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CPSF6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS768172

MBS768172 is an antibody targeting CPSF6. Also known as CPSF6 Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CPSF6, Polyclonal Antibody
Full Product Name
CPSF6 Rabbit Polyclonal
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
52,326 Da
OMIM
604979
Immunogen
Cleavage and polyadenylation specific factor 6, 68kDa
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-CPSF6 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Immunohistochemistry (IHC) of anti-CPSF6 antibody

Immunohistochemistry of paraffin-embedded human kidney using MBS768172 (CPSF6 antibody) at dilution of 1:50
Rabbit Anti-CPSF6 Polyclonal Antibody – Cat# MBS768172

Testing Data of anti-CPSF6 antibody

Rabbit Anti-CPSF6 Polyclonal Antibody, Testing Data – Cat# MBS768172

Western Blot (WB) of anti-CPSF6 antibody

HeLa cells were subjected to SDS PAGE followed by western blot with MBS768172 (CPSF6 antibody) at dilution of 1:100
Rabbit Anti-CPSF6 Polyclonal Antibody, Western Blot (WB) – Cat# MBS768172

Other Notes

Small volumes of anti-CPSF6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CPSF6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cleavage and polyadenylation specificity factor subunit 6 isoform 2
NCBI Official Synonym Full Names
cleavage and polyadenylation specific factor 6
NCBI Official Symbol
CPSF6
NCBI Official Synonym Symbols
CFIM; CFIM68; HPBRII-4; HPBRII-7
UniProt Protein Name
Cleavage and polyadenylation specificity factor subunit 6
UniProt Synonym Protein Names
Cleavage and polyadenylation specificity factor 68 kDa subunit; CFIm68; CPSF 68 kDa subunit; Pre-mRNA cleavage factor Im 68 kDa subunit; Protein HPBRII-4/7
UniProt Gene Name
CPSF6
UniProt Synonym Gene Names
CFIM68; CFIm68; CPSF 68 kDa subunit
UniProt Entry Name
CPSF6_HUMAN
NCBI Protein Information
cleavage and polyadenylation specificity factor subunit 6

NCBI Summary for CPSF6

The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. [provided by RefSeq, Jul 2008]
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UniProt Comments for CPSF6

CPSF6: Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping. Belongs to the RRM CPSF6/7 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Spliceosome; RNA-binding; RNA processing

Chromosomal Location of Human Ortholog: 12q15

Cellular Component: membrane; mRNA cleavage factor complex; nucleoplasm; nucleus; paraspeckles; ribonucleoprotein complex

Molecular Function: mRNA binding; nucleotide binding; protein binding; RNA binding

Biological Process: mRNA polyadenylation; mRNA processing; protein tetramerization
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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