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AMACR/p504S Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS766587

MBS766587 is an antibody targeting AMACR/p504S. Also known as AMACR/p504S Rabbit Polyclonal. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AMACR/p504S, Polyclonal Antibody
Full Product Name
AMACR/p504S Rabbit Polyclonal
Product Gene Name
anti-AMACR/p504S antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
41,828 Da
Immunogen
Alpha-methylacyl-CoA racemase
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-AMACR/p504S antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)

Immunohistochemistry (IHC) of anti-AMACR/p504S antibody

Immunohistochemistry of paraffin-embedded human prostate cancer using MBS766587 (p50S,AMACR antibody) at dilution of 1:50
Rabbit Anti-AMACR/p504S Polyclonal Antibody – Cat# MBS766587

Western Blot (WB) of anti-AMACR/p504S antibody

Recombinant AMACR protein were subjected to SDS PAGE followed by western blot with MBS766587 (AMACR Antibody) at dilution of 1:1000
Rabbit Anti-AMACR/p504S Polyclonal Antibody, Western Blot (WB) – Cat# MBS766587

Other Notes

Small volumes of anti-AMACR/p504S antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AMACR/p504S. It may not necessarily be applicable to this product.

NCBI GI #
401709963
NCBI GeneID
25284
NCBI Accession #
NP_036948.2
UniProt Secondary Accession #
O09176
UniProt Related Accession #
P70473
GenBank Nucleotide #
NM_012816.2
NCBI Official Full Name
alpha-methylacyl-CoA racemase
NCBI Official Synonym Full Names
alpha-methylacyl-CoA racemase
NCBI Official Symbol
Amacr
NCBI Official Synonym Symbols
Da1-8; Marc1
UniProt Protein Name
Alpha-methylacyl-CoA racemase
UniProt Synonym Protein Names
2-arylpropionyl-CoA epimerase; 2-methylacyl-CoA racemase
UniProt Gene Name
Amacr
UniProt Entry Name
AMACR_RAT
NCBI Protein Information
alpha-methylacyl-CoA racemase

NCBI Summary for AMACR/p504S

enzmyme that converts pristanoyl-CoA and C27-bile acyl-CoAs to (S)-stereoisomers; involved in the degradation of the side chain of bile acid intermediates [RGD, Feb 2006]

UniProt Comments for AMACR/p504S

AMACR: Racemization of 2-methyl-branched fatty acid CoA esters. Responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers. Has a role in drug metabolism as well as probably in lipid metabolism. The 2-arylpropionic acid (2-APA's) derivatives, including ibuprofen, are the most widely used anti-inflammatory analgesic cyclooxygenase inhibitors. The (-)-R-enantiomer, which is inactive in terms of cyclooxygenase inhibition, is epimerized in vivo via this enzyme to the cyclooxygenase-inhibiting (+)-S-enantiomer

Protein type: Mitochondrial; Lipid Metabolism - primary bile acid biosynthesis; Isomerase; EC 5.1.99.4

Cellular Component: cytoplasm; mitochondrion; peroxisome

Molecular Function: alpha-methylacyl-CoA racemase activity; catalytic activity; receptor binding

Biological Process: bile acid biosynthetic process; bile acid metabolic process; fatty acid metabolic process
Show more

Research Articles on AMACR/p504S

1. role of alpha-methylacyl-CoA racemase in bile acid synthesis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AMACR/p504S antibody

 Reference Product  PubMed Publications
 Acox3 antibody  >1 publications with AMACR/p504S and Acox3
 Acox2 antibody  >1 publications with AMACR/p504S and Acox2

Pathways associated with anti-AMACR/p504S antibody

 Products by Pathway  Pathway Diagram
 Beta-oxidation Of Pristanoyl-CoA Pathway antibodies  Beta-oxidation Of Pristanoyl-CoA Pathway Diagram
 Bile Acid And Bile Salt Metabolism Pathway antibodies  Bile Acid And Bile Salt Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 PKC-SCP2 Pathway antibodies  PKC-SCP2 Pathway Diagram
 Peroxisomal Lipid Metabolism Pathway antibodies  Peroxisomal Lipid Metabolism Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Primary Bile Acid Biosynthesis Pathway antibodies  Primary Bile Acid Biosynthesis Pathway Diagram

Organs/Tissues associated with anti-AMACR/p504S antibody

 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >262 publications with AMACR/p504S and Prostate
 Kidney Antibodies  >90 publications with AMACR/p504S and Kidney
 Liver Antibodies  >18 publications with AMACR/p504S and Liver
 Muscle Antibodies  >10 publications with AMACR/p504S and Muscle
 Ovary Antibodies  >6 publications with AMACR/p504S and Ovary
 Brain Antibodies  >4 publications with AMACR/p504S and Brain
 Heart Antibodies  >1 publications with AMACR/p504S and Heart
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