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CADM3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS767423

MBS767423 is an antibody targeting CADM3. Also known as CADM3 Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CADM3, Polyclonal Antibody
Full Product Name
CADM3 Rabbit Polyclonal
Product Gene Name
anti-CADM3 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
38,326 Da
OMIM
609743
Immunogen
Cell adhesion molecule 3
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-CADM3 antibody
ELISA (EIA), Western Blot (WB)

Western Blot (WB) of anti-CADM3 antibody

Jurkat cells were subjected to SDS PAGE followed by western blot with MBS767423 (CADM3 antibody) at dilution of 1:800
Rabbit Anti-CADM3 Polyclonal Antibody – Cat# MBS767423

Other Notes

Small volumes of anti-CADM3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CADM3. It may not necessarily be applicable to this product.

NCBI GI #
11056046
NCBI GeneID
57863
NCBI Accession #
NP_067012.1
UniProt Secondary Accession #
Q8IZQ9; Q9NVJ5; Q9UJP1
UniProt Related Accession #
Q8N126
GenBank Nucleotide #
NM_021189.3
NCBI Official Full Name
cell adhesion molecule 3 isoform 1
NCBI Official Synonym Full Names
cell adhesion molecule 3
NCBI Official Symbol
CADM3
NCBI Official Synonym Symbols
BIgR; NECL1; TSLL1; IGSF4B; Necl-1; synCAM3
UniProt Protein Name
Cell adhesion molecule 3
UniProt Synonym Protein Names
Brain immunoglobulin receptor; Immunoglobulin superfamily member 4B; IgSF4B; Nectin-like protein 1; NECL-1; Synaptic cell adhesion molecule 3; SynCAM3; TSLC1-like protein 1; TSLL1
Protein Family
Cell adhesion molecule
UniProt Gene Name
CADM3
UniProt Synonym Gene Names
IGSF4B; NECL1; SYNCAM3; TSLL1; IgSF4B; NECL-1; SynCAM3; TSLL1
UniProt Entry Name
CADM3_HUMAN
NCBI Protein Information
cell adhesion molecule 3

NCBI Summary for CADM3

IGSF4B is a brain-specific protein related to the calcium-independent cell-cell adhesion molecules known as nectins (see PVRL3; MIM 607147) (Kakunaga et al., 2005 [PubMed 15741237]).[supplied by OMIM, Mar 2008]

UniProt Comments for CADM3

CADM3: Involved in the cell-cell adhesion. Has both calcium- independent homophilic cell-cell adhesion activity and calcium- independent heterophilic cell-cell adhesion activity with IGSF4, PVRL1 and PVRL3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions. Belongs to the nectin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 1q21.2-q22

Cellular Component: cell-cell adherens junction; integral to plasma membrane; intercellular junction; plasma membrane

Molecular Function: cell adhesion molecule binding; protein homodimerization activity; receptor activity; receptor binding

Biological Process: cell recognition; heterophilic cell adhesion; homophilic cell adhesion; protein localization
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Research Articles on CADM3

1. Nectin-based cell-cell adhesion was formed at the apical side of the junctional adhesion molecule (JAM)-based cell-cell adhesion; cadherin and claudin were recruited to the nectin-3 and JAM-based cell-cell adhesion sites to form AJ- and TJ-like domains.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CADM3 antibody

 Products by Pathway  Pathway Diagram
 Adherens Junctions Interactions Pathway antibodies  Adherens Junctions Interactions Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 Cell-cell Junction Organization Pathway antibodies  Cell-cell Junction Organization Pathway Diagram
 Nectin/Necl Trans Heterodimerization Pathway antibodies  Nectin/Necl Trans Heterodimerization Pathway Diagram

Diseases associated with anti-CADM3 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >2 publications with CADM3 and Inflammation
 Abnormalities, Multiple Antibodies  >1 publications with CADM3 and Abnormalities, Multiple
 Respiratory Tract Diseases Antibodies  >1 publications with CADM3 and Respiratory Tract Diseases
 Lung Neoplasms Antibodies  >1 publications with CADM3 and Lung Neoplasms

Organs/Tissues associated with anti-CADM3 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >3 publications with CADM3 and Nerve
 Brain Antibodies  >3 publications with CADM3 and Brain
 Eye Antibodies  >2 publications with CADM3 and Eye
 Kidney Antibodies  >1 publications with CADM3 and Kidney
 Embryonic Tissue Antibodies  >1 publications with CADM3 and Embryonic Tissue
 Muscle Antibodies  >1 publications with CADM3 and Muscle
 Prostate Antibodies  >1 publications with CADM3 and Prostate
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