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ANP32B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS766678

MBS766678 is an antibody targeting ANP32B. Also known as ANP32B Rabbit Polyclonal. Reactive in Human, Mouse. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
ANP32B, Polyclonal Antibody
Full Product Name
ANP32B Rabbit Polyclonal
Product Gene Name
anti-ANP32B antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
22,277 Da
Immunogen
Acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-ANP32B antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Immunohistochemistry (IHC) of anti-ANP32B antibody

Immunohistochemistry of paraffin-embedded human pancreas cancer using MBS766678 (ANP32B antibody) at dilution of 1:100
Rabbit Anti-ANP32B Polyclonal Antibody – Cat# MBS766678

Testing Data of anti-ANP32B antibody

Rabbit Anti-ANP32B Polyclonal Antibody, Testing Data – Cat# MBS766678

Western Blot (WB) of anti-ANP32B antibody

HEK-293 cells were subjected to SDS PAGE followed by western blot with MBS766678 (ANP32B antibody) at dilution of 1:1000
Rabbit Anti-ANP32B Polyclonal Antibody, Western Blot (WB) – Cat# MBS766678

Other Notes

Small volumes of anti-ANP32B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ANP32B. It may not necessarily be applicable to this product.

NCBI GI #
5454088
NCBI GeneID
10541
NCBI Accession #
NP_006392.1
UniProt Secondary Accession #
O00655; P78458; P78459; B2R9C7
UniProt Related Accession #
Q92688
GenBank Nucleotide #
NM_006401.2
NCBI Official Full Name
acidic leucine-rich nuclear phosphoprotein 32 family member B
NCBI Official Synonym Full Names
acidic nuclear phosphoprotein 32 family member B
NCBI Official Symbol
ANP32B
NCBI Official Synonym Symbols
APRIL; SSP29; PHAPI2
UniProt Protein Name
Acidic leucine-rich nuclear phosphoprotein 32 family member B
UniProt Synonym Protein Names
Acidic protein rich in leucines; Putative HLA-DR-associated protein I-2; PHAPI2; Silver-stainable protein SSP29
Protein Family
Acidic leucine-rich nuclear phosphoprotein 32 family
UniProt Gene Name
ANP32B
UniProt Synonym Gene Names
APRIL; PHAPI2; PHAPI2
UniProt Entry Name
AN32B_HUMAN
NCBI Protein Information
acidic leucine-rich nuclear phosphoprotein 32 family member B

UniProt Comments for ANP32B

ANP32B: Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity. Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome. Belongs to the ANP32 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 9q22.32

Cellular Component: cytoplasm; nucleolus; nucleus

Molecular Function: histone binding; protein binding

Biological Process: caspase activation; inner ear development; negative regulation of cell differentiation; nucleosome assembly; palate development; positive regulation of protein export from nucleus; vasculature development; ventricular system development
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Research Articles on ANP32B

1. Caspase-3-resistant uncleavable form of acidic leucine-rich nuclear phosphoprotein 32B potentiates leukemic cell apoptosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ANP32B antibody

 Reference Product  PubMed Publications
 ELAVL1 antibody  >8 publications with ANP32B and ELAVL1
 KLF5 antibody  >1 publications with ANP32B and KLF5

Diseases associated with anti-ANP32B antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >29 publications with ANP32B and Necrosis
 Inflammation Antibodies  >7 publications with ANP32B and Inflammation
 Nervous System Diseases Antibodies  >4 publications with ANP32B and Nervous System Diseases
 Cell Transformation, Neoplastic Antibodies  >1 publications with ANP32B and Cell Transformation, Neoplastic
 Breast Neoplasms Antibodies  >1 publications with ANP32B and Breast Neoplasms
 Urinary Bladder Neoplasms Antibodies  >1 publications with ANP32B and Urinary Bladder Neoplasms
 Liver Neoplasms Antibodies  >1 publications with ANP32B and Liver Neoplasms
 Disease Models, Animal Antibodies  >1 publications with ANP32B and Disease Models, Animal
 Hyperplasia Antibodies  >1 publications with ANP32B and Hyperplasia
 Heart Diseases Antibodies  >1 publications with ANP32B and Heart Diseases

Organs/Tissues associated with anti-ANP32B antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >25 publications with ANP32B and Blood
 Nerve Antibodies  >6 publications with ANP32B and Nerve
 Brain Antibodies  >5 publications with ANP32B and Brain
 Spleen Antibodies  >3 publications with ANP32B and Spleen
 Bone Antibodies  >2 publications with ANP32B and Bone
 Bone Marrow Antibodies  >2 publications with ANP32B and Bone Marrow
 Embryonic Tissue Antibodies  >2 publications with ANP32B and Embryonic Tissue
 Heart Antibodies  >1 publications with ANP32B and Heart
 Muscle Antibodies  >1 publications with ANP32B and Muscle
 Prostate Antibodies  >1 publications with ANP32B and Prostate
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