• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Histatin-3 (HTN3) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS765609

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti-Human HTN3 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Human HTN3 antibody was used as detection antibodies. The… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Histatin-3 (HTN3), ELISA Kit
Full Product Name
Human Histatin-3 ELISA Kit
Product Gene Name
HTN3 elisa kit
Product Synonym Names
HTN3/Histatin-3/PB/Basic histidine-rich protein/Hst/Histidine-rich protein 3
Species Reactivity
Human
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
12.5-800ng/ml
Sensitivity
7.5ng/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
6,149 Da
OMIM
142702
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of HTN3 elisa kit

Human HTN3 ELISA Kit – Cat# MBS765609

Typical Standard Curve of HTN3 elisa kit

Human HTN3 ELISA Kit, Typical Standard Curve – Cat# MBS765609

Other Notes

Small volumes of HTN3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HTN3 purchase

MBS765609 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Histatin-3 (HTN3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HTN3. The ELISA analytical biochemical technique of the MBS765609 kit is based on HTN3 antibody-HTN3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HTN3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HTN3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for HTN3. It may not necessarily be applicable to this product.

NCBI GI #
4557653
NCBI GeneID
3347
NCBI Accession #
NP_000191.1
UniProt Secondary Accession #
Q16243; Q502Z1
UniProt Related Accession #
P15516
GenBank Nucleotide #
NM_000200.2
NCBI Official Full Name
histatin-3
NCBI Official Synonym Full Names
histatin 3
NCBI Official Symbol
HTN3
NCBI Official Synonym Symbols
HIS2; HTN2; HTN5
UniProt Protein Name
Histatin-3
UniProt Synonym Protein Names
Basic histidine-rich protein; Hst
Protein Family
Histatin
UniProt Gene Name
HTN3
UniProt Synonym Gene Names
HIS2; Hst; His3 20/44; His3 1/25; His3 20/43; His3 1/24; His3 20/32; His3 1/13; His3 20/31; His3 1/12; His3 20/30; His3 1/11; His3 24/32; His3 5/13; His3 24/31; His3 5/12; His3 24/30; His3 5/11; His3 25/32; His3 6/13; His3 25/30; His3 6/11; His3 26/32; Hi
UniProt Entry Name
HIS3_HUMAN
NCBI Protein Information
histatin-3

NCBI Summary for HTN3

This gene encodes a member of the histatin family of small, histidine-rich, cationic proteins. They function as antimicrobial peptides and are important components of the innate immune system. Histatins are found in saliva and exhibit antibacterial, antifungal activities and function in wound healing. [provided by RefSeq, Sep 2014]
Show more

UniProt Comments for HTN3

HTN3: Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. His3-(20-43)-peptide (histatin-5) is especially effective against C.albicans and C.neoformans, and inhibits Lys-gingipain and Arg-gingipain (rgpB) from P.gingivalis. In addition, His3-(20-43)-peptide is a potent inhibitor of metalloproteinases MMP2 and MMP9. Belongs to the histatin/statherin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 4q13

Cellular Component: extracellular region

Molecular Function: metal ion binding; protein binding

Biological Process: biomineral formation; defense response to bacterium; defense response to fungus; killing of cells of another organism
Show more

Research Articles on HTN3

1. Hst 5 may affect mitochondrial functions and cause oxidative stress; however, the ultimate cause of cell death is by volume dysregulation and ion imbalance triggered by osmotic stress. [Review]

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HTN3 elisa kit

 Reference Product  PubMed Publications
 MUC7 elisa kit  >7 publications with HTN3 and MUC7

Pathways associated with HTN3 elisa kit

 Products by Pathway  Pathway Diagram
 Salivary Secretion Pathway antibodies  Salivary Secretion Pathway Diagram
 Salivary Secretion Pathway antibodies  Salivary Secretion Pathway Diagram

Diseases associated with HTN3 elisa kit

 Disease Name  Pubmed Publications
 Hemolysis Antibodies  >4 publications with HTN3 and Hemolysis
 Necrosis Antibodies  >4 publications with HTN3 and Necrosis
 Cardiovascular Diseases Antibodies  >4 publications with HTN3 and Cardiovascular Diseases
 Inflammation Antibodies  >3 publications with HTN3 and Inflammation
 Bone Diseases Antibodies  >2 publications with HTN3 and Bone Diseases
 Infertility, Male Antibodies  >1 publications with HTN3 and Infertility, Male

Organs/Tissues associated with HTN3 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Salivary Gland Antibodies  >21 publications with HTN3 and Salivary Gland
 Uncharacterized Tissue Antibodies  >2 publications with HTN3 and Uncharacterized Tissue
 Vascular Antibodies  >2 publications with HTN3 and Vascular
 Testis Antibodies  >1 publications with HTN3 and Testis
 Connective Tissue Antibodies  >1 publications with HTN3 and Connective Tissue
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000