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ATPIF1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS766967

MBS766967 is an antibody targeting ATPIF1. Also known as ATPIF1 Rabbit Polyclonal. Reactive in Human, Mouse. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
ATPIF1, Polyclonal Antibody
Full Product Name
ATPIF1 Rabbit Polyclonal
Product Gene Name
anti-ATPIF1 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
6,592 Da
OMIM
614981
Immunogen
ATPase inhibitory factor 1
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-ATPIF1 antibody
ELISA (EIA), Western Blot (WB)

Immunohistochemistry (IHC) of anti-ATPIF1 antibody

Immunohistochemistry of paraffin-embedded human stomach using MBS766967 (ATPIF1 antibody) at dilution of 1:100
Rabbit Anti-ATPIF1 Polyclonal Antibody – Cat# MBS766967

Western Blot (WB) of anti-ATPIF1 antibody

human liver tissue were subjected to SDS PAGE followed by western blot with MBS766967 (ATPIF1 antibody) at dilution of 1:1000
Rabbit Anti-ATPIF1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS766967

Other Notes

Small volumes of anti-ATPIF1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ATPIF1. It may not necessarily be applicable to this product.

NCBI GI #
30260192
NCBI GeneID
93974
NCBI Accession #
NP_835498.1
UniProt Secondary Accession #
Q5JXL8; Q6IAQ7; Q9BSL9
UniProt Related Accession #
Q9UII2
GenBank Nucleotide #
NM_178191.2
NCBI Official Full Name
ATPase inhibitor, mitochondrial isoform 3
NCBI Official Synonym Full Names
ATPase inhibitory factor 1
NCBI Official Symbol
ATPIF1
NCBI Official Synonym Symbols
IP; ATPI; ATPIP
UniProt Protein Name
ATPase inhibitor, mitochondrial
UniProt Synonym Protein Names
Inhibitor of F(1)F(o)-ATPase; IF(1); IF1
Protein Family
ATPase inhibitor
UniProt Gene Name
ATPIF1
UniProt Synonym Gene Names
ATPI; IF(1); IF1
UniProt Entry Name
ATIF1_HUMAN
NCBI Protein Information
ATPase inhibitor, mitochondrial

NCBI Summary for ATPIF1

This gene encodes a mitochondrial ATPase inhibitor. Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

UniProt Comments for ATPIF1

ATPIF1: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Homodimer at a pH value below 6.5, inactive homotetramer above. Belongs to the ATPase inhibitor family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Inhibitor

Chromosomal Location of Human Ortholog: 1p35.3

Cellular Component: cell surface; mitochondrial proton-transporting ATP synthase complex; mitochondrion

Molecular Function: 5-formyltetrahydrofolate cyclo-ligase activity; angiostatin binding; ATPase binding; ATPase inhibitor activity; calmodulin binding; enzyme inhibitor activity; protein homodimerization activity

Biological Process: angiogenesis; erythrocyte differentiation; folic acid and derivative biosynthetic process; generation of precursor metabolites and energy; heme biosynthetic process; mitochondrial depolarization; negative regulation of ATPase activity; negative regulation of endothelial cell proliferation; negative regulation of hydrolase activity; protein homooligomerization; protein homotetramerization
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Research Articles on ATPIF1

1. These results indicate that IF1 may serve as a prognostic marker and promotes tumor growth and metastasis in gastric cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ATPIF1 antibody

 Products by Pathway  Pathway Diagram
 Electron Transport Chain Pathway antibodies  Electron Transport Chain Pathway Diagram

Diseases associated with anti-ATPIF1 antibody

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >1 publications with ATPIF1 and Disease Models, Animal
 Inflammation Antibodies  >1 publications with ATPIF1 and Inflammation
 Necrosis Antibodies  >1 publications with ATPIF1 and Necrosis

Organs/Tissues associated with anti-ATPIF1 antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1 publications with ATPIF1 and Bone
 Lymph Antibodies  >1 publications with ATPIF1 and Lymph
 Lymph Node Antibodies  >1 publications with ATPIF1 and Lymph Node
 Blood Antibodies  >1 publications with ATPIF1 and Blood
 Bone Marrow Antibodies  >1 publications with ATPIF1 and Bone Marrow
 Brain Antibodies  >1 publications with ATPIF1 and Brain
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