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CD164 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS767665

MBS767665 is an antibody targeting CD164. Also known as CD164 Rabbit Polyclonal. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CD164, Polyclonal Antibody
Full Product Name
CD164 Rabbit Polyclonal
Product Gene Name
anti-CD164 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
16,736 Da
OMIM
603356
Immunogen
CD164 molecule, sialomucin
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-CD164 antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB), Flow Cytometry (FC/FACS)

Immunohistochemistry (IHC) of anti-CD164 antibody

Immunohistochemistry of paraffin-embedded human pancreas cancer using MBS767665 (CD164 antibody) at dilution of 1:50
Rabbit Anti-CD164 Polyclonal Antibody – Cat# MBS767665

Western Blot (WB) of anti-CD164 antibody

K-562 cells were subjected to SDS PAGE followed by western blot with MBS767665 (CD164 antibody) at dilution of 1:300
Rabbit Anti-CD164 Polyclonal Antibody, Western Blot (WB) – Cat# MBS767665

Other Notes

Small volumes of anti-CD164 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD164. It may not necessarily be applicable to this product.

NCBI GI #
9230741
NCBI GeneID
8763
NCBI Accession #
AAF85965.1
UniProt Secondary Accession #
O95413; Q5JSU6; Q9BPV0; Q9NR26; B4DQ85; E1P5E7; E1P5E8; E1P5E9
UniProt Related Accession #
Q04900
NCBI Official Full Name
CD164
NCBI Official Synonym Full Names
CD164 molecule
NCBI Official Symbol
CD164
NCBI Official Synonym Symbols
DFNA66; MGC-24; MUC-24; endolyn
UniProt Protein Name
Sialomucin core protein 24
UniProt Synonym Protein Names
Endolyn; Multi-glycosylated core protein 24; MGC-24; MGC-24v; CD_antigen: CD164
Protein Family
Sialomucin core protein
UniProt Gene Name
CD164
UniProt Synonym Gene Names
MUC-24; MGC-24; MGC-24v
UniProt Entry Name
MUC24_HUMAN
NCBI Protein Information
sialomucin core protein 24

NCBI Summary for CD164

Sialomucins are a heterogeneous group of secreted or membrane-associated mucins that appear to play 2 key but opposing roles in vivo: first as cytoprotective or antiadhesive agents, and second as adhesion receptors. CD164 is a type I integral transmembrane sialomucin that functions as an adhesion receptor (Watt et al., 1998 [PubMed 9680353]; Forde et al., 2007 [PubMed 17077324]).[supplied by OMIM, Aug 2008]
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UniProt Comments for CD164

CD164: Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34(+) cells to the stroma and by negatively regulating CD34(+)CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes. Belongs to the CD164 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 6q21

Cellular Component: endosome; endosome membrane; extracellular region; integral to plasma membrane; lysosomal membrane; lysosome; plasma membrane

Molecular Function: protein binding

Biological Process: cell adhesion; hemopoiesis; heterophilic cell adhesion; immune response; multicellular organismal development; muscle development; negative regulation of cell adhesion; negative regulation of cell proliferation; signal transduction
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Research Articles on CD164

1. This paper identified a new Deafness, Autosomal Dominant locus located on chromosome 6q15-21 and implicated CD164 as a novel gene for hearing impairment.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CD164 antibody

 Products by Pathway  Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram

Diseases associated with anti-CD164 antibody

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >5 publications with CD164 and Breast Neoplasms
 Prostatic Diseases Antibodies  >3 publications with CD164 and Prostatic Diseases
 Heart Diseases Antibodies  >3 publications with CD164 and Heart Diseases
 Cardiovascular Diseases Antibodies  >3 publications with CD164 and Cardiovascular Diseases
 Embryo Loss Antibodies  >2 publications with CD164 and Embryo Loss
 Necrosis Antibodies  >2 publications with CD164 and Necrosis
 Heart Defects, Congenital Antibodies  >1 publications with CD164 and Heart Defects, Congenital
 Edema Antibodies  >1 publications with CD164 and Edema
 Disease Models, Animal Antibodies  >1 publications with CD164 and Disease Models, Animal
 Inflammation Antibodies  >1 publications with CD164 and Inflammation

Organs/Tissues associated with anti-CD164 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >37 publications with CD164 and Blood
 Bone Antibodies  >22 publications with CD164 and Bone
 Bone Marrow Antibodies  >21 publications with CD164 and Bone Marrow
 Kidney Antibodies  >7 publications with CD164 and Kidney
 Embryonic Tissue Antibodies  >7 publications with CD164 and Embryonic Tissue
 Umbilical Cord Antibodies  >4 publications with CD164 and Umbilical Cord
 Muscle Antibodies  >4 publications with CD164 and Muscle
 Intestine Antibodies  >3 publications with CD164 and Intestine
 Uterus Antibodies  >3 publications with CD164 and Uterus
 Prostate Antibodies  >3 publications with CD164 and Prostate
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