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Aldolase C (ALDOC) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS766536

Background: Fructose-bisphosphate aldolase C(ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of… More details

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Product Overview

Online Datasheet in PDF
Product Name
Aldolase C (ALDOC), Monoclonal Antibody
Full Product Name
Aldolase C Mouse Monoclonal
Product Gene Name
anti-ALDOC antibody
Product Synonym Names
ALDOC, Aldolase C, Brain type aldolase, Fructose bisphosphate aldolase C
Clonality
Monoclonal
Isotype
IgG1
Host
Mouse
Species Reactivity
Human
Form/Format
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3,
Purity/Purification
>95% as determined by SDS-PAGE
Protein A+G purification
Preparation and Storage
Store at -20 degree C. (Avoid repeated freeze / thaw cycles.)
Molecular Weight
39 kDa
OMIM
103870
Immunogen
Aldolase C, fructose-bisphosphate
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-ALDOC antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
Application Notes for anti-ALDOC antibody
WB: 1:5000-1:50000
IHC: 1:50-1:500
IF: 1:20-1:20

Immunohistochemistry (IHC) of anti-ALDOC antibody

Immunohistochemistry of paraffin-embedded human liver tissue slide using MBS766536 (ALDOC Antibody) at dilution of 1:200 . heat mediated antigen retrieved with Tris-EDTA buffer (pH9) .
Mouse Anti-ALDOC Monoclonal Antibody – Cat# MBS766536

Western Blot (WB) of anti-ALDOC antibody

human heart tissue were subjected to SDS PAGE followed by western blot with MBS766536 (ALDOC antibody) at dilution of 1:10000
Mouse Anti-ALDOC Monoclonal Antibody, Western Blot (WB) – Cat# MBS766536

Other Notes

Small volumes of anti-ALDOC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ALDOC purchase

MBS766536 is an antibody targeting ALDOC. Also known as Aldolase C Mouse Monoclonal. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ALDOC. It may not necessarily be applicable to this product.

NCBI GI #
3005698
NCBI GeneID
230
NCBI Accession #
AAC09348.1
UniProt Secondary Accession #
Q3SYL3; Q6FH94; Q6P0L5; B2R5R3
UniProt Related Accession #
P09972
NCBI Official Full Name
aldolase C
NCBI Official Synonym Full Names
aldolase, fructose-bisphosphate C
NCBI Official Symbol
ALDOC
NCBI Official Synonym Symbols
ALDC
UniProt Protein Name
Fructose-bisphosphate aldolase C
UniProt Synonym Protein Names
Brain-type aldolase
Protein Family
Fructose-bisphosphate aldolase
UniProt Gene Name
ALDOC
UniProt Synonym Gene Names
ALDC
UniProt Entry Name
ALDOC_HUMAN
NCBI Protein Information
fructose-bisphosphate aldolase C

NCBI Summary for ALDOC

This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]
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UniProt Comments for ALDOC

ALDOC: a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]

Protein type: EC 4.1.2.13; Lyase; Carbohydrate Metabolism - pentose phosphate pathway; Carbohydrate Metabolism - fructose and mannose; Carbohydrate Metabolism - glycolysis and gluconeogenesis

Chromosomal Location of Human Ortholog: 17cen-q12

Cellular Component: cytoskeleton; cytosol; mitochondrion

Molecular Function: cytoskeletal protein binding; fructose-bisphosphate aldolase activity; protein binding

Biological Process: epithelial cell differentiation; fructose 1,6-bisphosphate metabolic process; fructose metabolic process; gluconeogenesis
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Research Articles on ALDOC

1. ALDOC, Aldolase A (ALDOA) and Aldolase B (ALDOB) activate Wnt signaling.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ALDOC antibody

 Products by Pathway  Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Fructose And Mannose Metabolism Pathway antibodies  Fructose And Mannose Metabolism Pathway Diagram
 Fructose And Mannose Metabolism Pathway antibodies  Fructose And Mannose Metabolism Pathway Diagram
 Gluconeogenesis Pathway antibodies  Gluconeogenesis Pathway Diagram
 Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway antibodies  Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway Diagram
 Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway antibodies  Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway Diagram
 Glucose Metabolism Pathway antibodies  Glucose Metabolism Pathway Diagram

Diseases associated with anti-ALDOC antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >3 publications with ALDOC and Nervous System Diseases
 Weight Loss Antibodies  >3 publications with ALDOC and Weight Loss
 Brain Diseases Antibodies  >2 publications with ALDOC and Brain Diseases
 Disease Models, Animal Antibodies  >2 publications with ALDOC and Disease Models, Animal
 Necrosis Antibodies  >2 publications with ALDOC and Necrosis
 Abnormalities, Drug-Induced Antibodies  >1 publications with ALDOC and Abnormalities, Drug-Induced
 Ovarian Neoplasms Antibodies  >1 publications with ALDOC and Ovarian Neoplasms
 Nerve Degeneration Antibodies  >1 publications with ALDOC and Nerve Degeneration
 Inflammation Antibodies  >1 publications with ALDOC and Inflammation

Organs/Tissues associated with anti-ALDOC antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >11 publications with ALDOC and Brain
 Blood Antibodies  >5 publications with ALDOC and Blood
 Eye Antibodies  >4 publications with ALDOC and Eye
 Adipose Tissue Antibodies  >3 publications with ALDOC and Adipose Tissue
 Muscle Antibodies  >3 publications with ALDOC and Muscle
 Nerve Antibodies  >2 publications with ALDOC and Nerve
 Ganglia Antibodies  >1 publications with ALDOC and Ganglia
 Bone Antibodies  >1 publications with ALDOC and Bone
 Placenta Antibodies  >1 publications with ALDOC and Placenta
 Vascular Antibodies  >1 publications with ALDOC and Vascular
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