• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

ARHGAP21 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS766782

MBS766782 is an antibody targeting ARHGAP21. Also known as ARHGAP21 Rabbit Polyclonal. Reactive in Human, Rat. Host: Rabbit. More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
ARHGAP21, Polyclonal Antibody
Full Product Name
ARHGAP21 Rabbit Polyclonal
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
129,244 Da
OMIM
609870
Immunogen
Rho GTPase activating protein 21
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-ARHGAP21 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-ARHGAP21 antibody

Immunohistochemistry of paraffin-embedded human ovary tissue slide using MBS766782 (ARHGAP21 Antibody) at dilution of 1:50
Rabbit Anti-ARHGAP21 Polyclonal Antibody – Cat# MBS766782

Western Blot (WB) of anti-ARHGAP21 antibody

PC-3 cells were subjected to SDS PAGE followed by western blot with MBS766782 (ARHGAP21 Antibody) at dilution of 1:600
Rabbit Anti-ARHGAP21 Polyclonal Antibody, Western Blot (WB) – Cat# MBS766782

Other Notes

Small volumes of anti-ARHGAP21 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ARHGAP21. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ARHGAP21 protein
NCBI Official Synonym Full Names
Rho GTPase activating protein 21
NCBI Official Symbol
ARHGAP21
NCBI Official Synonym Symbols
ARHGAP10
UniProt Protein Name
Rho GTPase-activating protein 21
UniProt Synonym Protein Names
Rho GTPase-activating protein 10; Rho-type GTPase-activating protein 21
UniProt Gene Name
ARHGAP21
UniProt Synonym Gene Names
ARHGAP10; KIAA1424
UniProt Entry Name
RHG21_HUMAN
NCBI Protein Information
rho GTPase-activating protein 21

NCBI Summary for ARHGAP21

ARHGAP21 functions preferentially as a GTPase-activating protein (GAP) for CDC42 (MIM 116952) and regulates the ARP2/3 complex (MIM 604221) and F-actin dynamics at the Golgi through control of CDC42 activity (Dubois et al., 2005 [PubMed 15793564]).[supplied by OMIM, Mar 2008]

UniProt Comments for ARHGAP21

ARHGAP21: Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also required for CTNNA1 recruitment to adherens junctions. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs, Rac/Rho; GAPs

Chromosomal Location of Human Ortholog: 10p12.1|10p12.3

Cellular Component: cell junction; cytoplasmic vesicle membrane; cytoskeleton; Golgi apparatus; Golgi membrane

Molecular Function: GTPase activator activity; protein binding

Biological Process: establishment of Golgi localization; Golgi organization and biogenesis; maintenance of Golgi localization; positive regulation of GTPase activity; signal transduction
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000