CHRNB4 Antibody – Rabbit Polyclonal

nAChRB4: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Beta- 4/CHRNB4 sub-subfamily.

Protein type: Membrane protein, integral; Channel, ligand-gated; Channel, cation; Membrane protein, multi-pass; Receptor, misc.

Chromosomal Location of Human Ortholog: 15q24

Cellular Component: cell junction; integral to membrane; integral to plasma membrane; neuron projection; nicotinic acetylcholine-gated receptor-channel complex; plasma membrane; postsynaptic membrane

Molecular Function: acetylcholine binding; acetylcholine receptor activity; drug binding; ligand-gated ion channel activity; nicotinic acetylcholine-activated cation-selective channel activity; protein heterodimerization activity

Biological Process: behavioral response to nicotine; ion transport; locomotory behavior; positive regulation of transmission of nerve impulse; protein heterooligomerization; regulation of action potential; regulation of neurotransmitter secretion; regulation of smooth muscle contraction; response to nicotine; signal transduction; smooth muscle contraction; synaptic transmission involved in micturition; synaptic transmission, cholinergic