Peptide Yy (PYY) ELISA Kit for Human

Name: Human PYY ELISA Kit; Peptide Yy; MyBioSource
Brand: MyBioSource
SKU: MBS765494
Price: 405 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS765494

Principle of the Assay: This kit was based on Competitive-ELISA detection method. The microtiter plate provided in this kit has been pre-coated with target. During the reaction, target in the sample or standard competes with a fixed amount of target on the… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Peptide YY (PYY), ELISA Kit

Full Product Name

Human Peptide YY ELISA Kit

Product Gene Name

PYY elisa kit

Product Synonym Names

PYY/Peptide YY/PYY-I/Peptide tyrosine tyrosine

Species Reactivity

Human

Assay Type

Competitive ELISA, Coated with Antigen

Samples

Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples

Detection Range

31.25-2000pg/ml

Sensitivity

18.75pg/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of PYY. No significant cross-reactivity or interference between PYY and analogues was observed.

Preparation and Storage

Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C

Inter-assay Precision

CV<10%

Intra-assay Precision

CV<8%

Molecular Weight

10,360 Da

OMIM

600781

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of PYY elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PYY purchase

MBS765494 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Peptide YY (PYY) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PYY. The ELISA analytical biochemical technique of the MBS765494 kit is based on PYY antibody-PYY antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PYY antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PYY. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for PYY. It may not necessarily be applicable to this product.

NCBI GI #

300068956

NCBI GeneID

5697

NCBI Accession #

NP_004151.3

UniProt Secondary Accession #

Q5U5Q6; Q6FGH8

UniProt Related Accession #

P10082

GenBank Nucleotide #

NM_004160.5

NCBI Official Full Name

peptide YY preproprotein

NCBI Official Synonym Full Names

peptide YY

NCBI Official Symbol

PYY

NCBI Official Synonym Symbols

PYY1; PYY-I

UniProt Protein Name

Peptide YY

UniProt Synonym Protein Names

PYY-II

Protein Family

Peptide

UniProt Gene Name

PYY

UniProt Synonym Gene Names

PYY

UniProt Entry Name

PYY_HUMAN

NCBI Protein Information

peptide YY

NCBI Summary for PYY

This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded preproprotein is proteolytically processed to generate two alternative peptide products that differ in length by three amino acids. These peptides, secreted by endocrine cells in the gut, exhibit different binding affinities for each of the neuropeptide Y receptors. Binding of the encoded peptides to these receptors mediates regulation of pancreatic secretion, gut mobility and energy homeostasis. Rare variations in this gene could increase susceptibility to obesity and elevated serum levels of the encoded peptides may be associated with anorexia nervosa. [provided by RefSeq, Feb 2016]

UniProt Comments for PYY

PYY: This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Belongs to the NPY family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 17q21.1

Cellular Component: extracellular region; extracellular space

Molecular Function: G-protein-coupled receptor binding; hormone activity; neuropeptide hormone activity; protein binding

Biological Process: cell motility; cell proliferation; cell-cell signaling; cytoskeleton organization and biogenesis; digestion; eating behavior; feeding behavior; G-protein coupled receptor protein signaling pathway; neuropeptide signaling pathway; regulation of appetite

Disease: Obesity

Research Articles on PYY

1. Data suggest plasma PYY (peptide YY) and GLP1 (glucagon-like peptide 1) can be regulated by digestion-resistant diet factors; intake of soluble dietary fiber (prebiotic Fibersol-2) in a tea with meal up-regulated plasma PYY/GLP1 and decreased hunger.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PYY elisa kit

Reference Product	PubMed Publications
CCK elisa kit	>261 publications with PYY and CCK
POMC elisa kit	>51 publications with PYY and POMC
SST elisa kit	>9 publications with PYY and SST
NPY2R elisa kit	>6 publications with PYY and NPY2R
NPY1R elisa kit	>4 publications with PYY and NPY1R
GAL elisa kit	>3 publications with PYY and GAL
CCL28 elisa kit	>2 publications with PYY and CCL28
NPY5R elisa kit	>1 publications with PYY and NPY5R

Pathways associated with PYY elisa kit

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram

Diseases associated with PYY elisa kit

Disease Name	Pubmed Publications
Obesity Antibodies	>479 publications with PYY and Obesity
Weight Loss Antibodies	>195 publications with PYY and Weight Loss
Weight Gain Antibodies	>101 publications with PYY and Weight Gain
Insulin Resistance Antibodies	>85 publications with PYY and Insulin Resistance
Diabetes Mellitus, Type 2 Antibodies	>70 publications with PYY and Diabetes Mellitus, Type 2
Anorexia Antibodies	>66 publications with PYY and Anorexia
Hyperinsulinism Antibodies	>57 publications with PYY and Hyperinsulinism
Inflammation Antibodies	>53 publications with PYY and Inflammation
Carcinoma Antibodies	>46 publications with PYY and Carcinoma
Diarrhea Antibodies	>39 publications with PYY and Diarrhea

Organs/Tissues associated with PYY elisa kit

Organ/Tissue Name	Pubmed Publications
Intestine Antibodies	>533 publications with PYY and Intestine
Brain Antibodies	>422 publications with PYY and Brain
Kidney Antibodies	>64 publications with PYY and Kidney
Testis Antibodies	>2 publications with PYY and Testis
Uncharacterized Tissue Antibodies	>1 publications with PYY and Uncharacterized Tissue