S100A7 and BRCA1

Pathways associated with S100A7 elisa kit

Products by Pathway	Pathway Diagram
Validated Targets Of C-MYC Transcriptional Repression Pathway antibodies	Validated Targets Of C-MYC Transcriptional Repression Pathway Diagram

Diseases associated with S100A7 elisa kit

Disease Name	Pubmed Publications
Psoriasis Antibodies	>88 publications with S100A7 and Psoriasis
Inflammation Antibodies	>66 publications with S100A7 and Inflammation
Breast Neoplasms Antibodies	>43 publications with S100A7 and Breast Neoplasms
Dermatitis Antibodies	>15 publications with S100A7 and Dermatitis
Necrosis Antibodies	>15 publications with S100A7 and Necrosis
Lung Diseases Antibodies	>12 publications with S100A7 and Lung Diseases
Congenital, Hereditary, and Neonatal Diseases and Abnormalities Antibodies	>12 publications with S100A7 and Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Lung Neoplasms Antibodies	>11 publications with S100A7 and Lung Neoplasms
Cell Transformation, Neoplastic Antibodies	>9 publications with S100A7 and Cell Transformation, Neoplastic
Neoplasms, Experimental Antibodies	>9 publications with S100A7 and Neoplasms, Experimental

Organs/Tissues associated with S100A7 elisa kit

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>166 publications with S100A7 and Skin
Mouth Antibodies	>19 publications with S100A7 and Mouth
Brain Antibodies	>8 publications with S100A7 and Brain
Eye Antibodies	>7 publications with S100A7 and Eye
Prostate Antibodies	>4 publications with S100A7 and Prostate
Muscle Antibodies	>2 publications with S100A7 and Muscle
Larynx Antibodies	>2 publications with S100A7 and Larynx
Uterus Antibodies	>1 publications with S100A7 and Uterus
Pharynx Antibodies	>1 publications with S100A7 and Pharynx