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Inositol Monophosphatase 2 (IMPA2) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS764575

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti-Human IMPA2 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Human IMPA2 antibody was used as detection antibodies. The… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Inositol monophosphatase 2 (IMPA2), ELISA Kit
Full Product Name
Human Inositol monophosphatase 2 ELISA Kit
Product Gene Name
IMPA2 elisa kit
Product Synonym Names
IMPA2 (Inositol monophosphatase 2)/IMP 2/IMPase 2/Inositol-1 (or 4)-monophosphatase 2/Myo-inositol monophosphatase A2
Species Reactivity
Human
Assay Type
Sandwich ELISA, Double Antibody
Samples
cell or tissue lysate, Other liquid samples
Detection Range
62.5-4000pg/ml
Sensitivity
37.5pg/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
28,512 Da
OMIM
605922
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of IMPA2 elisa kit

Human IMPA2 ELISA Kit – Cat# MBS764575

Typical Standard Curve of IMPA2 elisa kit

Human IMPA2 ELISA Kit, Typical Standard Curve – Cat# MBS764575

Other Notes

Small volumes of IMPA2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IMPA2 purchase

MBS764575 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Inositol monophosphatase 2 (IMPA2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IMPA2. The ELISA analytical biochemical technique of the MBS764575 kit is based on IMPA2 antibody-IMPA2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IMPA2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IMPA2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for IMPA2. It may not necessarily be applicable to this product.

NCBI GI #
7657236
NCBI GeneID
3613
NCBI Accession #
NP_055029.1
UniProt Secondary Accession #
Q9UJT3; B0YJ29
UniProt Related Accession #
O14732
GenBank Nucleotide #
NM_014214.2
NCBI Official Full Name
inositol monophosphatase 2
NCBI Official Synonym Full Names
inositol(myo)-1(or 4)-monophosphatase 2
NCBI Official Symbol
IMPA2
UniProt Protein Name
Inositol monophosphatase 2
UniProt Synonym Protein Names
Inositol-1(or 4)-monophosphatase 2; Myo-inositol monophosphatase A2
Protein Family
Inositol monophosphatase
UniProt Gene Name
IMPA2
UniProt Synonym Gene Names
IMP.18P; IMP 2; IMPase 2
UniProt Entry Name
IMPA2_HUMAN
NCBI Protein Information
inositol monophosphatase 2

NCBI Summary for IMPA2

This locus encodes an inositol monophosphatase. The encoded protein catalyzes the dephosphoylration of inositol monophosphate and plays an important role in phosphatidylinositol signaling. This locus may be associated with susceptibility to bipolar disorder. [provided by RefSeq, Jan 2011]

UniProt Comments for IMPA2

IMPA2: Can use myo-inositol monophosphates, scylloinositol 1,4- diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'- AMP as substrates. Has been implicated as the pharmacological target for lithium Li(+) action in brain. Belongs to the inositol monophosphatase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Carbohydrate Metabolism - inositol phosphate; Phosphatase (non-protein); EC 3.1.3.25; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 18p11.2

Cellular Component: cytoplasm; cytosol

Molecular Function: inositol-1(or 4)-monophosphatase activity; magnesium ion binding; protein binding; protein homodimerization activity

Biological Process: inositol biosynthetic process; inositol metabolic process; inositol phosphate dephosphorylation; inositol phosphate metabolic process; phosphate metabolic process; phosphoinositide phosphorylation; signal transduction
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Research Articles on IMPA2

1. results suggest that genetic variability at rs669838-IMPA2,rs4853694-INPP1, rs1732170-GSK3b and rs11921360-GSK3b genes is associated with a higher risk of attempting suicide in bipolar patients.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IMPA2 elisa kit

 Reference Product  PubMed Publications
 IMPA1 elisa kit  >13 publications with IMPA2 and IMPA1
 INPP1 elisa kit  >2 publications with IMPA2 and INPP1
 PLCB1 elisa kit  >1 publications with IMPA2 and PLCB1
 PLCD1 elisa kit  >1 publications with IMPA2 and PLCD1
 ISYNA1 elisa kit  >1 publications with IMPA2 and ISYNA1

Pathways associated with IMPA2 elisa kit

 Products by Pathway  Pathway Diagram
 D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway antibodies  D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway Diagram
 D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway antibodies  D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => Myo-inositol Pathway antibodies  Inositol Phosphate Metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => Myo-inositol Pathway Diagram
 Inositol Phosphate Metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => Myo-inositol Pathway antibodies  Inositol Phosphate Metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => Myo-inositol Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Phosphatidylinositol Signaling System Pathway antibodies  Phosphatidylinositol Signaling System Pathway Diagram

Diseases associated with IMPA2 elisa kit

 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >6 publications with IMPA2 and Brain Diseases
 Seizures, Febrile Antibodies  >5 publications with IMPA2 and Seizures, Febrile
 Learning Disorders Antibodies  >1 publications with IMPA2 and Learning Disorders

Organs/Tissues associated with IMPA2 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >15 publications with IMPA2 and Brain
 Blood Antibodies  >5 publications with IMPA2 and Blood
 Kidney Antibodies  >3 publications with IMPA2 and Kidney
 Skin Antibodies  >1 publications with IMPA2 and Skin
 Intestine Antibodies  >1 publications with IMPA2 and Intestine
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