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Annexin VI (ANXA6) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS766670

MBS766670 is an antibody targeting ANXA6. Also known as Annexin VI Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Annexin VI (ANXA6), Polyclonal Antibody
Full Product Name
Annexin VI Rabbit Polyclonal
Product Gene Name
anti-ANXA6 antibody
Clonality
Polyclonal
Isotype
IgG1
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
75,907 Da
Immunogen
Annexin A6
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-ANXA6 antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB), Immunoprecipitation (IP)

Immunohistochemistry (IHC) of anti-ANXA6 antibody

Immunohistochemistry of paraffin-embedded human colon cancer using MBS766670 (ANXA6 antibody) at dilution of 1:100
Rabbit Anti-ANXA6 Polyclonal Antibody – Cat# MBS766670

Immunoprecipitation (IP) of anti-ANXA6 antibody

IP Result of anti-ANXA6 (IP: MBS766670, 4ug; Detection: MBS766670 1:500) with mouse kidney tissue lysate 4000ug.
Rabbit Anti-ANXA6 Polyclonal Antibody, Immunoprecipitation (IP) – Cat# MBS766670

Western Blot (WB) of anti-ANXA6 antibody

HeLa cells were subjected to SDS PAGE followed by western blot with MBS766670 (ANXA6 Antibody) at dilution of 1:1000
Rabbit Anti-ANXA6 Polyclonal Antibody, Western Blot (WB) – Cat# MBS766670

Other Notes

Small volumes of anti-ANXA6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ANXA6. It may not necessarily be applicable to this product.

NCBI GI #
157151716
NCBI GeneID
327685
NCBI Accession #
NP_001096694.1
UniProt Secondary Accession #
A7YY61
UniProt Related Accession #
P79134
GenBank Nucleotide #
NM_001103224.1
NCBI Official Full Name
annexin A6
NCBI Official Symbol
ANXA6
UniProt Protein Name
Annexin A6
UniProt Synonym Protein Names
Annexin VI; Annexin-6
Protein Family
Annexin
UniProt Gene Name
ANXA6
UniProt Synonym Gene Names
ANX6
UniProt Entry Name
ANXA6_BOVIN
NCBI Protein Information
annexin A6

UniProt Comments for ANXA6

ANXA2: a calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. Heterotetramer containing 2 light chains of S100A10 2 heavy chains of ANXA2. May cross-link plasma membrane phospholipids with actin and the cytoskeleton and be involved with exocytosis. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.

Protein type: Lipid-binding; Motility/polarity/chemotaxis; Calcium-binding

Cellular Component: basement membrane

Molecular Function: calcium ion binding; calcium-dependent phospholipid binding; cytoskeletal protein binding; phospholipase inhibitor activity

Biological Process: negative regulation of catalytic activity
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Research Articles on ANXA6

1. AnxA6 is a novel receptor that mediates the endocytosis of bovine beta-glucuronidase.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ANXA6 antibody

 Reference Product  PubMed Publications
 EGFR antibody  >9 publications with ANXA6 and EGFR
 NPC1 antibody  >4 publications with ANXA6 and NPC1
 RUNX2 antibody  >1 publications with ANXA6 and RUNX2

Pathways associated with anti-ANXA6 antibody

 Products by Pathway  Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Prostaglandin Synthesis And Regulation Pathway antibodies  Prostaglandin Synthesis And Regulation Pathway Diagram

Diseases associated with anti-ANXA6 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >6 publications with ANXA6 and Nervous System Diseases
 Carcinoma Antibodies  >4 publications with ANXA6 and Carcinoma
 Inflammation Antibodies  >4 publications with ANXA6 and Inflammation
 Necrosis Antibodies  >4 publications with ANXA6 and Necrosis
 Hypertrophy Antibodies  >3 publications with ANXA6 and Hypertrophy
 Heart Diseases Antibodies  >3 publications with ANXA6 and Heart Diseases
 Neoplasm Metastasis Antibodies  >3 publications with ANXA6 and Neoplasm Metastasis
 Neoplasms, Experimental Antibodies  >2 publications with ANXA6 and Neoplasms, Experimental
 Poisoning Antibodies  >1 publications with ANXA6 and Poisoning
 Liver Diseases Antibodies  >1 publications with ANXA6 and Liver Diseases

Organs/Tissues associated with anti-ANXA6 antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >6 publications with ANXA6 and Skin
 Muscle Antibodies  >6 publications with ANXA6 and Muscle
 Cartilage Antibodies  >3 publications with ANXA6 and Cartilage
 Reticulum Antibodies  >3 publications with ANXA6 and Reticulum
 Liver Antibodies  >3 publications with ANXA6 and Liver
 Ovary Antibodies  >2 publications with ANXA6 and Ovary
 Uterus Antibodies  >2 publications with ANXA6 and Uterus
 Adrenal Gland Antibodies  >1 publications with ANXA6 and Adrenal Gland
 Lung Antibodies  >1 publications with ANXA6 and Lung
 Testis Antibodies  >1 publications with ANXA6 and Testis
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