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CLDN11 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS9132371
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This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular… More details

$225 / 0.02 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CLDN11, Polyclonal Antibody
Full Product Name
CLDN11 Polyclonal Antibody
Product Gene Name
anti-CLDN11 antibody
Product Synonym Names
OSP; OTM
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
22kDa
OMIM
AF068863 mRNA
3D Structure
ModBase 3D Structure for O75508
Immunogen
A synthetic peptide of human CLDN11
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Product Categories/Family for anti-CLDN11 antibody

Primary antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CLDN11 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CLDN11 antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Western Blot (WB) of anti-CLDN11 antibody

Western blot analysis of extracts of various cell lines, using CLDN11 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 90s.
Rabbit Anti-CLDN11 Polyclonal Antibody – Cat# MBS9132371

Other Notes

Small volumes of anti-CLDN11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CLDN11 purchase

MBS9132371 is an antibody targeting CLDN11. Also known as CLDN11 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CLDN11. It may not necessarily be applicable to this product.

NCBI GI #
6685300
NCBI GeneID
5010
NCBI Accession #
O75508.2
UniProt Primary Accession #
O75508
UniProt Secondary Accession #
Q5U0P3; B2R7C1; D3DNQ5
UniProt Related Accession #
O75508
NCBI Official Full Name
Claudin-11
NCBI Official Synonym Full Names
claudin 11
NCBI Official Symbol
CLDN11
NCBI Official Synonym Symbols
OSP; OTM
UniProt Protein Name
Claudin-11
UniProt Synonym Protein Names
Oligodendrocyte-specific protein
Protein Family
Claudin
UniProt Gene Name
CLDN11
UniProt Synonym Gene Names
OSP; OTM
NCBI Protein Information
claudin-11

UniProt Comments for CLDN11

Claudin-11: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Belongs to the claudin family.

Protein type: Cell adhesion; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 3q26.2

Cellular Component: plasma membrane; tight junction

Molecular Function: identical protein binding; protein binding

Biological Process: calcium-independent cell-cell adhesion
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Research Articles on CLDN11

1. the expression of miR-99b was inversely correlated with CLDN11 levels . These findings suggest that a high level of miR-99b expression is an independent prognostic factor and correlates with poor survival of patients with Hepatocellular carcinoma (HCC)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CLDN11 antibody

 Reference Product  PubMed Publications
 TJP1 antibody  >11 publications with CLDN11 and TJP1
 OCLN antibody  >11 publications with CLDN11 and OCLN
 CLDN3 antibody  >8 publications with CLDN11 and CLDN3
 CLDN4 antibody  >5 publications with CLDN11 and CLDN4
 CLDN10 antibody  >1 publications with CLDN11 and CLDN10
 TJP2 antibody  >1 publications with CLDN11 and TJP2

Pathways associated with anti-CLDN11 antibody

 Products by Pathway  Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 Cell-cell Junction Organization Pathway antibodies  Cell-cell Junction Organization Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram

Diseases associated with anti-CLDN11 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >24 publications with CLDN11 and Nervous System Diseases
 Immune System Diseases Antibodies  >13 publications with CLDN11 and Immune System Diseases
 Brain Diseases Antibodies  >11 publications with CLDN11 and Brain Diseases
 Infertility, Male Antibodies  >8 publications with CLDN11 and Infertility, Male
 Inflammation Antibodies  >5 publications with CLDN11 and Inflammation
 Necrosis Antibodies  >2 publications with CLDN11 and Necrosis
 Nervous System Malformations Antibodies  >1 publications with CLDN11 and Nervous System Malformations
 Ovarian Diseases Antibodies  >1 publications with CLDN11 and Ovarian Diseases
 Abnormalities, Multiple Antibodies  >1 publications with CLDN11 and Abnormalities, Multiple
 Abnormalities, Drug-Induced Antibodies  >1 publications with CLDN11 and Abnormalities, Drug-Induced

Organs/Tissues associated with anti-CLDN11 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >68 publications with CLDN11 and Nerve
 Testis Antibodies  >41 publications with CLDN11 and Testis
 Brain Antibodies  >17 publications with CLDN11 and Brain
 Skin Antibodies  >7 publications with CLDN11 and Skin
 Spinal Cord Antibodies  >6 publications with CLDN11 and Spinal Cord
 Ear Antibodies  >6 publications with CLDN11 and Ear
 Embryonic Tissue Antibodies  >5 publications with CLDN11 and Embryonic Tissue
 Kidney Antibodies  >5 publications with CLDN11 and Kidney
 Bone Antibodies  >3 publications with CLDN11 and Bone
 Vascular Antibodies  >2 publications with CLDN11 and Vascular
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