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BPGM Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS767166

MBS767166 is an antibody targeting BPGM. Also known as BPGM Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
BPGM, Polyclonal Antibody
Full Product Name
BPGM Rabbit Polyclonal
Product Gene Name
anti-BPGM antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
29,978 Da
Immunogen
2, 3-bisphosphoglycerate mutase
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-BPGM antibody
ELISA (EIA), Western Blot (WB)

Immunohistochemistry (IHC) of anti-BPGM antibody

Immunohistochemistry of paraffin-embedded human stomach using MBS767166 (BPGM Antibody) at dilution of 1:100
Rabbit Anti-BPGM Polyclonal Antibody – Cat# MBS767166

Western Blot (WB) of anti-BPGM antibody

HeLa cells were subjected to SDS PAGE followed by western blot with MBS767166 (BPGM antibody) at dilution of 1:1000
Rabbit Anti-BPGM Polyclonal Antibody, Western Blot (WB) – Cat# MBS767166

Other Notes

Small volumes of anti-BPGM antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BPGM. It may not necessarily be applicable to this product.

NCBI GI #
6680806
NCBI GeneID
12183
NCBI Accession #
NP_031589.1
UniProt Secondary Accession #
Q543Z6
UniProt Related Accession #
P15327
GenBank Nucleotide #
NM_007563.4
NCBI Official Full Name
bisphosphoglycerate mutase
NCBI Official Synonym Full Names
2,3-bisphosphoglycerate mutase
NCBI Official Symbol
Bpgm
NCBI Official Synonym Symbols
C86192; AI323730; AL022789
UniProt Protein Name
Bisphosphoglycerate mutase
UniProt Synonym Protein Names
2,3-bisphosphoglycerate mutase, erythrocyte; 2,3-bisphosphoglycerate synthase (EC:3.1.3.13, EC:5.4.2.11); BPG-dependent PGAM
Protein Family
Bisphosphoglycerate mutase
UniProt Gene Name
Bpgm
UniProt Synonym Gene Names
BPGM
UniProt Entry Name
PMGE_MOUSE
NCBI Protein Information
bisphosphoglycerate mutase

UniProt Comments for BPGM

BPGM: Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.1) and phosphatase (EC 3.1.3.13) activities. Defects in BPGM are the cause of bisphosphoglycerate mutase deficiency (BPGMD). A disease characterized by hemolytic anemia, splenomegaly, cholelithiasis and cholecystitis. Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.

Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; Phosphatase (non-protein); Isomerase; EC 5.4.2.11; EC 5.4.2.4; EC 3.1.3.13

Cellular Component: cytosol

Molecular Function: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity; bisphosphoglycerate mutase activity; bisphosphoglycerate phosphatase activity; catalytic activity; hydrolase activity; intramolecular transferase activity, phosphotransferases; isomerase activity; phosphoglycerate mutase activity

Biological Process: erythrocyte development; gluconeogenesis; glycolysis; metabolic process; regulation of pentose-phosphate shunt
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Research Articles on BPGM

1. Placental expression of BPGM can influence maternal 2,3-bisphosphoglycerate (BPG) blood levels and supports a hypothesis under which BPG synthesized in the placenta may act on maternal haemoglobin to enhance delivery of oxygen to the developing fetus.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-BPGM antibody

 Products by Pathway  Pathway Diagram
 Glucose Metabolism Pathway antibodies  Glucose Metabolism Pathway Diagram
 Glycine, Serine And Threonine Metabolism Pathway antibodies  Glycine, Serine And Threonine Metabolism Pathway Diagram
 Glycine, Serine And Threonine Metabolism Pathway antibodies  Glycine, Serine And Threonine Metabolism Pathway Diagram
 Glycolysis / Gluconeogenesis Pathway antibodies  Glycolysis / Gluconeogenesis Pathway Diagram
 Glycolysis / Gluconeogenesis Pathway antibodies  Glycolysis / Gluconeogenesis Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram
 Rapoport-Luebering Glycolytic Shunt Pathway antibodies  Rapoport-Luebering Glycolytic Shunt Pathway Diagram

Diseases associated with anti-BPGM antibody

 Disease Name  Pubmed Publications
 BISPHOSPHOGLYCERATE MUTASE DEFICIENCY Antibodies  >5 publications with BPGM and BISPHOSPHOGLYCERATE MUTASE DEFICIENCY
 Cardiovascular Diseases Antibodies  >2 publications with BPGM and Cardiovascular Diseases
 Lung Diseases Antibodies  >2 publications with BPGM and Lung Diseases
 Carcinoma, Squamous Cell Antibodies  >1 publications with BPGM and Carcinoma, Squamous Cell
 Lung Neoplasms Antibodies  >1 publications with BPGM and Lung Neoplasms
 Heart Diseases Antibodies  >1 publications with BPGM and Heart Diseases
 Kidney Diseases Antibodies  >1 publications with BPGM and Kidney Diseases

Organs/Tissues associated with anti-BPGM antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >2 publications with BPGM and Lung
 Embryonic Tissue Antibodies  >2 publications with BPGM and Embryonic Tissue
 Kidney Antibodies  >1 publications with BPGM and Kidney
 Heart Antibodies  >1 publications with BPGM and Heart
 Liver Antibodies  >1 publications with BPGM and Liver
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