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ALDH1L2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS766522

MBS766522 is an antibody targeting ALDH1L2. Also known as ALDH1L2 Rabbit Polyclonal. Reactive in Human, Mouse. Host: Rabbit. More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
ALDH1L2, Polyclonal Antibody
Full Product Name
ALDH1L2 Rabbit Polyclonal
Product Gene Name
anti-ALDH1L2 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
57,244 Da
OMIM
613584
Immunogen
Aldehyde dehydrogenase 1 family, member L2
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-ALDH1L2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-ALDH1L2 antibody

Immunohistochemistry of paraffin-embedded human pancreas slide using MBS766522 (ALDH1L2 Antibody) at dilution of 1:50
Rabbit Anti-ALDH1L2 Polyclonal Antibody – Cat# MBS766522

Western Blot (WB) of anti-ALDH1L2 antibody

mouse kidney tissue were subjected to SDS PAGE followed by western blot with MBS766522 (ALDH1L2 antibody) at dilution of 1:1000
Rabbit Anti-ALDH1L2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS766522

Other Notes

Small volumes of anti-ALDH1L2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ALDH1L2. It may not necessarily be applicable to this product.

NCBI GI #
74353527
NCBI GeneID
160428
NCBI Accession #
AAI03936.1
UniProt Secondary Accession #
Q3SY68; Q68D62; Q6AI55; Q8N922
UniProt Related Accession #
Q3SY69
NCBI Official Full Name
ALDH1L2 protein
NCBI Official Synonym Full Names
aldehyde dehydrogenase 1 family member L2
NCBI Official Symbol
ALDH1L2
NCBI Official Synonym Symbols
mtFDH
UniProt Protein Name
Mitochondrial 10-formyltetrahydrofolate dehydrogenase
UniProt Synonym Protein Names
Aldehyde dehydrogenase family 1 member L2
Protein Family
Mitochondrial 10-formyltetrahydrofolate dehydrogenase
UniProt Gene Name
ALDH1L2
UniProt Synonym Gene Names
Mitochondrial 10-FTHFDH; mtFDH
UniProt Entry Name
AL1L2_HUMAN
NCBI Protein Information
mitochondrial 10-formyltetrahydrofolate dehydrogenase

NCBI Summary for ALDH1L2

This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010]
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UniProt Comments for ALDH1L2

ALDH1L2: a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010]

Protein type: EC 1.5.1.6; Oxidoreductase

Chromosomal Location of Human Ortholog: 12q23.3

Cellular Component: mitochondrial matrix; mitochondrion

Molecular Function: 4-trimethylammoniobutyraldehyde dehydrogenase activity; aldehyde dehydrogenase (NAD) activity; aminobutyraldehyde dehydrogenase activity; formyltetrahydrofolate dehydrogenase activity; hydroxymethyl-, formyl- and related transferase activity

Biological Process: 10-formyltetrahydrofolate catabolic process; biosynthetic process; folic acid metabolic process; one-carbon compound metabolic process
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Research Articles on ALDH1L2

1. ALDH1L2 has enzymatic properties similar to its cytosolic counterpart

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ALDH1L2 antibody

 Products by Pathway  Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Folate And Pterines Pathway antibodies  Metabolism Of Folate And Pterines Pathway Diagram
 Metabolism Of Vitamins And Cofactors Pathway antibodies  Metabolism Of Vitamins And Cofactors Pathway Diagram
 Metabolism Of Water-soluble Vitamins And Cofactors Pathway antibodies  Metabolism Of Water-soluble Vitamins And Cofactors Pathway Diagram
 One Carbon Pool By Folate Pathway antibodies  One Carbon Pool By Folate Pathway Diagram
 One Carbon Pool By Folate Pathway antibodies  One Carbon Pool By Folate Pathway Diagram
 Folate Transformations I Pathway antibodies  Folate Transformations I Pathway Diagram

Diseases associated with anti-ALDH1L2 antibody

 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >1 publications with ALDH1L2 and Fatty Liver
 Liver Diseases Antibodies  >1 publications with ALDH1L2 and Liver Diseases
 Disease Models, Animal Antibodies  >1 publications with ALDH1L2 and Disease Models, Animal

Organs/Tissues associated with anti-ALDH1L2 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >2 publications with ALDH1L2 and Liver
 Mammary Gland Antibodies  >1 publications with ALDH1L2 and Mammary Gland
 Heart Antibodies  >1 publications with ALDH1L2 and Heart
 Pancreas Antibodies  >1 publications with ALDH1L2 and Pancreas
 Brain Antibodies  >1 publications with ALDH1L2 and Brain
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