Rabbit Anti-A4GALT Polyclonal Antibody – Cat# MBS766246

RAW 264.7 cells were subjected to SDS PAGE followed by western blot with MBS766246 (A4GALT Antibody) at dilution of 1:1000

A4GALT Antibody – Rabbit Polyclonal

Name: A4GALT Antibody; Polyclonal; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS766246
Price: 345 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS766246

MBS766246 is an antibody targeting A4GALT. Also known as A4GALT Rabbit Polyclonal. Reactive in Human, Mouse. Host: Rabbit. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

A4GALT, Polyclonal Antibody

Full Product Name

A4GALT Rabbit Polyclonal

Product Gene Name

anti-A4GALT antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse

Form/Format

Liquid

Purity/Purification

>=95% as determined by SDS-PAGE
Immunogen Affinity Purified

Preparation and Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Molecular Weight

40,499 Da

OMIM

111400

Immunogen

Alpha 1, 4-galactosyltransferase

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-A4GALT antibody

ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-A4GALT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for A4GALT. It may not necessarily be applicable to this product.

NCBI GI #

33115183

NCBI GeneID

53947

NCBI Accession #

AAH55286.1

UniProt Secondary Accession #

Q9P1X5; B2R7C4

UniProt Related Accession #

Q9NPC4

NCBI Official Full Name

A4GALT protein

NCBI Official Synonym Full Names

alpha 1,4-galactosyltransferase

NCBI Official Symbol

A4GALT

NCBI Official Synonym Symbols

P1; PK; Gb3S; P(k); P1PK; A14GALT; A4GALT1

UniProt Protein Name

Lactosylceramide 4-alpha-galactosyltransferase

UniProt Synonym Protein Names

Alpha-1,4-N-acetylglucosaminyltransferase; Alpha-1,4-galactosyltransferase; Alpha4Gal-T1; CD77 synthase; Globotriaosylceramide synthase; Gb3 synthase; P1/Pk synthase; UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase

Protein Family

Lactosylceramide 4-alpha-galactosyltransferase

UniProt Gene Name

A4GALT

UniProt Synonym Gene Names

A14GALT; A4GALT1; Gb3 synthase

UniProt Entry Name

A4GAT_HUMAN

NCBI Protein Information

lactosylceramide 4-alpha-galactosyltransferase

NCBI Summary for A4GALT

The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. This protein, a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]

UniProt Comments for A4GALT

A4GALT: Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins. Belongs to the glycosyltransferase 32 family.

Protein type: EC 2.4.1.228; Transferase; Membrane protein, integral; Glycan Metabolism - glycosphingolipid biosynthesis - globo series

Chromosomal Location of Human Ortholog: 22q13.2

Cellular Component: integral to Golgi membrane; membrane

Molecular Function: galactosyltransferase activity; lactosylceramide 4-alpha-galactosyltransferase activity; toxin binding

Biological Process: globoside biosynthetic process; glycosphingolipid biosynthetic process; plasma membrane organization and biogenesis; protein amino acid glycosylation

Disease: Blood Group, P1pk System

Research Articles on A4GALT

1. This is the first direct biochemical evidence that Gb3/CD77 synthase is able to synthesize two different glycosphingolipid antigens: P(k) and P1, and when p.Q211E substitution is present, the NOR antigen is also synthesized.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-A4GALT antibody

Reference Product	PubMed Publications
B3GALNT1 antibody	>1 publications with A4GALT and B3GALNT1

Pathways associated with anti-A4GALT antibody

Products by Pathway	Pathway Diagram
Glycosphingolipid Biosynthesis - Globo Series Pathway antibodies	Glycosphingolipid Biosynthesis - Globo Series Pathway Diagram
Glycosphingolipid Biosynthesis - Globo Series Pathway antibodies	Glycosphingolipid Biosynthesis - Globo Series Pathway Diagram
Glycosphingolipid Biosynthesis, Globo-series, LacCer => Gb4Cer Pathway antibodies	Glycosphingolipid Biosynthesis, Globo-series, LacCer => Gb4Cer Pathway Diagram
Glycosphingolipid Biosynthesis, Globo-series, LacCer => Gb4Cer Pathway antibodies	Glycosphingolipid Biosynthesis, Globo-series, LacCer => Gb4Cer Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram

Diseases associated with anti-A4GALT antibody

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>2 publications with A4GALT and Immune System Diseases
Carcinoma Antibodies	>2 publications with A4GALT and Carcinoma
Neoplasm Metastasis Antibodies	>1 publications with A4GALT and Neoplasm Metastasis
Chromosome Aberrations Antibodies	>1 publications with A4GALT and Chromosome Aberrations
Inflammation Antibodies	>1 publications with A4GALT and Inflammation

Organs/Tissues associated with anti-A4GALT antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>1 publications with A4GALT and Bone
Ovary Antibodies	>1 publications with A4GALT and Ovary
Stomach Antibodies	>1 publications with A4GALT and Stomach
Kidney Antibodies	>1 publications with A4GALT and Kidney