Galectin-1 (LGALS1) ELISA Kit for Human

Name: Human LGALS1 ELISA Kit; Galectin-1; MyBioSource
Brand: MyBioSource
SKU: MBS765403
Price: 405 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS765403

Principle of the Assay: This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Capture antibody was pre-coated onto 96-well plates. And the biotin conjugated antibody was used as detection antibodies. The standards, test samples and… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Galectin-1 (LGALS1), ELISA Kit

Full Product Name

Human Galectin-1 ELISA Kit

Product Gene Name

LGALS1 elisa kit

Product Synonym Names

GAL1 (Galectin 1 )/LGALS1/BHL/Galaptin/GBP/L-14/14 kDa laminin-binding protein/Gal-1/galectin 1/galectin-1/GBP/HBL/HLBP14/HPL/Lactose-binding lectin 1

Species Reactivity

Human

Assay Type

Sandwich ELISA, Double Antibody

Samples

Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples

Detection Range

0.781-50ng/ml

Sensitivity

0.469ng/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of LGALS1. No significant cross-reactivity or interference between LGALS1 and analogues was observed.

Preparation and Storage

Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C

Inter-assay Precision

CV<10%

Intra-assay Precision

CV<8%

Molecular Weight

14,716 Da

OMIM

150570

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of LGALS1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LGALS1 purchase

MBS765403 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Galectin-1 (LGALS1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LGALS1. The ELISA analytical biochemical technique of the MBS765403 kit is based on LGALS1 antibody-LGALS1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LGALS1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LGALS1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for LGALS1. It may not necessarily be applicable to this product.

NCBI GI #

4504981

NCBI GeneID

3956

NCBI Accession #

NP_002296.1

UniProt Secondary Accession #

Q9UDK5; B2R5E8

UniProt Related Accession #

P09382

GenBank Nucleotide #

NM_002305.3

NCBI Official Full Name

galectin-1

NCBI Official Synonym Full Names

lectin, galactoside-binding, soluble, 1

NCBI Official Symbol

LGALS1

NCBI Official Synonym Symbols

GBP; GAL1

UniProt Protein Name

Galectin-1

UniProt Synonym Protein Names

14 kDa laminin-binding protein; HLBP14; 14 kDa lectin; Beta-galactoside-binding lectin L-14-I; Galaptin; HBL; HPL; Lactose-binding lectin 1; Lectin galactoside-binding soluble 1; Putative MAPK-activating protein PM12; S-Lac lectin 1

Protein Family

Galectin

UniProt Gene Name

LGALS1

UniProt Synonym Gene Names

Gal-1; HLBP14

UniProt Entry Name

LEG1_HUMAN

NCBI Protein Information

galectin-1

NCBI Summary for LGALS1

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation. [provided by RefSeq, Jul 2008]

UniProt Comments for LGALS1

Galectin-1: May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Homodimer. Binds LGALS3BP. Interacts with CD2, CD3, CD4, CD7, CD43 and CD45. Interacts with laminin (via poly-N- acetyllactosamine). Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion. Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells.

Protein type: Secreted; Extracellular matrix; Cell adhesion

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: cell surface; cytoplasm; extracellular matrix; extracellular space; intracellular; nucleus; proteinaceous extracellular matrix

Molecular Function: glycoprotein binding; lactose binding; laminin binding; protein binding; protein homodimerization activity; signal transducer activity

Biological Process: apoptosis; multicellular organismal response to stress; myoblast differentiation; plasma cell differentiation; positive regulation of erythrocyte aggregation; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of virion penetration into host cell; regulation of apoptosis; response to axon injury; response to drug; signal transduction; T cell costimulation

Research Articles on LGALS1

1. no difference in cord blood concentration correlated with restricted or increased fetal growth

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with LGALS1 elisa kit

Reference Product	PubMed Publications
CD7 elisa kit	>20 publications with LGALS1 and CD7
MYC elisa kit	>13 publications with LGALS1 and MYC
TRPV5 elisa kit	>5 publications with LGALS1 and TRPV5
GEMIN4 elisa kit	>4 publications with LGALS1 and GEMIN4
UBC elisa kit	>3 publications with LGALS1 and UBC
PTPRC elisa kit	>2 publications with LGALS1 and PTPRC
SUSD2 elisa kit	>1 publications with LGALS1 and SUSD2
TNC elisa kit	>1 publications with LGALS1 and TNC

Pathways associated with LGALS1 elisa kit

Products by Pathway	Pathway Diagram
Validated Targets Of C-MYC Transcriptional Repression Pathway antibodies	Validated Targets Of C-MYC Transcriptional Repression Pathway Diagram

Diseases associated with LGALS1 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>142 publications with LGALS1 and Inflammation
Neoplasm Metastasis Antibodies	>79 publications with LGALS1 and Neoplasm Metastasis
Disease Models, Animal Antibodies	>75 publications with LGALS1 and Disease Models, Animal
Neoplasms, Experimental Antibodies	>54 publications with LGALS1 and Neoplasms, Experimental
Breast Neoplasms Antibodies	>45 publications with LGALS1 and Breast Neoplasms
Cell Transformation, Neoplastic Antibodies	>36 publications with LGALS1 and Cell Transformation, Neoplastic
Lung Neoplasms Antibodies	>36 publications with LGALS1 and Lung Neoplasms
Necrosis Antibodies	>32 publications with LGALS1 and Necrosis
Liver Diseases Antibodies	>24 publications with LGALS1 and Liver Diseases
Kidney Diseases Antibodies	>24 publications with LGALS1 and Kidney Diseases

Organs/Tissues associated with LGALS1 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>393 publications with LGALS1 and Blood
Brain Antibodies	>102 publications with LGALS1 and Brain
Vascular Antibodies	>93 publications with LGALS1 and Vascular
Muscle Antibodies	>70 publications with LGALS1 and Muscle
Bone Antibodies	>62 publications with LGALS1 and Bone
Nerve Antibodies	>61 publications with LGALS1 and Nerve
Lung Antibodies	>58 publications with LGALS1 and Lung
Skin Antibodies	>58 publications with LGALS1 and Skin
Liver Antibodies	>54 publications with LGALS1 and Liver
Embryonic Tissue Antibodies	>53 publications with LGALS1 and Embryonic Tissue