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AKAP7 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS766489

MBS766489 is an antibody targeting AKAP7. Also known as AKAP7 Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AKAP7, Polyclonal Antibody
Full Product Name
AKAP7 Rabbit Polyclonal
Product Gene Name
Clonality
Polyclonal
Isotype
IgG2a
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
8,969 Da
OMIM
604693
Immunogen
A kinase (PRKA) anchor protein 7
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-AKAP7 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP)

Immunohistochemistry (IHC) of anti-AKAP7 antibody

Immunohistochemistry of paraffin-embedded human brain tissue slide using MBS766489 (AKAP7 Antibody) at dilution of 1:50
Rabbit Anti-AKAP7 Polyclonal Antibody – Cat# MBS766489

Testing Data of anti-AKAP7 antibody

Rabbit Anti-AKAP7 Polyclonal Antibody, Testing Data – Cat# MBS766489

Western Blot (WB) of anti-AKAP7 antibody

human brain tissue were subjected to SDS PAGE followed by western blot with MBS766489 (AKAP7 antibody) at dilution of 1:500
Rabbit Anti-AKAP7 Polyclonal Antibody, Western Blot (WB) – Cat# MBS766489

Other Notes

Small volumes of anti-AKAP7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AKAP7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
A-kinase anchor protein 7 isoform gamma isoform gamma
NCBI Official Synonym Full Names
A-kinase anchoring protein 7
NCBI Official Symbol
AKAP7
NCBI Official Synonym Symbols
AKAP15; AKAP18
UniProt Protein Name
A-kinase anchor protein 7 isoform gamma
UniProt Synonym Protein Names
A-kinase anchor protein 18 kDa; AKAP 18; Protein kinase A-anchoring protein 7 isoform gamma; PRKA7 isoform gamma
UniProt Gene Name
AKAP7
UniProt Synonym Gene Names
AKAP18; AKAP-7 isoform gamma; AKAP 18; PRKA7 isoform gamma
UniProt Entry Name
AKA7G_HUMAN
NCBI Protein Information
A-kinase anchor protein 7 isoform gamma

NCBI Summary for AKAP7

This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Apr 2011]
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UniProt Comments for AKAP7

AKAP7: Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures. The membrane- associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 6q23

Cellular Component: apical plasma membrane; cytosol; intracellular; lateral plasma membrane; nucleus; plasma membrane

Molecular Function: nucleotide binding; protein binding; protein kinase A binding; protein kinase binding

Biological Process: ion transport; protein localization; regulation of action potential
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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