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Pregnancy Zone (PZP) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS765601

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti-Human PZP antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Human PZP antibody was used as detection antibodies. The… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Pregnancy zone protein (PZP), ELISA Kit
Full Product Name
Human Pregnancy zone protein ELISA Kit
Product Gene Name
PZP elisa kit
Product Synonym Names
PZP/CPAMD6 (Pregnancy zone protein)/C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6/pregnancy-zone protein
Species Reactivity
Human
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
0.156-10ug/ml
Sensitivity
0.094ug/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
140,368 Da
OMIM
176420
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of PZP elisa kit

Human PZP ELISA Kit – Cat# MBS765601

Typical Standard Curve of PZP elisa kit

Human PZP ELISA Kit, Typical Standard Curve – Cat# MBS765601

Other Notes

Small volumes of PZP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PZP purchase

MBS765601 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Pregnancy zone protein (PZP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PZP. The ELISA analytical biochemical technique of the MBS765601 kit is based on PZP antibody-PZP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PZP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PZP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for PZP. It may not necessarily be applicable to this product.

NCBI GI #
162809334
NCBI GeneID
5858
NCBI Accession #
NP_002855.2
UniProt Secondary Accession #
Q15273; Q2NKL2; Q7M4N7; A6ND27
UniProt Related Accession #
P20742
GenBank Nucleotide #
NM_002864.2
NCBI Official Full Name
pregnancy zone protein
NCBI Official Synonym Full Names
pregnancy-zone protein
NCBI Official Symbol
PZP
NCBI Official Synonym Symbols
CPAMD6
UniProt Protein Name
Pregnancy zone protein
UniProt Synonym Protein Names
C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6
Protein Family
Pregnancy zone protein
UniProt Gene Name
PZP
UniProt Synonym Gene Names
CPAMD6
UniProt Entry Name
PZP_HUMAN
NCBI Protein Information
pregnancy zone protein

UniProt Comments for PZP

PZP: Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase. Belongs to the protease inhibitor I39 (alpha-2- macroglobulin) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 12p13-p12.2

Cellular Component: extracellular region

Molecular Function: endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity

Biological Process: female pregnancy
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Research Articles on PZP

1. Quantitative measurements using a multiple reaction monitoring assay showed a significant increase in plasma pregnancy-zone protein in presymptomatic Alzheimer disease compared with controls

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with PZP elisa kit

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >14 publications with PZP and Liver
 Brain Antibodies  >13 publications with PZP and Brain
 Uterus Antibodies  >5 publications with PZP and Uterus
 Lung Antibodies  >2 publications with PZP and Lung
 Trachea Antibodies  >1 publications with PZP and Trachea
 Testis Antibodies  >1 publications with PZP and Testis
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