Rabbit Anti-CLASP2 Polyclonal Antibody – Cat# MBS767963

Human brain tissue were subjected to SDS PAGE followed by western blot with MBS767963 (CLASP2 antibody) at dilution of 1:1000

CLASP2 Antibody – Rabbit Polyclonal

Name: CLASP2 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS767963
Price: 330 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS767963

MBS767963 is an antibody targeting CLASP2. Also known as CLASP2 Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

CLASP2, Polyclonal Antibody

Full Product Name

CLASP2 Rabbit Polyclonal

Product Gene Name

anti-CLASP2 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

Liquid

Purity/Purification

>=95% as determined by SDS-PAGE
Immunogen Affinity Purified

Preparation and Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Molecular Weight

165,924 Da

OMIM

605853

Immunogen

Cytoplasmic linker associated protein 2

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-CLASP2 antibody

ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-CLASP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CLASP2. It may not necessarily be applicable to this product.

NCBI GI #

333440449

NCBI GeneID

23122

NCBI Accession #

NP_055912.2

UniProt Secondary Accession #

Q7L8F6; Q8N6R6; Q9BQT3; Q9BQT4; Q9H7A3; Q9NSZ2; B2RTR1; F5H604

UniProt Related Accession #

O75122

GenBank Nucleotide #

NM_015097.2

NCBI Official Full Name

CLIP-associating protein 2 isoform 1

NCBI Official Synonym Full Names

cytoplasmic linker associated protein 2

NCBI Official Symbol

CLASP2

UniProt Protein Name

CLIP-associating protein 2

UniProt Synonym Protein Names

Cytoplasmic linker-associated protein 2; Protein Orbit homolog 2; hOrbit2

Protein Family

CLIP-associating protein

UniProt Gene Name

CLASP2

UniProt Synonym Gene Names

KIAA0627; hOrbit2

UniProt Entry Name

CLAP2_HUMAN

NCBI Protein Information

CLIP-associating protein 2

UniProt Comments for CLASP2

CLASP2: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. Belongs to the CLASP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 3p22.3

Cellular Component: basal cortex; cell cortex; cytoplasm; cytoplasmic microtubule; cytosol; focal adhesion; Golgi apparatus; kinetochore; kinetochore microtubule; leading edge; membrane; microtubule; microtubule organizing center; plasma membrane; trans-Golgi network

Molecular Function: actin filament binding; microtubule binding; microtubule plus-end binding; protein binding

Biological Process: cell division; establishment and/or maintenance of cell polarity; exit from mitosis; Golgi organization and biogenesis; microtubule cytoskeleton organization and biogenesis; microtubule nucleation; microtubule organizing center organization and biogenesis; mitotic spindle organization and biogenesis; negative regulation of focal adhesion formation; negative regulation of microtubule depolymerization; negative regulation of stress fiber formation; positive regulation of exocytosis; regulation of actin cytoskeleton organization and biogenesis; regulation of axon extension; regulation of gastrulation; regulation of microtubule polymerization; regulation of microtubule polymerization or depolymerization; regulation of microtubule-based process; sister chromatid cohesion; vesicle targeting

Research Articles on CLASP2

1. PAR3 and aPKC control the organization of the Golgi through CLASP2 phosphorylation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CLASP2 antibody

Reference Product	PubMed Publications
GSK3B antibody	>9 publications with CLASP2 and GSK3B
MAPRE1 antibody	>1 publications with CLASP2 and MAPRE1

Pathways associated with anti-CLASP2 antibody

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle, Mitotic Pathway antibodies	Cell Cycle, Mitotic Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
M Phase Pathway antibodies	M Phase Pathway Diagram
Mitotic Anaphase Pathway antibodies	Mitotic Anaphase Pathway Diagram
Mitotic Metaphase And Anaphase Pathway antibodies	Mitotic Metaphase And Anaphase Pathway Diagram
Mitotic Prometaphase Pathway antibodies	Mitotic Prometaphase Pathway Diagram
RHO GTPase Effectors Pathway antibodies	RHO GTPase Effectors Pathway Diagram
RHO GTPases Activate Formins Pathway antibodies	RHO GTPases Activate Formins Pathway Diagram

Diseases associated with anti-CLASP2 antibody

Disease Name	Pubmed Publications
Congenital Abnormalities Antibodies	>2 publications with CLASP2 and Congenital Abnormalities
Chromosome Aberrations Antibodies	>2 publications with CLASP2 and Chromosome Aberrations
Urogenital Abnormalities Antibodies	>1 publications with CLASP2 and Urogenital Abnormalities
Anemia Antibodies	>1 publications with CLASP2 and Anemia
Hyperplasia Antibodies	>1 publications with CLASP2 and Hyperplasia
Abnormalities, Multiple Antibodies	>1 publications with CLASP2 and Abnormalities, Multiple
Neurobehavioral Manifestations Antibodies	>1 publications with CLASP2 and Neurobehavioral Manifestations
Breast Neoplasms Antibodies	>1 publications with CLASP2 and Breast Neoplasms

Organs/Tissues associated with anti-CLASP2 antibody

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>8 publications with CLASP2 and Nerve
Brain Antibodies	>6 publications with CLASP2 and Brain
Muscle Antibodies	>5 publications with CLASP2 and Muscle
Spinal Cord Antibodies	>3 publications with CLASP2 and Spinal Cord
Vascular Antibodies	>2 publications with CLASP2 and Vascular
Eye Antibodies	>2 publications with CLASP2 and Eye
Blood Antibodies	>2 publications with CLASP2 and Blood
Heart Antibodies	>1 publications with CLASP2 and Heart
Lung Antibodies	>1 publications with CLASP2 and Lung
Ear Antibodies	>1 publications with CLASP2 and Ear