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AUTS2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS766982

MBS766982 is an antibody targeting AUTS2. Also known as AUTS2 Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AUTS2, Polyclonal Antibody
Full Product Name
AUTS2 Rabbit Polyclonal
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
75,998 Da
OMIM
607270
Immunogen
Autism susceptibility candidate 2
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-AUTS2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-AUTS2 antibody

Immunohistochemistry of paraffin-embedded human testis tissue slide using MBS766982 (AUTS2 Antibody) at dilution of 1:50
Rabbit Anti-AUTS2 Polyclonal Antibody – Cat# MBS766982

Western Blot (WB) of anti-AUTS2 antibody

C6 cells were subjected to SDS PAGE followed by western blot with MBS766982 (AUTS2 Antibody) at dilution of 1:600
Rabbit Anti-AUTS2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS766982

Other Notes

Small volumes of anti-AUTS2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AUTS2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
autism susceptibility gene 2 protein isoform 2
NCBI Official Synonym Full Names
autism susceptibility candidate 2
NCBI Official Symbol
AUTS2
NCBI Official Synonym Symbols
MRD26; FBRSL2
UniProt Protein Name
Autism susceptibility gene 2 protein
UniProt Gene Name
AUTS2
UniProt Synonym Gene Names
KIAA0442
UniProt Entry Name
AUTS2_HUMAN
NCBI Protein Information
autism susceptibility gene 2 protein

NCBI Summary for AUTS2

This gene has been implicated in neurodevelopment and as a candidate gene for numerous neurological disorders, including autism spectrum disorders, intellectual disability, and developmental delay. Mutations in this gene have also been associated with non-neurological disorders, such as acute lymphoblastic leukemia, aging of the skin, early-onset androgenetic alopecia, and certain cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2014]
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UniProt Comments for AUTS2

AUTS2: encoded by an autism susceptibility gene. Strongly expressed in brain, skeletal muscle and kidney. Also expressed in placenta, lung and leukocytes. The gene is interrupted by a translocation breakpoint in a pair of autistic twins. Two alternatively-spliced isoforms have been described.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 7q11.22

Cellular Component: nucleus

Molecular Function: chromatin binding

Biological Process: positive regulation of histone H3-K4 methylation; positive regulation of transcription from RNA polymerase II promoter; righting reflex

Disease: Mental Retardation, Autosomal Dominant 26
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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