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AMPD3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS766604

MBS766604 is an antibody targeting AMPD3. Also known as AMPD3 Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AMPD3, Polyclonal Antibody
Full Product Name
AMPD3 Rabbit Polyclonal
Product Gene Name
anti-AMPD3 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
88,652 Da
Immunogen
Adenosine monophosphate deaminase (isoform E)
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-AMPD3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-AMPD3 antibody

Immunohistochemistry of paraffin-embedded human placenta tissue slide using MBS766604 (AMPD3 Antibody) at dilution of 1:50
Rabbit Anti-AMPD3 Polyclonal Antibody – Cat# MBS766604

Western Blot (WB) of anti-AMPD3 antibody

mouse kidney tissue were subjected to SDS PAGE followed by western blot with MBS766604 (AMPD3 antibody) at dilution of 1:1000
Rabbit Anti-AMPD3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS766604

Other Notes

Small volumes of anti-AMPD3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AMPD3. It may not necessarily be applicable to this product.

NCBI GI #
444189292
NCBI GeneID
11717
NCBI Accession #
NP_001263230.1
UniProt Secondary Accession #
O88692; Q8CFR4
UniProt Related Accession #
O08739
GenBank Nucleotide #
NM_001276301.1
NCBI Official Full Name
AMP deaminase 3
NCBI Official Synonym Full Names
adenosine monophosphate deaminase 3
NCBI Official Symbol
Ampd3
UniProt Protein Name
AMP deaminase 3
UniProt Synonym Protein Names
AMP deaminase H-type; AMP deaminase isoform E; Heart-type AMPD
Protein Family
AMP deaminase
UniProt Gene Name
Ampd3
UniProt Entry Name
AMPD3_MOUSE
NCBI Protein Information
AMP deaminase 3

NCBI Summary for AMPD3

This gene encodes a member of the adenosine and AMP deaminases family. The encoded protein is an AMP deaminase involved in nucleotide and energy metabolism in erythrocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

UniProt Comments for AMPD3

AMPD3: AMP deaminase plays a critical role in energy metabolism. Defects in AMPD3 are the cause of adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE); also known as erythrocyte AMP deaminase deficiency. AMPDDE is a metabolic disorder due to lack of activity of the erythrocyte isoform of AMP deaminase. It is a clinically asymptomatic condition characterized by a 50% increase in steady-state levels of ATP in affected cells. Individuals with complete deficiency of erythrocyte AMP deaminase are healthy and have no hematologic disorders. Belongs to the adenosine and AMP deaminases family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.5.4.6; Nucleotide Metabolism - purine; Hydrolase

Molecular Function: AMP deaminase activity; deaminase activity; hydrolase activity; metal ion binding

Biological Process: ADP metabolic process; AMP metabolic process; ATP metabolic process; erythrocyte homeostasis; GTP metabolic process; IMP biosynthetic process; IMP salvage; nucleotide metabolic process; purine ribonucleoside monophosphate biosynthetic process
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Research Articles on AMPD3

1. effect of AMP-deaminase 3 knock-out in mice on enzyme activity in heart and other organs

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-AMPD3 antibody

 Products by Pathway  Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Nucleotides Pathway antibodies  Metabolism Of Nucleotides Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Salvage Pathway antibodies  Purine Salvage Pathway Diagram

Diseases associated with anti-AMPD3 antibody

 Disease Name  Pubmed Publications
 Lung Injury Antibodies  >3 publications with AMPD3 and Lung Injury
 Inflammation Antibodies  >3 publications with AMPD3 and Inflammation
 Carcinoma, Hepatocellular Antibodies  >1 publications with AMPD3 and Carcinoma, Hepatocellular
 Hemorrhage Antibodies  >1 publications with AMPD3 and Hemorrhage
 Liver Neoplasms Antibodies  >1 publications with AMPD3 and Liver Neoplasms
 Lung Neoplasms Antibodies  >1 publications with AMPD3 and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >1 publications with AMPD3 and Neoplasms, Experimental
 Liver Diseases Antibodies  >1 publications with AMPD3 and Liver Diseases
 Fibrosis Antibodies  >1 publications with AMPD3 and Fibrosis
 Necrosis Antibodies  >1 publications with AMPD3 and Necrosis

Organs/Tissues associated with anti-AMPD3 antibody

 Organ/Tissue Name  Pubmed Publications
 Other Antibodies  >10 publications with AMPD3 and Other
 Lung Antibodies  >5 publications with AMPD3 and Lung
 Embryonic Tissue Antibodies  >2 publications with AMPD3 and Embryonic Tissue
 Brain Antibodies  >2 publications with AMPD3 and Brain
 Lymph Node Antibodies  >1 publications with AMPD3 and Lymph Node
 Eye Antibodies  >1 publications with AMPD3 and Eye
 Kidney Antibodies  >1 publications with AMPD3 and Kidney
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