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APOBEC3C Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS766726

MBS766726 is an antibody targeting APOBEC3C. Also known as APOBEC3C Rabbit Polyclonal. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
APOBEC3C, Polyclonal Antibody
Full Product Name
APOBEC3C Rabbit Polyclonal
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
22,826 Da
OMIM
607750
Immunogen
Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-APOBEC3C antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)

Immunohistochemistry (IHC) of anti-APOBEC3C antibody

Immunohistochemistry of paraffin-embedded human ovary tumor tissue slide using MBS766726 (APOBEC3C Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer (pH9) .
Rabbit Anti-APOBEC3C Polyclonal Antibody – Cat# MBS766726

Western Blot (WB) of anti-APOBEC3C antibody

Human peripheral blood leukocyte cells were subjected to SDS PAGE followed by western blot with MBS766726 (APOBEC3C Antibody) at dilution of 1:1000
Rabbit Anti-APOBEC3C Polyclonal Antibody, Western Blot (WB) – Cat# MBS766726

Other Notes

Small volumes of anti-APOBEC3C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for APOBEC3C. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C, isoform CRA_b
NCBI Official Synonym Full Names
apolipoprotein B mRNA editing enzyme catalytic subunit 3C
NCBI Official Symbol
APOBEC3C
NCBI Official Synonym Symbols
A3C; PBI; ARP5; ARDC2; ARDC4; APOBEC1L; bK150C2.3
UniProt Protein Name
DNA dC->dU-editing enzyme APOBEC-3C
UniProt Synonym Protein Names
APOBEC1-like; Phorbolin I
UniProt Gene Name
APOBEC3C
UniProt Synonym Gene Names
APOBEC1L; PBI; A3C
UniProt Entry Name
ABC3C_HUMAN
NCBI Protein Information
DNA dC->dU-editing enzyme APOBEC-3C

NCBI Summary for APOBEC3C

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. [provided by RefSeq, Jul 2008]
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UniProt Comments for APOBEC3C

APOBEC3C: Host cellular restriction factor that may have antiviral activities against exogenous and endogenous viruses, as well as retrotransposons. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. Belongs to the cytidine and deoxycytidylate deaminase family.

Protein type: RNA-binding; Hydrolase; EC 3.5.4.-

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: cytoplasm; nucleus

Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; protein binding; zinc ion binding

Biological Process: cytidine deamination; defense response to virus; innate immune response; negative regulation of viral genome replication; viral reproduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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