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CNN2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS768033

MBS768033 is an antibody targeting CNN2. Also known as CNN2 Mouse Monoclonal. Reactive in Human, Pig. Host: Mouse. More details

$345 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CNN2, Monoclonal Antibody
Full Product Name
CNN2 Mouse Monoclonal
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a
Host
Mouse
Species Reactivity
Human, Pig
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Protein A+G purification
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
29,500 Da
OMIM
602373
Immunogen
Calponin 2
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-CNN2 antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)

Immunohistochemistry (IHC) of anti-CNN2 antibody

Immunohistochemistry of paraffin-embedded human breast hyperplasia tissue slide using MBS768033 (CNN2 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer (pH9) .
Mouse Anti-CNN2 Monoclonal Antibody – Cat# MBS768033

Western Blot (WB) of anti-CNN2 antibody

pig stomach tissue were subjected to SDS PAGE followed by western blot with MBS768033 (CNN2 Antibody) at dilution of 1:2000
Mouse Anti-CNN2 Monoclonal Antibody, Western Blot (WB) – Cat# MBS768033

Other Notes

Small volumes of anti-CNN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CNN2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
calponin-2 isoform d
NCBI Official Synonym Full Names
calponin 2
NCBI Official Symbol
CNN2
UniProt Protein Name
Calponin-2
UniProt Synonym Protein Names
Calponin H2, smooth muscle; Neutral calponin
Protein Family
UniProt Gene Name
CNN2
UniProt Entry Name
CNN2_HUMAN
NCBI Protein Information
calponin-2

NCBI Summary for CNN2

The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Several pseudogenes of this gene have been identified, and are present on chromosomes 1, 2, 3, 6, 9, 11, 13, 15, 16, 21 and 22. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
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UniProt Comments for CNN2

calponin 2: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. Belongs to the calponin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Actin-binding

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: cytoskeleton; focal adhesion; intercellular junction; membrane; stress fiber

Molecular Function: actin binding; calmodulin binding

Biological Process: actomyosin structure organization and biogenesis; cytoskeleton organization and biogenesis; regulation of actin filament-based process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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