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CNOT4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9506166

MBS9506166 is an antibody targeting CNOT4. Also known as CNOT4 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$300 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CNOT4, Polyclonal Antibody
Full Product Name
CNOT4 Antibody
Product Gene Name
Product Synonym Names
CCR4-associated factor 4; CCR4-NOT transcription 4; CNO4; CNOT4; E3 ubiquitin protein ligase CNOT4; negative regulator of transcription 4; NOT4; NOT4H; transcriptional repressor NOT4Hp
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration
1 mg/ml (lot specific)
Specificity
CNOT4 Antibody detects endogenous levels of total CNOT4 protein.
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Molecular Weight
63 kDa
OMIM
U71267 mRNA
3D Structure
ModBase 3D Structure for O95628
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human CNOT4.
Immunogen Range
61-110
Applications Tested/Suitable for anti-CNOT4 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-CNOT4 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:20000

Immunohistochemistry (IHC) of anti-CNOT4 antibody

Immunohistochemistry analysis of paraffin-embedded human testis tissue, using CNOT4 Antibody. The picture on the right is blocked with the synthesized peptide.
Rabbit Anti-CNOT4 Polyclonal Antibody – Cat# MBS9506166

Western Blot (WB) of anti-CNOT4 antibody

Western blot analysis of lysates from Jurkat and K562 cells, using CNOT4 Antibody. The lane on the right is blocked with the synthesized peptide.
Rabbit Anti-CNOT4 Polyclonal Antibody, Western Blot (WB) – Cat# MBS9506166

Other Notes

Small volumes of anti-CNOT4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CNOT4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
CCR4-NOT transcription complex subunit 4 isoform b
NCBI Official Synonym Full Names
CCR4-NOT transcription complex subunit 4
NCBI Official Symbol
CNOT4
NCBI Official Synonym Symbols
NOT4; NOT4H; CLONE243
UniProt Protein Name
CCR4-NOT transcription complex subunit 4
UniProt Synonym Protein Names
CCR4-associated factor 4; E3 ubiquitin-protein ligase CNOT4; Potential transcriptional repressor NOT4Hp; RING-type E3 ubiquitin transferase CNOT4Curated
UniProt Gene Name
CNOT4
UniProt Synonym Gene Names
NOT4
NCBI Protein Information
CCR4-NOT transcription complex subunit 4

NCBI Summary for CNOT4

The protein encoded by this gene is a subunit of the CCR4-NOT complex, a global transcriptional regulator. The encoded protein interacts with CNOT1 and has E3 ubiquitin ligase activity. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]
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UniProt Comments for CNOT4

Has E3 ubiquitin ligase activity. Involved in activation of the JAK/STAT pathway.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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