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BHMT Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS767122

MBS767122 is an antibody targeting BHMT. Also known as BHMT Rabbit Polyclonal. Reactive in Human, Mouse. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
BHMT, Polyclonal Antibody
Full Product Name
BHMT Rabbit Polyclonal
Product Gene Name
anti-BHMT antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
44,998 Da
OMIM
602888
Immunogen
Betaine-homocysteine methyltransferase
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-BHMT antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Immunohistochemistry (IHC) of anti-BHMT antibody

Immunohistochemistry of paraffin-embedded human spleen using MBS767122 (BHMT antibody) at dilution of 1:100
Rabbit Anti-BHMT Polyclonal Antibody – Cat# MBS767122

Testing Data of anti-BHMT antibody

Rabbit Anti-BHMT Polyclonal Antibody, Testing Data – Cat# MBS767122

Western Blot (WB) of anti-BHMT antibody

human kidney tissue were subjected to SDS PAGE followed by western blot with MBS767122 (BHMT antibody) at dilution of 1:2000
Rabbit Anti-BHMT Polyclonal Antibody, Western Blot (WB) – Cat# MBS767122

Other Notes

Small volumes of anti-BHMT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BHMT. It may not necessarily be applicable to this product.

NCBI GI #
157266337
NCBI GeneID
635
NCBI Accession #
NP_001704.2
UniProt Secondary Accession #
Q9UNI9
UniProt Related Accession #
Q93088
GenBank Nucleotide #
NM_001713.2
NCBI Official Full Name
betaine--homocysteine S-methyltransferase 1
NCBI Official Synonym Full Names
betaine--homocysteine S-methyltransferase
NCBI Official Symbol
BHMT
NCBI Official Synonym Symbols
BHMT1; HEL-S-61p
UniProt Protein Name
Betaine--homocysteine S-methyltransferase 1
Protein Family
Betaine--homocysteine S-methyltransferase
UniProt Gene Name
BHMT
UniProt Entry Name
BHMT1_HUMAN
NCBI Protein Information
betaine--homocysteine S-methyltransferase 1

NCBI Summary for BHMT

This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed. [provided by RefSeq, Jul 2008]

UniProt Comments for BHMT

BHMT: Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline.

Protein type: Amino Acid Metabolism - cysteine and methionine; EC 2.1.1.5; Amino Acid Metabolism - glycine, serine and threonine; Methyltransferase

Chromosomal Location of Human Ortholog: 5q14.1

Cellular Component: cytoplasm; cytosol

Molecular Function: betaine-homocysteine S-methyltransferase activity; homocysteine S-methyltransferase activity; zinc ion binding

Biological Process: betaine catabolic process; betaine metabolic process; choline catabolic process; protein amino acid methylation; regulation of homocysteine metabolic process; S-adenosylmethionine metabolic process; sulfur amino acid metabolic process
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Research Articles on BHMT

1. The faster evolutionary rate of BHMT2 overall suggests that selective constraints were reduced relative to BHMT.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-BHMT antibody

 Reference Product  PubMed Publications
 CBS antibody  >49 publications with BHMT and CBS
 MTHFR antibody  >48 publications with BHMT and MTHFR
 MAT1A antibody  >8 publications with BHMT and MAT1A
 AHCY antibody  >6 publications with BHMT and AHCY
 MAT2B antibody  >5 publications with BHMT and MAT2B
 MAT2A antibody  >5 publications with BHMT and MAT2A
 DMGDH antibody  >3 publications with BHMT and DMGDH
 CTH antibody  >2 publications with BHMT and CTH
 AHCYL2 antibody  >1 publications with BHMT and AHCYL2
 AHCYL1 antibody  >1 publications with BHMT and AHCYL1

Pathways associated with anti-BHMT antibody

 Products by Pathway  Pathway Diagram
 Choline Catabolism Pathway antibodies  Choline Catabolism Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Glycerophospholipid Biosynthesis Pathway antibodies  Glycerophospholipid Biosynthesis Pathway Diagram
 Glycine, Serine And Threonine Metabolism Pathway antibodies  Glycine, Serine And Threonine Metabolism Pathway Diagram
 Glycine, Serine And Threonine Metabolism Pathway antibodies  Glycine, Serine And Threonine Metabolism Pathway Diagram
 L-methionine Salvage From L-homocysteine Pathway antibodies  L-methionine Salvage From L-homocysteine Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram

Diseases associated with anti-BHMT antibody

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >37 publications with BHMT and Liver Diseases
 Cardiovascular Diseases Antibodies  >26 publications with BHMT and Cardiovascular Diseases
 Fatty Liver Antibodies  >16 publications with BHMT and Fatty Liver
 Heart Diseases Antibodies  >13 publications with BHMT and Heart Diseases
 Disease Models, Animal Antibodies  >13 publications with BHMT and Disease Models, Animal
 Liver Neoplasms Antibodies  >12 publications with BHMT and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >12 publications with BHMT and Carcinoma, Hepatocellular
 Drug-Induced Liver Injury Antibodies  >11 publications with BHMT and Drug-Induced Liver Injury
 Weight Gain Antibodies  >10 publications with BHMT and Weight Gain
 Kidney Diseases Antibodies  >8 publications with BHMT and Kidney Diseases

Organs/Tissues associated with anti-BHMT antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >138 publications with BHMT and Liver
 Kidney Antibodies  >31 publications with BHMT and Kidney
 Brain Antibodies  >13 publications with BHMT and Brain
 Intestine Antibodies  >4 publications with BHMT and Intestine
 Eye Antibodies  >3 publications with BHMT and Eye
 Embryonic Tissue Antibodies  >2 publications with BHMT and Embryonic Tissue
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