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Transmembrane Protein 126a (TMEM126A) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS764784

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. anti-Human TMEM126A antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Human TMEM126A antibody was used as detection antibodies. The… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Transmembrane protein 126A (TMEM126A), ELISA Kit
Full Product Name
Human Transmembrane protein 126A ELISA Kit
Product Gene Name
TMEM126A elisa kit
Product Synonym Names
TMEM126A
Species Reactivity
Human
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
0.156-10ng/ml
Sensitivity
0.094ng/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
13,844 Da
OMIM
612988
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of TMEM126A elisa kit

Human TMEM126A ELISA Kit – Cat# MBS764784

Typical Standard Curve of TMEM126A elisa kit

Human TMEM126A ELISA Kit, Typical Standard Curve – Cat# MBS764784

Other Notes

Small volumes of TMEM126A elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TMEM126A purchase

MBS764784 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Transmembrane protein 126A (TMEM126A) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TMEM126A. The ELISA analytical biochemical technique of the MBS764784 kit is based on TMEM126A antibody-TMEM126A antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TMEM126A antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TMEM126A. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for TMEM126A. It may not necessarily be applicable to this product.

NCBI GI #
119595508
NCBI GeneID
84233
NCBI Accession #
EAW75102.1
UniProt Secondary Accession #
B2R570; E9PI16
UniProt Related Accession #
Q9H061
NCBI Official Full Name
transmembrane protein 126A
NCBI Official Synonym Full Names
transmembrane protein 126A
NCBI Official Symbol
TMEM126A
NCBI Official Synonym Symbols
OPA7
UniProt Protein Name
Transmembrane protein 126A
Protein Family
Transmembrane protein
UniProt Gene Name
TMEM126A
UniProt Entry Name
T126A_HUMAN
NCBI Protein Information
transmembrane protein 126A

NCBI Summary for TMEM126A

The protein encoded by this gene is a mitochondrial membrane protein of unknown function. Defects in this gene are a cause of optic atrophy type 7 (OPA7). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

UniProt Comments for TMEM126A

TMEM126A: Defects in TMEM126A are the cause of optic atrophy type 7 (OPA7). A hereditary condition that features progressive visual loss in association with optic atrophy. Atrophy of the optic disk indicates a deficiency in the number of nerve fibers which arise in the retina and converge to form the optic disk, optic nerve, optic chiasm and optic tracts. OPA7 is an autosomal recessive juvenile-onset optic atrophy characterized by severe bilateral deficiency in visual acuity, optic disk pallor, and central scotoma. Belongs to the TMEM126 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q14.1

Cellular Component: integral to membrane; mitochondrial inner membrane; mitochondrion

Biological Process: optic nerve development

Disease: Optic Atrophy 7 With Or Without Auditory Neuropathy
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Research Articles on TMEM126A

1. TMEM126A is a mitochondrial located mRNA (MLR) that may be translated in the mitochondrial surface and the protein is subsequently imported to the inner membrane

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with TMEM126A elisa kit

 Products by Pathway  Pathway Diagram
 Validated Targets Of C-MYC Transcriptional Repression Pathway antibodies  Validated Targets Of C-MYC Transcriptional Repression Pathway Diagram

Diseases associated with TMEM126A elisa kit

 Disease Name  Pubmed Publications
 Atrophy Antibodies  >4 publications with TMEM126A and Atrophy
 Mitochondrial Diseases Antibodies  >2 publications with TMEM126A and Mitochondrial Diseases
 Neurodegenerative Diseases Antibodies  >2 publications with TMEM126A and Neurodegenerative Diseases
 Nerve Degeneration Antibodies  >1 publications with TMEM126A and Nerve Degeneration

Organs/Tissues associated with TMEM126A elisa kit

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >4 publications with TMEM126A and Eye
 Brain Antibodies  >1 publications with TMEM126A and Brain
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