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Growth Differentiation Factor 7 (GDF7) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS765299

Principle of the Assay: This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti-GDF3 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-GDF3 antibody was used as detection antibodies. The standards, test… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Growth Differentiation Factor 7 (GDF7), ELISA Kit
Full Product Name
Human Growth Differentiation Factor 7 ELISA Kit
Product Gene Name
GDF7 elisa kit
Product Synonym Names
GDF7/BMP-12/BMP12/GDF-7/growth differentiation factor 7/growth/differentiation factor 7
Species Reactivity
Human
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
62.5-4000pg/ml
Sensitivity
37.5pg/ml
Specificity
This assay has high sensitivity and excellent specificity for detection of GDF3. No significant cross-reactivity or interference between GDF3 and analogues was observed.
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Inter-assay Precision
Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level GDF3 were tested on 3 different plates, 8 replicates in each plate. CV (%) = SD/meanX100. Inter-Assay: CV<10%
Intra-assay Precision
Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level GDF3 were tested 20 times on one plate, respectively. Intra-Assay: CV<8%
Molecular Weight
46,950 Da
OMIM
604651
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data/Standard Curve (for reference only) of GDF7 elisa kit

Human GDF7 ELISA Kit – Cat# MBS765299

Other Notes

Small volumes of GDF7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GDF7 purchase

MBS765299 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Growth Differentiation Factor 7 (GDF7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GDF7. The ELISA analytical biochemical technique of the MBS765299 kit is based on GDF7 antibody-GDF7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GDF7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GDF7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for GDF7. It may not necessarily be applicable to this product.

NCBI GI #
40786371
NCBI GeneID
151449
NCBI Accession #
BAD07014.1
UniProt Related Accession #
Q7Z4P5
NCBI Official Full Name
growth differentiation factor 7
NCBI Official Synonym Full Names
growth differentiation factor 7
NCBI Official Symbol
GDF7
NCBI Official Synonym Symbols
BMP12
UniProt Protein Name
Growth/differentiation factor 7
Protein Family
Growth/differentiation factor
UniProt Gene Name
GDF7
UniProt Synonym Gene Names
GDF-7
UniProt Entry Name
GDF7_HUMAN
NCBI Protein Information
growth/differentiation factor 7

NCBI Summary for GDF7

This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord. [provided by RefSeq, Jul 2008]
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UniProt Comments for GDF7

GDF7: May play an active role in the motor area of the primate neocortex. Belongs to the TGF-beta family.

Protein type: Secreted; Cytokine; Cell development/differentiation; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 2p24.1

Cellular Component: extracellular space

Molecular Function: cytokine activity; growth factor activity; protein binding; protein homodimerization activity; transforming growth factor beta receptor binding

Biological Process: activin receptor signaling pathway; axon guidance; BMP signaling pathway; branching morphogenesis of a tube; cell development; cell fate commitment; epithelial cell differentiation; forebrain morphogenesis; gland morphogenesis; growth; midbrain development; positive regulation of neuron differentiation; positive regulation of transcription, DNA-dependent; regulation of apoptosis; regulation of MAPKKK cascade; reproductive structure development; roof plate formation; spinal cord association neuron differentiation
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Research Articles on GDF7

1. closest protein-coding genes were respectively GDF7 (rs3072), which encodes a ligand in the bone morphogenetic protein pathway, and TBX5 (rs2701108), which encodes a transcription factor that regulates esophageal and cardiac development

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GDF7 elisa kit

 Reference Product  PubMed Publications
 BMPR2 elisa kit  >5 publications with GDF7 and BMPR2
 SHH elisa kit  >4 publications with GDF7 and SHH
 BMP7 elisa kit  >4 publications with GDF7 and BMP7
 TNMD elisa kit  >2 publications with GDF7 and TNMD

Pathways associated with GDF7 elisa kit

 Products by Pathway  Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram

Diseases associated with GDF7 elisa kit

 Disease Name  Pubmed Publications
 Abnormalities, Multiple Antibodies  >1 publications with GDF7 and Abnormalities, Multiple
 Congenital Abnormalities Antibodies  >1 publications with GDF7 and Congenital Abnormalities
 Genital Diseases, Male Antibodies  >1 publications with GDF7 and Genital Diseases, Male
 Cell Transformation, Neoplastic Antibodies  >1 publications with GDF7 and Cell Transformation, Neoplastic
 Inflammation Antibodies  >1 publications with GDF7 and Inflammation
 Disease Models, Animal Antibodies  >1 publications with GDF7 and Disease Models, Animal
 Infertility, Male Antibodies  >1 publications with GDF7 and Infertility, Male

Organs/Tissues associated with GDF7 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >14 publications with GDF7 and Brain
 Testis Antibodies  >1 publications with GDF7 and Testis
 Kidney Antibodies  >1 publications with GDF7 and Kidney
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